毒性弥漫性甲状腺肿(Graves'disease,GD)是自身免疫性甲状腺疾病[1],是由体内的抗促甲状腺激素受体抗体(Thyrotropin receptor antibody,TRAb)刺激甲状腺细胞上的TSH(Thyroid stimulating hormone)受体,引起甲状腺激素生成和释放增多所致,也是引起甲亢最常见的原因.瑞典一项流行病学调查研究显示,在碘充足地区,平均每年10万人中约有21.4人发病[2].美国流行病学研究报告在1935年至1967年期间GD每年每10万人中发病30例[3].在中国强制性引入通用碘化盐16年后,一项中国10城市的横断面研究显示,在碘摄入过量地区GD的患病率是0.8%,在碘摄入量充足的地区GD的患病率是0.5%[4].大约有3%的女性和0.5%的男性罹患GD[1].30-60岁为发病的高峰年龄,其中女性多发.近年来,GD发病率逐渐上升.若病情控制不佳,容易造成神经系统、循环系统、眼部病变、血液系统、消化系统等损害[5].
Objective To observe TCM syndrome types in patients(pts) with primary liver cancer(PLC) before and after high intensity focus ultrasound(HIFU) treatment,and to explore the influence of HIFU treatment on TCM syndrome types.Methods Based on the data of 64 PLC pts with HIFU treatment,TCM Syndrome types were analyzed before and after HIFU treatment.Principal TCM Syndrome was qi-deficiency syndrome,blood-deficiency syndrome,yin-deficiency syndrome,qi-stagnation syndrome,blood stasis syndrome,damp-blocking syndrome,etc.Results There were significantly differences in qi-stagnation syndrome,blood stasis syndrome and qi-deficiency syndrome in pts who received HIFU treatment 3 days and one week later compared to themselves when had not had before(P0.01 or P0.05).There were significantly differences in yin-deficiency syndrome in pts who received HIFU treatment one week later compared to themselves when received HIFU treatment 3 days later or had not had before(P0.05).Conclusion HIFU treatment could significantly relieve symptoms of qi-stagnation syndrome and blood stasis syndrome.But it could also aggravate symptoms of qi-deficiency syndrome and yin-deficiency syndrome.The result suggested that HIFU treatment could not radically change the pathogenesis of PLC.
In TCM,the theory of Wu-Xing is wildly used to explain those macroscopic phenomena,but it's also can be used to explain the development of a specific disease.The feasibility of the prevention and treatments to tumors by the theory of Wu-Xing is explored in the article.By analyzing the misbalance of Wu-Xing during the initiating,the developing,and the necrosis of tumors,the theory of Wu-Xing is considered to be useful for the explanations from TCM theory to those newly studies on tumors,and to be helpful for the development of TCM.
大师,指有巨大成就,而为人所宗仰的学者,学科的发展大师级人物的出现常具有里程碑的作用.然而大师又不能自封,不可吹捧,更不能"海选",往往要经过数十年,乃至数百年的实践检验,以及同行的广泛认可才能确立,故历代学界又慎言大师.
目的探索肺癌转移发生与中医脏象理论的相关性。方法以既往临床肺癌病例为对象,根据中医脏象理论,对患者转移灶所属部位及临床证候学表现进行收集,并按照脾虚痰湿、阴虚热毒、气阴两虚、气血瘀滞4个证型对各种不同器官的转移进行证候学评分。归纳、总结转移及证候学评分情况并将该证候与所发生之转移部位的关系进行分析,提出肺癌转移与中医脏象理论的相关性规律。结果①气阴两虚证是最常见的证型,占单器官及首发转移器官证型分布例次的40.34%;②在每种证型中,各不同转移器官的分布均有显著性差异(P<0.01)。③肝转移中各证型的分布有显著性差异(P<0.01)。结论肺癌出现不同中医证候可以提示其转移方向。
一、症状明显时,辨证用中药 肝区不适,气郁不舒.表现为肝区或两胁下不舒服,或胀满,或隐隐作痛,并伴有心情不愉快、容易发怒、心烦、急躁等.可以用柴胡、香附、佛手、白芍、当归、郁金、谷芽、麦芽等.