Introduction:To support advance care planning (ACP), a conversation game, Anticip'action, and a connected 3-step ACP intervention using the game were developed. This study assessed the acceptability, feasibility, and effect of the intervention with patients undergoing dialysis at a tertiary hospital. Methods:Dialysis nurses received a 10-hour training in ACP and use of the card game Anticip'Action. All patients on dialysis in the nephrology division were eligible. Acceptability and feasibility were assessed using questionnaires and note taking. Effect was assessed using pre-post number of advance directives (ADs), number of patients designating a surrogate, quality of written ACP documentation, patients' responses to the 9-items ACP Engagement Survey, and patients' assessment of their ACP documentation. Results:Twelve nurses conducted ACP interventions. Thirty-three patients (87% of eligible patients) accepted to be included, 25 (75%) started the ACP intervention, 23 completed it, and 18 answered all questionnaires. 5 withdrawals were due to premature death. Nurses and patients rated the training, the intervention and the card game as good and highly acceptable: mean scores ranged from 2.87 to 4.17 on a 5-point Likert scale questions. Organizational difficulties were reported by nurses. Significant increases were observed on uploaded ADs (+ 30%), designated health care surrogates (+ 80%), patients reporting end-of-life planning actions (12/19), patients' engagement in ACP (+ 1.04 on 1-5 scale, P ≤ 0.001), quality of ACP documentation (+ 2.68 on a 1-5 scale, P ≤ 0.001), and patients' evaluation of their ACP documentation (3.44 ± 1.04 on 1-5 scale). Conclusion:The 3-step ACP intervention using Anticip'action showed good implementation potential in clinical context.

We use photoemission electron microscopy to measure the ferroelastic twin wall angles at the surface of CaTiO$_\mathrm{3}$(001) and deduce the strain ordering. We analyze the angular dependence of the photoelectron emission from different domain surfaces, each with their own characteristic tilt angle in the factory roof-like topography. By considering the surface topography as a field perturbation, the offset in the photoemission threshold can be directly related to the tilt angles. With knowledge of the symmetry allowed twin walls we quantify twin topography between 179.1{\deg} to 180.8{\deg}.

Background Because of COVID-19, the 2020 written medical examinations were replaced by mandatory formative online assessments. This study aimed to determine students’ performance, self-assessment of performance, and perception about the switch from a summative to a formative approach. Methods Medical students from year 2 to 5 (n=648) were included. They could repeat each test once or twice. They rated their performance after each attempt and were then given their score. Detailed feedback was given at the end of the session. An online survey determined medical students’ perception about the reorganization of education. Two items concerned the switch from summative to formative assessments Results Formative assessments involved 2385 examinees totaling 3197 attempts. Among examinees, 30.8% made at least 2 attempts. Scores increased significantly at the second attempt (median 9.4, IQR 10.8), and duration decreased (median -31.0, IQR 48.0). More than half of examinees (54.6%) underestimated their score, female students more often than male. Low performers overestimated, while high performers underestimated their scores. Students approved of the switch to formative assessments. Stress was lessened but motivation for learning decreased. Conclusions Medical students’ better scores at a second attempt support a benefit of detailed feedback, learning time and re-test opportunity on performance. Decreased learning motivation and a minority of students repeating the formative assessments point to the positive influence of summative assessment on learning.

Background We have developed 1) a card game (Anticip'action) to help patients clarify their values and priorities in life and develop aligned action plans, and 2) a three step ACP intervention involving the use of the game to be routinely implemented in the nephrology unit. We will present preliminary results of an ongoing study (start date: January 2022; expected end: sept 2023) designed to 1) evaluate the acceptability and feasibility of this intervention, from patients and health professionals' points of view, and 2) observe the effect of the intervention on ACP documentation in patient's medical record. Method We include patients on dialysis (with or without transplant project) & nurses working in the nephrology unit who are responsible for conducting ACP with those patients. Two ACP discussion sessions with the use of the game Anticip'action are offered by trained nurses (n=10) to their patients (expected n=30), followed by an ACP consultation, involving the patient, the nurse, and a nephrologist. During discussions, the patients' electronic medical record is updated. We record inclusion and dropout rates, difficulties encountered, evaluate the pre-post quality of information in patients' medical record, and conduct semi-structured interviews with 10–15 patients, one focus group with the nurses and one with the interprofessional team. Results By the time of the conference, we will have collected enough data to present substantial preliminary results about the number of nurses trained, the number of patients included, dropouts in both groups, barriers encountered during the recruitment and ACP procedure (e.g. nurses lack of compliance to the procedure, and patients' death before completion of the process are difficulties we can already highlight), qualitative feed-backs from patients and nurses. Conclusions This study will help us assess the feasibility of our ACP procedure, identify what can be improved, and provide background data for future efficacy studies.

