Background and Objective: Acute Renal Failure or disease (ARF) is a complicated disorder that causes a fast reduction in kidney function and anemia is a common feature of this disease.This study aimed to evaluate the anemia situation in patients with acute renal failure among men and women.Materials and Methods: This case study was conducted on 56 patients with acute renal failure attending DEE Medical Center, Buruku, Jos, Plateau State Nigeria, from January-September, 2019.Initially, two separate blood samples were taken from each patient, 2 mL uncoagulated sample harvest for biochemical assay and EDTA anticoagulated whole blood sample for hematocrit value.Serum was used to determine the level of urea, creatinine and hematocrit value was done with EDTA anticoagulated samples by hematocrit centrifuge.The values obtained in urea and creatinine were divided into three groups: low, moderate and high, data obtained were analyzed by SPSS software.Results: Generally, the study revealed the anemic condition of all the acute renal disease patients irrespective of gender (p<0.05).However, it was discovered that the mean hematocrit value of females (22.2+3.3) was higher than of males (19.8+2.5).Conclusion: It was discovered that the severity of anemia in acute renal disease in men was as a result of the effect of the disease on testosterone level synthesized in the kidney, therefore, it is recommended that testosterone can be used as alternative or complementary for erythropoietin to boost up hematocrit value in severely anemic patients and management of acute renal failure in men.
Haemoparasites are blood parasites which are endemic in Nigeria and can cause serious morbidity in humans. Understanding patterns of hemoparasites infections in humans can therefore inform about emerging diseases risks, especially in the light of climatechange. Infections due to these parasites can be asymptomatic; this asymptomatic infection has been one of the factors which has maintained transmission of these parasites, through many ways, including blood donation and transfusion. The effects of heamoparasites on donors age, sex, blood group and PCV within Plateau State, Nigeria, was investigated. Five hundred and twelve donors were selected by means of a random sampling method and their blood samples collected. Serological assay was done using rapid test kits to check for presence of antibodies (in the case of microfilariae) or antigens (in the case of Plasmodium) to the different haemoparasites. ELISA technique was used for the microfilariae investigation. Thick and thin films were made from each blood sample on grease-free slides, allowed to dry and stained by 3% Giemsa solution for 45 min for microscopy. Results shows 144 (28.1%) prevalence of haemoparasites and 368 (71.9%) non infection; 121 (23.6%) of the population were infected with Plasmodium falciparum; 11 (2.1%) were infected with Plasmodium malariae; 7 (1.4%) were infected with Trypanosoma brucei gambiense; 5 (1%) were infected with microfilariae, 4 (0.8%) of the 1% were unsheathed and identified to be Mansonell aperstans, while 1 (0.2%) were sheathed and identified to be Loa loa. Most blood group types were susceptible with the exception of only A- and AB- to haemoparasitic infections. Age-group (33-45), lower PCV and males have more infections. The result of the study therefore stresses the need to screen blood for haemoparasites before transfusion to avoid the risk of emerging diseases.Keywords: Haemoparasites; blood donors; volunteer; National Blood Transfusion Service (NBTS)