Abstract Background Tooth loss is a common problem that affects many people worldwide. Exploring knowledge, attitude, and practice (KAP) among patients can identify barriers and challenges in following recommended practices, providing valuable insights for dental healthcare providers, policymakers, and researchers. This study aimed to explore the KAP of patients with dental arch deficiencies regarding tooth loss and dentures. Methods This web-based, cross-sectional study was conducted among patients with dental arch deficiencies using a self-designed questionnaire. Result 3166 valid questionnaires were included. Participants’ mean KAP scores were 6.84 ± 2.27 (possible range: 0 ~ 12), 39.4 ± 3.72 (possible range: 9 ~ 45), and 27.7 ± 4.36 (possible range: 8 ~ 40), respectively. Multivariable logistic regression analysis showed that knowledge (OR = 1.383), employed (OR = 1.805), family history (OR = 2.158), and treatment (OR = 1.683) were independently associated with attitude. Moreover, knowledge (OR = 1.239), attitude (OR = 1.250), female (OR = 0.619), age (OR = 0.967), college/bachelor (OR = 0.373), and master and above degree (OR = 0.418), employed (OR = 0.554) or student (OR = 0.434), with 10,001–20,000 Yuan household income per month (OR = 0.492), have been married (OR = 0.609), smoking (OR = 0.595), drinking (OR = 0.397), disease duration (OR = 0.972), with family history (OR = 1.676), and with treatment (OR = 3.492) were independently associated with practice (all P < 0.05). Conclusion Patients with dental arch deficiencies have insufficient knowledge, positive attitudes, and moderate practice toward tooth loss and dentures, which might be affected by multiple demographic factors.

Dental filling is a prevalent method for treating dental defects. This study aimed to investigate the knowledge, attitude, and practice (KAP) toward dental defects and dental fillings among dental patients in Jinan, Shandong Province, China. This cross-sectional study was conducted at the main campus and several branch campuses of Jinan Stomatological Hospital, and community locations within Jinan city between October 2023, and January 2024. Spearman correlation analysis and mediation analysis were used to assess the associations and interrelationships between KAP scores. In this study, 2529 dental patients participated, with 69.1

The development of periodontal disease is closely linked to individual oral healthcare behaviors. This study aimed to investigate the knowledge, attitude, and practice (KAP) toward the self-control of dental plaque among patients with periodontal diseases. This cross-sectional study was conducted at Jinan Stomatological Hospital between July 2022 and September 2022 through a self-administrated questionnaire for patients with periodontal diseases. A total of 563 participants were included. Among them, 147 (26.11

Objective. This study aimed to investigate and analyse the clinical efficacy and safety of periocline-assisted periodontal foundation in the therapy of chronic periodontitis. Methods. From May 2018 to January 2021, 108 patients with chronic periodontitis were treated at our institution and randomly assigned equally to either the control or the experimental group. The plaque index (PLI), sulcus bleeding index (SBI), probing depth (PD), and periodontal attachment level (AI) were evaluated before and after periodontal basic therapy in the control group and periocline as an adjunct in the experimental group. Lactobacillus (LB) and Porphyromonas gingivalis (PG) concentrations in saliva were measured before and after therapy, and adverse responses during treatment were noted. Results. The levels of PLI, SBI, PD, and AI in the two groups were significantly lower in both groups at 1 and 3 months posttreatment compared to baseline; the levels of PLI and SBI were higher, and the levels of PD and AI were lower at 3 months after treatment compared to 1 month after treatment; compared with the control group at 1 month and 3 months after treatment, the levels of PLI, SBI, PD, and AI in the experimental group were lower than those in the control group ( P < 0.05 ). The LB level was higher and the PG level was lower in both groups compared to baseline at 1 and 3 months posttreatment. The LB level was higher and the PG level was lower at 3 months posttreatment compared to 1 month after treatment. Compared with the control group at 1 month and 3 months after treatment, the LB level was higher, and the PG level was lower in the experimental group ( P < 0.05 ). No significant adverse effects were observed in either group during the treatment period. Only 1 patient in the experimental group had mild gastrointestinal reactions, mainly nausea, without obvious neurological symptoms or abnormal blood changes, which did not affect the treatment. Conclusion. Periodontal fundamental therapy with perioclines may be a potential treatment for persistent periodontitis. It improves the primary clinical indicators, increases dysbacteriosis control, and has a strong safety profile. It could effectively control the development of clinical symptoms of periodontitis and reduce tissue destruction, with obvious clinical treatment effects. It could be used as the first choice for topical treatment of chronic periodontitis. It is recommended for further study by a wide range of researchers.

Introduction:The oncogenic role of lncRNA LUADT1 has been investigated only in lung cancer.This study aimed to investigate the role of LUADT1 in oral squamous cell carcinoma (OSCC).Patients and Methods: The expression levels of LUADT1 in paired OSCC and non-tumor tissues from OSCC patients were determined by RT-qPCR.A 5-year follow-up study was performed to analyze the prognostic value of LUADT1 for OSCC.Dual-luciferase assay and overexpression experiments were performed to assess the interactions among LUADT1, miR-34a and GASL1.Cell proliferation was analyzed by cell proliferation assay.Results: In this study, we found that LUADT1 was upregulated in OSCC and predicted poor survival.LUADT1 was predicted to interact with miR-34a, which was confirmed by dualluciferase activity assay.However, overexpression experiments showed that they did not affect the expression of each other.Interestingly, overexpression of LUADT1 resulted in upregulation of GAS1, a target of miR-34a.Cell proliferation assay revealed that overexpression of LUADT1 and GAS1 resulted in promoted cell proliferation.MiR-34a played an opposite role and reversed the effects of LUADT1 overexpression.Conclusion: LUADT1 may promote OSCC proliferation by regulating miR-34a/GAS1 axis.

目的:了解下颌第三磨牙阻生牙患者的流行病学分布特征及其对干槽症发病的影响.方法:分析1 777例下颌第三磨牙阻生牙拔出患者的年龄、性别、拔牙月份、牙位、阻生类型等流行病学特征的分布情况,并采用多因素Logistic回归分析探讨其与干槽症发病的关系.结果:1 777例患者平均年龄(33.69±11.57)岁,女性患者(60.33％)多于男性(39.67％),垂直阻生和近中阻生患者最多(37.76％和31.40％),颊侧阻生患者最少(0.79％).共有15例患者发生干槽症,发病率0.84％.多因素Logistic回归分析结果显示,5～ 10月拔除下颌第三磨牙阻生牙(OR =4.07,95％CI:1.08～15.42)、远中阻生(OR=12.19,95％CI:1.19～125.01)、舌侧阻生(OR=15.30,95％CI:2.59 ～90.36)与干槽症发病均呈正相关(P＜0.05).结论:下颌第三磨牙阻生牙拔除患者中女性较多,阻生类型以垂直阻生和近中阻生为主,较炎热季节行拔牙术、阻生类型是干槽症发病的危险因素.