M E Dodzin | AMiner学者主页

1[L-Glutamate Oxidase from Streptomyces Cremeus 510 MGU: Effect of Nitrogen Sources on Enzyme Secretion].

K A Vinogradova, I,T S Sharkova,M E Dodzin,V N Maksimov

Effect of nitrogen sources (organic complexes and mineral salts) on L-glutamate oxidase synthesis by Streptomyces cremeus 510 MGU was studied. Optimal enzyme production was not provided by any single nitrogen source. The most effective combination of nitrogen sources (soy flour, peptone, ammonium sulfate) was elaborated by the mathematical planning method. The results of experiment allowed to enhance biosynthesis of extracellular L-glutamate oxidase to 2.4-2.6 U/mL. It was shown that L-glutamate oxidase of Streptomyces cremeus 510 MGU is highly specific to substance and is stable during storage of filtrated culture with pH 6.8-9.0.

2003PubMed（2003）引用：23

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2[L-Glutamate Oxidases from Streptomyces. Properties of the Enzymes, Their Production and Methods of Determining Their Activity].

K A Vinogradova,I B Kotova,M E Dodzin

1999PubMed引用：22

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3L-глутаматоксидазы Стрептомицетов. Свойства Ферментов, Их Получение И Методы Определении Активности

К.А. Виноградова, Irina Kotova,М.Е. Додзин

1999Antibiot Khimioter = Antibiotics and Chemotherapy（1999）

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4Обзор. L-глутаматоксидазы Стрептомицетов. Применение В Клинической И Фундаментальной Медицине

К.А. Виноградова,М.Е. Додзин

1999Antibiot Khimioter = Antibiotics and Chemotherapy（1999）

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5L-глутаматоксидазы стрептомицетов. Свойства ферментов, их получение и методы определении активности

к а виноградова,и б котова,м е додзин

1999引用：23

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6[Streptomyces L-glutamate Oxidase: Use in Clinical and Fundamental Medicine].

K A Vinogradova,M E Dodzin

1999Antibiotiki i khimioterapiia = Antibiotics and chemoterapy sic（1999）

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7Новые Продуценты L-глутаматоксидазы – Streptomyces Litmocidini И Streptomyces Cremeus

М.Е. Додзин, Katerina A. Vinogradova, Irina Kotova

1998Antibiot Khimioter = Antibiotics and Chemotherapy（1998）

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8[Novel L-glutamate oxidase producing organisms: Streptomyces litmocidini and Streptomyces cremeus].

M E Dodzin,K A Vinogradova,I B Kotova

Two novel strains i.e. Streptomyces cremeus 510 and Streptomyces litmocidini 447 producing L-glutamate oxidase were isolated from soil samples and identified. Mathematical design of the experiments made it possible to optimize the fermentation medium composition which provided at least a 5-fold increase of the strain L-glutamate oxidase activity by comparison with the initial activity in the standard medium.

1998Antibiotiki i khimioterapii͡a = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoĭ i mikr...（1998）引用：22

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9Новые продуценты L-глутаматоксидазы – Streptomyces litmocidini и Streptomyces cremeus

м е додзин,к а виноградова,и б котова

1998引用：22

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