Objective To analyze the abnormal factors of the disorder status of calcium-phosphorus metablism in maintenance hemodialysis patients.Methods Serum calciun,serum phosphorus,calcium-phosphorus product and iPTH were detected in 130 patients with maintenance hemodialysis,and compared with the indicators of K/DOQI2003 and KDIGO2009 guidelines.Results Eligibility rate about serum calcium and phosphorus and multiplication and the level of intact parathyroid hormone were 48.12%,48.23%,78.75%,20.28% respectively by the indicators of K/DOQI2003 guidelines.There were 47.71%,28.74%,38.30% respectively by the indicators of KDIGO2009 guidelines.The level of serum phosphorus was lower in patients whose blood flow over 300mL/min than patients whose blood flow less than 300mL/min(t=2.892,P<0.05).The level of serum calciun,calcium-phosphoris product and PTH were higher in patients whose hemodialysis vintage over 3 years than patients whose hemodialysis vintage lower 3 years(t=2.479,5,681,3.012,P<0.05).The level of serum phosphorus and calcium-phosphoris product were lower in patients whose age over 50 years than patients whose age lower 50 years(t=2.212,3.367,P<0.05).Conclusion There is abnormal calcium and phosphorus metabolism in the patients with maintenance hemodialysis,which don′t reach the K/DOQI and KDIGO guidelines.As the dialysis time increase,the abnormal mineral metabolism become more obviously.
210 MHD patients were retrospectively analyzed for the basic information in the hemodialysis( HD) cen-ter, including the vascular access( VA) options and the incidence of complications with AVF. The patients were as-signed into two groups, i. e. the AVF and the temporary central venous catheter( TCVC) , and the information of ed-ucation, economic status and AVF life were compared. The most popular VA at the beginning of HD was TCVC (72. 9%), then AVF(25. 7%). AVF was the main VA of MHD patients (96. 2%), but the proportion of the first HD with AVF (25. 7%) was still lower than the proportion of the guide. The patients with preparation of AVF in advance were positively correlated with their cultural education level and economic status, which had fewer long-term complications than others. There was a statistically significant difference (P<0. 05),while no difference asso-ciated with the patients′gender, age, primary disease and fistula blood flow was found.
Objective The psychometric hepatic encephalopathy scale (PHES),including five psychometric tests,is a standard for the diagnosis of minimal hepatic encephalopathy (MHE) and enjoys predictive value of overt hepatic encephalopathy (OHE).We investigate whether a simplified PHES is as useful as the whole PHES.Methods Seventy consecutive hepatitis B cirrhotic patients without OHE,admitted to our hospital from October 2012 to June 2013,and other 72 healthy volunteers were chosen in our study.PHES was performed in both groups.Expected normal reference value formula were established based on the 5 psychometric tests in healthy controls,and backward logistic regression was performed by eliminating stepwise variables of PHES to get a simplified PHES (SPHES).Then,SPHES was performed on the 70 patients and followed up for a year to detect the prevalence rate of MHE and OHE.Results PHES was easily influenced by age and educational level.In patients with liver cirrhosis,44.29% patients (31/70) had MHE based on PHES and 41.43% (9/70) had MHE based on SPHES,without significant differences (P>0.05).According to the follow-up study,21 patients developed OHE; the number of developing OHE showed no significant difference between MHE patients dignosed by PHES and SPHES (P>0.05).Conclusion SPHES is as good as PHES in diagnosing MHE and predicting the occurrence of OHE,which consumes less time and is more suitable for clinical screening.