Pseudocarcinomatous hyperplasia of the fallopian tube is an entity rarely described in the literature. It is generally associated with endogenous or exogenous ovarian stimulation or secondary to underlying inflammation (pelvic inflammatory disease). It can cause a problem of differential diagnosis with adenocarcinoma. We report the case of a 34-year-old woman with secondary infertility who underwent surgery for bilateral hydrosalpinx and polymyomatous uterus. Anatomopathological study revealed granulomatous salpingitis without caseous necrosis, with bilateral tubal pseudocarcinomatous hyperplasia. In this case, we discuss the elements of the positive and differential diagnosis of this tubal lesion.

Background: Eye metastases are a rare event in cancer, patients with breast cancer being the most common primary site (28.5%–58.8%). Patients with ocular metastatic disease can present with a variable clinical picture. Most often presents as a cutaneous or subcutaneous nodule simulating a chalazion but with rapid growth and possible superficial ulceration. The definitive diagnosis is based on the anatomopathological analysis of the lesion. The treatment remains palliative and the prognosis remains poor. Objectives: To further define the histopathologic features of breast carcinoma conducive to orbital metastasis. Methods: We report a case of ocular metastasis in a 46-year-old woman presenting with right eye pain. She had been treated for ductal carcinoma breast cancer with lymph node and bone metastases 5 years ago; a mastectomy with lymph node dissection was performed. The patient consults us for unilateral eyelid swellings evolving for 4 months. On examination, we find well-limited rounded tissue formation in the right upper eyelid ulcerated in places. Oculomotricity was preserved and the rest of the examination was unremarkable. A biopsy of the lesion was carried. Results & Conclusions: Microscopic examination revealed a fibrofatty tissue seat of a tumoral proliferation made of spans and cords, of carcinomatous cells with moderate atypia showing some mitosis figures. The stroma is fibrous. Immunohistochemical studies showed positive immunoreactivity to pancytokeratin, estrogen receptor, progesterone receptor and HER-2, the results were in favor of a metastatic breast carcinoma. In summary, In the case of a metastatic orbital tumor, breast cancer should be considered as a possible source, especially in elderly women. Integrating the clinical information with histopathological findings is warranted.

Lymphoblastic lymphomas are immature lymphoid malig‐ nancies accounting for approximately 30% of non Hodgkin lym‐ phoma in children. Most of these neoplasms originate from T cell precursors while less than 25% of them originate from B lymphoblasts [1]. The most commonly involved sites are bone (26%) followed by skin or subcutaneous tissue (23%). On histol‐ ogy and immunohistochemistry, lymphoblasts in B Lymphoblas‐ tic Lymphoma (BLL) and B lymphoblastic leukaemia share the same features [2]. However, they represent different diseases with distinct molecular alterations [1]. Herein, we describe a case of BLL in a 2-year-old child presenting as a paravertebral mass, including the clinical and histopathological features with a review of the current literature. Abstract

Le choristome est une masse d’histologie normale dans une localisation anormale. Le choristome kystique est rarement rapporté dans la région de la tête et du cou. Les masses cervicales kystiques du nouveau-né évoquent avant tout un lymphangiome kystique. Nous rapportons un cas de choristome congénital cervical kystique mimant cliniquement et radiologiquement un lymphangiome kystique. Le choristome congénital kystique cervical est une lésion extrêmement rare rapportée surtout chez le nouveau-né. Les tissus le constituant sont très variés. Son diagnostic doit être évoqué à l’imagerie et confirmé par l’examen histopathologique. Le traitement est l’exérèse chirurgicale complète.

INTRODUCTION:Choristoma is a mass presenting normal histology, but in an abnormal location. Cystic choristoma is rarely reported in the head and neck region. Neonatal cystic masses in the neck suggest usually correspond to a diagnosis of cystic lymphangioma. CASE REPORT:We report a case of a congenital cystic choristoma of the neck clinically and radiologically mimicking cystic lymphangioma. DISCUSSION:Congenital cystic choristoma is an extremely rare lesion, essentially described in neonates, composed of various types of tissues. The diagnosis of congenital cystic choristoma may be suggested on imaging and must be confirmed by histopathological examination. Treatment consists of complete surgical resection.

