Chromatographic modifications have been made in the tetracycline fluorescence test for gastric cancer designed to improve its reliability. In limited studies using these modified procedures, tetracycline fluorescence was identified in the gastric sediments of 10 (91 %) of 11 patients with cancer of the stomach. By contrast, tetracycline fluorescence was not found on paper chromatography in the gastric sediments of 62 subjects with either normal stomachs or various benign lesions of the stomach. These promising but preliminary results are reported to encourage trial of these methods in areas where gastric cancer is prevalent.

SINCE ITS INTRODUCTION in 1933 (1) considerable attention has been given the product dihydrotachysterol or A.T.Io (antitetanisches Praparat Nr.Io). Holt (2, 3) found it would relieve the tetany in parathyroidectomized animals and keep the blood calcium apparently normal, and the literature contains a number of articles attesting to its effectiveness in the treatment of hypocalcemia of hypoparathyroidism (4–28). The reports in the American literature dealing with the clinical use of dihydrotachysterol are still few in number. Hence, it was felt desirable to report our clinical expert ence with the preparation in the management of a case of idiopathic hypecalcemia, probably of hypoparathyroid origin. History. A 54 year old Jewish housewife was admitted to the Jewish Hospital on November 28, 1938. Twelve years prior to admission she had experienced rather sudden spontaneous menopausal changes with which were associated few symptoms. However, complaints such as tiredness, weakness, ‘dragging down’ feeling and an inability to carry on as well as formerly dated from this time despite frequent medical attention.