In healthy dogs and in dogs with experimental myocardial infarct, the smallest current applied through a pacing wire which would produce a disturbance in rhythm was 60 μA. This figure is higher than most recommended standards for earth-free monitoring equipment. Much bigger currents were required to produce a disturbance from a wire in the right atrium, which appears to be a safe location for catheters and pacing wires.

1. The oxygen capacities of foetal and adult blood have been compared by direct measurement of their oxygen and carbon monoxide combining power. Corrections have been applied to the capacities obtained from oxygen content determinations for the presence of carboxyhaemoglobin and methaemoglobin. 2. Mean values for the capacities of foetal blood derived from oxygen and carbon monoxide content were 1·312 ml./g ( S.E. ± 0·007) and 1·331 ( S.E. ± 0·002) respectively, while those for adult blood were 1·306 ml./g ( S.E. ± 0·006) and 1·331 ( S.E. ± 0·0005) respectively. 3. For neither carbon monoxide nor oxygen was there a significant difference ( P > 0·05) of capacity between adult and foetal blood. There was, however, a significant difference ( P < 0·05) on comparing the two methods of measurement on each form of blood and values from both methods were significantly different ( P < 0·001) from the theoretical value of 1·39 ml. oxygen/g haemoglobin derived from the molecular weight of haemoglobin. 4. These results suggest that the International Cyanmethaemoglobin Standard gives values of haemoglobin concentration which are approximately 6% higher than levels indicated by oxygen combining power.

SUMMARY Fresh heparinized and ACD stored blood from smokers showed a reduced oxygen content when equilibrated with 95 per cent oxygen in vitro for 30–45 min This was associated with a raised carboxyhaemoglobin level, which persisted beyond the normal 21-day period of storage of donor blood.

Conference Abstract| August 01 1971 Oxygen Combining Power of Haemoglobin I. C. Gregory; I. C. Gregory 1Department of Anaesthetics, M.R.C. Clinical Research Centre, Northwick Park, Harrow, Middlesex HA1 3UJ Search for other works by this author on: This Site PubMed Google Scholar G. H. Hulands; G. H. Hulands 1Department of Anaesthetics, M.R.C. Clinical Research Centre, Northwick Park, Harrow, Middlesex HA1 3UJ Search for other works by this author on: This Site PubMed Google Scholar R. A. Millar R. A. Millar 1Department of Anaesthetics, M.R.C. Clinical Research Centre, Northwick Park, Harrow, Middlesex HA1 3UJ Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd © 1971 The Biochemical Society and the Medical Research Society1971 Clin Sci (1971) 41 (2): 7P. https://doi.org/10.1042/cs041007Pa Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation I. C. Gregory, G. H. Hulands, R. A. Millar; Oxygen Combining Power of Haemoglobin. Clin Sci 1 August 1971; 41 (2): 7P. doi: https://doi.org/10.1042/cs041007Pa Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 1971 The Biochemical Society and the Medical Research Society1971 Article PDF first page preview Close Modal You do not currently have access to this content.