The importance of methanotrophic microorganisms in the sediment and water column for balancing marine methane budgets is well accepted. However, whether methanotrophic populations are distinct for benthic and pelagic environments or are the result of exchange processes between the two remains an area of active research. We conducted a field pilot study at the Rostocker Seep site (Coal Oil Point seep field, offshore California, USA) to test the hypothesis that bubble-mediated transport of methane-oxidizing microorganisms from the sediment into the water column is quantifiable. Measurements included dissolved methane concentration showed a strong influence of methane seepage on the water-column methane distribution with strongly elevated sea surface concentrations with respect to atmospheric equilibrium (saturation ratio ~17,000%).Using Catalyzed Reporter Deposition Fluorescence In Situ Hybridization (CARD FISH) analysis, aerobic methane oxidizing bacteria (MOB) were detected in the sediment and the water column, whereas anaerobic methanotrophs (ANME-2) were detected exclusively in the sediment. Critical data for testing the hypothesis were collected using a novel bubble catcher that trapped naturally emanating seep gas bubbles and any attached particles approximately 15 cm above the seafloor. Bubble catcher experiments were carried out directly above a natural bubble seep vent and at a nearby reference site, for which an “engineered” nitrogen bubble vent without sediment contact was created. Our experiments indicate the existence of a “Bubble Transport Mechanism”, which transports MOB from the sediment into the water column. In contrast, ANME-2 were not detected in the bubble catcher. The Bubble Transport Mechanism could have important implications for the connectivity between benthic and pelagic methanotrophic communities at methane seep sites.

La fistule omphalo-mésentérique est une anomalie congénitale exceptionnelle en rapport avec la persistance complète du canal omphalo-mésentérique sur tout son trajet. Le diagnostic est posé par les données cliniques et la fistulographie sans avoir recours à d’autres examens complémentaires. Bien qu’une faible proportion de cette malformation se complique, le traitement chirurgical précoce est nécessaire.

La tuberculose occupe une place non negligeable dans les infections survenant au cours de certains cancers notamment les lymphomes. Dans certains cas le tableau clinique est evocateur d’une tuberculose, mais dans la majorite des cas il existe une symptomatologie non evocatrice. Les auteurs rapportent un cas de tuberculose associe un lymphome gastrique de Malt; ils mettent l’accent sur l’interet de la recherche d’une telle lesion difficilement accessible a la biopsie qui seule permet d’aboutir au diagnostic par le biais de l’examen anatomo-pathologique.

Eosinophilic esophagitis is a chronic allergic disease, recently described. The first reports date from 1977. Since, several other reports have been published. Eosinophilic esophagitis affects patients of all ages. In adults, the most characteristic symptom is intermittent dysphagia. In children, the symptoms can be similar to those of gastroesophageal reflux disease. The diagnosis of eosinophilic esophagitis is made when characteristic histological features are found in a setting of esophageal symptoms combined with endoscopic findings seen on the esophageal mucosa. The histological diagnosis requires multiples biopsies of the esophagus and remains mandatory to rule out other differential diagnosis and to order a specific treatment of this disease.We report a case of a 2 - year- old child with history of dysphagia. The diagnosis of eosinophilic esophagitis was established with the demonstration of a dense eosinophilic infiltrate of the esophageal mucosa at the histopathologic examination of esophageal biopsies.In this report, we present pathologists, gastroenterologists and pediatricians with simple and practical information for the biopsy-based histopathologic diagnosis of eosinophilic esophagitis.

Le tératome intrarénal est une tumeur extrêmement rare. Peu de cas ont été publiés dans la littérature médicale. Dans sa localisation rénale, le diagnostic de tératome est rarement évoqué en préopératoire. Ses signes cliniques et radiologiques étant peu spécifiques, le diagnostic final est souvent confirmé par l’étude anatomopathologique. Nous rapportons le cas d’un tératome kystique de localisation intrarénal chez un nourrisson de cinq mois. Une exérèse radicale de sa tumeur intrarénale a été réalisée. Devant la suspicion de tumeur de Wilms rénale, une chimiothérapie était administrée en préopératoire. La chirurgie est le traitement de choix du tératome intrarénal. Il n’est en général pas sensible à la chimiothérapie. Cela est dû au caractère mature et bien différencié des tissus tumoraux qui le constituent. Pour le chirurgien et le pathologiste pédiatres, ce diagnostic doit toujours être présent à l’esprit devant une masse rénale kystique pour éviter une chimiothérapie nocive pour ces jeunes patients.

