PurposeWith the improvement of consumers' health consciousness, healthy food has attracted great attention in daily consumption. Previous research into the sense of power often distinguishes it into high and low level, ignoring the impact of different construal of power on consumption behaviors. This article divides power into dual construal (responsibility vs opportunity) and aims to examine the differential impacts of the construal of power on healthy food preference.Design/methodology/approachTwo pretests and three formal experiments were conducted to examine the effect of the construal of power on the consumer's healthy food preference, the mediation of self-discipline perception and the moderation of the relative strength of prevention over promotion focus (i.e. RSPPF).FindingsResults indicate that individuals who construe power as responsibility (vs opportunity) exhibit higher self-discipline perception, which in turn leads to greater healthy food preference. However, the main effect above can be weakened among the low-power group. Moreover, the above mediating effect of self-discipline perception is stronger for individuals with higher RSPPF.Originality/valueFirst, based on the binary-construal perspective, this study refines the classification of high power and introduces it into the antecedent research of healthy food preference. Second, this paper reveals the self-discipline perception as the inner mechanism underlying the effect of the construal of power on healthy food preference, while RSPPF as the boundary condition for this mediating mechanism. Moreover, this research also provides practical implications for healthy food enterprises that the construal of power, self-discipline perception and regulatory focus should be taken into consideration in advertising design and healthy product promotion.

Previous research has suggested that social exclusion could strengthen consumers' reliance on feelings versus reasons to evaluate a product. This research concentrates on the moderating effect of culture on consumers' responses to social exclusion. Results show that under individualism (collectivism) culture, social exclusion leads to a greater choice preference for advertisement with superior feelings- (reasons-) based product attributes, compared with social inclusion. Moreover, we find that the interplay between culture and social exclusion is discrepant under two types of social exclusion (i.e., being socially ignored-feeling invisible, and being socially rejected-feeling isolated). This research provides a new cultural perspective on the impact of social exclusion on advertisement persuasion and offers actionable implications for managers to strategically design advertisements to enhance the persuasiveness.

This study examined the relationship between authoritarian leadership and employees' unsafe behaviors, and the mediating roles of organizational cynicism and work alienation. Questionnaires were distributed to first-line production employees, and structural equation modeling was employed to test the hypotheses. The results showed that organizational cynicism mediated the relationship between authoritarian leadership and employees' unsafe behaviors. Furthermore, authoritarian leadership was related to employees' unsafe behaviors through organizational cynicism first and then work alienation. The theoretical implications of these findings for advancing the research and practical approaches to reduce employees' unsafe behaviors are discussed.

目的:描述急性早幼粒细胞白血病(acute promyelocytic leukemia,APL)合并髓细胞肉瘤(myeloid sarcoma,MS)的诊断、治疗和预后.方法:报告2例APL合并MS患者的诊断和治疗经过,并结合文献进行分析.结果:病例1是以MS为首发表现的APL.右侧胸壁肿物穿刺活检结合免疫组织化学检测结果符合MS.给予维A酸、三氧化二砷联合伊达比星化疗1个周期后,患者右侧胸壁肿物消失,骨髓检查显示疾病缓解,之后维持治疗至2018年5月.病例2是确诊APL 25年后髓外复发时合并MS.胸骨旁肿块穿刺活检结合免疫组织化学检测结果符合MS.给予维A酸联合伊达比星和阿糖胞苷方案化疗1个周期,胸骨软组织肿块缩小,患者出院后自行停用维A酸,之后未再治疗,电话随访患者于2017年4月3日死亡.结论:APL合并MS发病率低,但恶性程度高,维A酸、三氧化二砷联合化疗有效,但整体预后较差.

Objective To investigate the clinical significance of serum levels of lactate dehydrogenase( LDH) andβ2?micro?globulin(β2?MG) in diffuse large B?cell lymphoma(DLBCL). Methods The serum levels of LDH and β2?MG of 58 patients with DLBCL were measured by rate method and radioimmunoassay. Besides, the clinicopathological characteristics of the patients such as gender, age, B symptoms, clinical stages, ECOG score of performance status( ECOG?PS) and bone marrow invasion were summarized and anylyzed. Meanwhile, the association between the level change of LDH and β2?MG after chemotherapy and therapeutic effectiveness was also evaluated. Results The levels of LDH andβ2?MG in the advanced stage group,ECOG≥2 group, bone marrow invasion group were significantly higher than those of their counterpart (P<0?05).The level of β2?MG in aged over 60 patients was higher than that of younger ones ( P<0?05) ,but there was no statistical significance in the LDH level( P>0?05) . The level of LDH in B symptoms group was higher than that of without B symptoms( P<0?05) ,but there was no statistical significance in the β2?MG level ( P>0?05) . There was no statistical significance about LDH andβ2?MG levels in gender( P>0?05) . The levels of LDH andβ2?MG in positive response group significantly decreased after chemotherapy ( P<0?05) . Conclusion LDH andβ2?MG can be taken as indica?tors in classifying the clinical phase and judging whether there is bone marrow infiltration or not, and evaluating the chemotherapeutic effectiveness of DLBCL patients.

慢性淋巴细胞白血病(CLL)是一种常见的血液系统恶性疾病,发病的根本原因至今尚未明确.近年来的研究表明肿瘤微环境对于 CLL细胞的生长和生存起了重要的作用.免疫调节药物反应停及其类似物,能以肿瘤细胞微环境为靶向,通过下调某些细胞因子、调节免疫效应细胞而抑制肿瘤细胞生长.一些临床试验正在评估这些药物治疗CLL的疗效.