L’oesophagite à éosinophiles est une pathologie chronique allergique rare, de description récente. Les premiers cas ont été publiés en 1977. Depuis, l’entité est de plus en plus rapportée dans la littérature médicale.

Blackbrush is a dominant shrub species in the transition zone between North American warm and cold deserts. Its seeds are dormant at dispersal and lose dormancy in response to moist chilling. Seeds from warmer low-elevation habitats have shorter chilling requirements and a higher optimum chilling temperature than those from colder habitats where winter snow regularly occurs. This ecotypic variation functions to time germination optimally in habitats with contrasting chilling regimes. Regulation of germination phenology is an important feature of the life history of this ecotonal species, which must be able to migrate elevationally through recruitment from seed in response to long-term climatic shifts in order to survive.

We report on a rare case of botryoid Wilms tumor extending into the duodenum. This uncommon macroscopic form of nephroblastoma consists entirely of a polypoid renal intrapelvic mass. The main differential diagnosis of this unusual tumor is botryoid rhabdomyosarcoma. A 14-month-old boy presented with a painful abdominal mass. Radiology revealed a large heterogeneous mass in the renal calyx, protruding into the ureter. A right radical nephroureterectomy was carried out. The tumor was found to extend into the 2nd portion of the duodenum. The pathologic diagnosis was mixed type nephroblastoma, SIOP 2001 stage III. The patient was given a course of postoperative chemotherapy. No local recurrence or metastatic spread has been detected after 2 years. Only few such cases have been previously reported, some of them extending into the bladder. To our knowledge, botryoid nephroblastoma has not previously been described as extending into the digestive system. (C) 2010 Elsevier Masson SAS. All rights reserved.

Nous rapportons l’observation d’un néphroblastome botryoïde étendu au duodénum. C’est une forme macroscopique inhabituelle du néphroblastome se développant essentiellement au niveau des cavités excrétrices sous l’aspect de végétations polypoïdes. Cette forme pose un problème de diagnostic différentiel avec le rhabdomyosarcome botryoïde. Le patient était un nourrisson de 14 mois admis pour une masse abdominale douloureuse. L’exploration radiologique mettait en évidence une tumeur rénale droite hétérogène occupant les cavités pyélocalicielles. La dissection chirurgicale révélait une extension de la tumeur à la 2e portion duodénale. L’examen anatomopathologique permettait de faire le diagnostic d’un néphroblastome botryoïde mixte de stade III selon la classification de la Société internationale d’oncologie pédiatrique (SIOP) 2001. Le patient recevait un traitement analogue à celui de la forme classique du néphroblastome. Plusieurs cas de néphroblastome botryoïde ont été rapportés dans la littérature, avec une extension à la vessie décrite dans certains cas. À notre connaissance, il n’a pas été décrit de néphroblastome botryoïde avec extension au tube digestif.

Le chondrosarcome mésenchymateux extrasquelettique est une tumeur rare des parties molles distincte sur le plan clinique, histologique, immunohistochimique et évolutif. Nous rapportons l’observation d’un homme de 44 ans présentant un nodule cervical asymptomatique depuis plusieurs années dont la taille aurait augmenté il y a deux ans. Une première biopsie a été réalisée et a conclu au diagnostic erroné de tumeur mixte des glandes salivaires. Une exérèse chirurgicale de la lésion était réalisée, suivie par trois récidives locales. Après la quatrième récidive, l’examen histopathologique avec étude immunohistochimique permettait de porter le diagnostic de chondrosarcome mésenchymateux extrasquelettique. Une radiothérapie et une chimiothérapie adjuvantes ont été délivrées. L’évolution était marquée par la survenue de métastases cutanée et vertébrale.