A person at the end of life may present uncomfortable symptoms becoming refractory to an adequate treatment. In this case, the initiation of palliative sedation is indicated. Most sedated inpatients die outside a specialized palliative care unit. Palliative sedation must be initiated and adapted according to the best clinical practices. This article describes the processes associated with palliative sedation in a hospital unit.Une personne en fin de vie peut présenter des symptômes inconfortables devenant réfractaires à un traitement adéquat. Dans ce cas, l’instauration d’une sédation palliative est indiquée. La majorité des patients hospitalisés et sédatés décèdent en dehors d’une unité spécialisée de soins palliatifs. La sédation palliative doit pouvoir être introduite et adaptée selon les règles de bonnes pratiques. Cet article traite des processus liés à la sédation palliative en unité hospitalière.

A person at the end of life may present uncomfortable symptoms becoming refractory to an adequate treatment. In this case, the initiation of palliative sedation is indicated. Most sedated inpatients die outside a specialized palliative care unit. Palliative sedation must be initiated and adapted according to the best clinical practices. This article describes the processes associated with palliative sedation in a hospital unit.

Background: Because of COVID-19, the 2020 written medical examinations were replaced by mandatory formative online assessments. This study aimed to determine students’ performance, self-assessment of performance, and perception about the switch from a summative to a formative approach. Methods: Medical students from year 2 to 5 (n=648) were included. They could repeat each test once or twice. They rated their performance after each attempt and were then given their score. Detailed feedback was given at the end of the session. An online survey determined medical students’ perception about the reorganization of education. Two items concerned the switch from summative to formative assessments Results: Formative assessments involved 2385 examinees totaling 3197 attempts. Among examinees, 30.8% made at least 2 attempts. Scores increased significantly at the second attempt (median 9.4, IQR 10.8), and duration decreased (median -31.0, IQR 48.0). More than half of examinees (54.6%) underestimated their score, female students more often than male. Low performers overestimated, while high performers underestimated their scores. Students approved of the switch to formative assessments. Stress was lessened but motivation for learning decreased. Conclusions: Medical students’ better scores at a second attempt support a benefit of detailed feedback, learning time and re-test opportunity on performance. Decreased learning motivation and a minority of students repeating the formative assessments point to the positive influence of summative assessment on learning.

Background: Because of COVID-19, the 2020 written medical examinations were replaced by mandatory formative online assessments. This study aimed to determine students’ performance, self-assessment of performance, and perception about the switch from a summative to a formative approach. Methods: Medical students from year 2 to 5 (n=648) were included. They could repeat each test once or twice. They rated their performance after each attempt and were then given their score. Detailed feedback was given at the end of the session. An online survey determined medical students’ perception about the reorganization of education. Two items concerned the switch from summative to formative assessments Results: Formative assessments involved 2385 examinees totaling 3197 attempts. Among examinees, 30.8% made at least 2 attempts. Scores increased significantly at the second attempt (median 9.4, IQR 10.8), and duration decreased (median -31.0, IQR 48.0). More than half of examinees (54.6%) underestimated their score, female students more often than male. Low performers overestimated, while high performers underestimated their scores. Students approved of the switch to formative assessments. Stress was lessened but motivation for learning decreased. Conclusions: Medical students’ better scores at a second attempt support a benefit of detailed feedback, learning time and re-test opportunity on performance. Decreased learning motivation and a minority of students repeating the formative assessments point to the positive influence of summative assessment on learning.

A two-dimensional imaging spin-filter for photo-emission electron microscopy is described. The spin-filter is capable of imaging the electron spin polarization of either real space or momentum space electron distributions. As a scattering target either Au/Ir(001) comes into use, where spin sensitivity results from using spin-orbit scattering or Fe(001)-p(1×1)O that exploits exchange interaction. Both scattering targets were characterized with respect to their working points and Sherman function in a separate setup. Spin-polarization images of secondary electrons from the magnetic domains of a poly-crystalline iron sample are shown using both scattering targets. Images with a spin-filter using Au/Ir(001) show more than 104 discrete detection channels which increases the effective two-dimensional figure-of-merit (FoM) of this spin-filter by four orders of magnitude compared to single-channel spin detectors. Using the exchange scattering target two spin-components have been imaged for the first time. A method to detect all three spin-components is also outlined.

The COVID-19 pandemics has deeply impacted academic teaching and forced a complete shift to distance learning formats during the first and second waves. Medical education, among other professional training programs, relies also on practical and clinical immersion, while some of these clinical activities had to be postponed. This article analyzes how one medical school was able to maintain its teaching while ensuring clinical training and taking into account the psychological impact imputed to the lockdown. It also highlights the learning opportunities and unprecedented life experiences contributing to the training of tomorrow's physicians.

The COVID-19 pandemics has deeply impacted academic teaching and forced a complete shift to distance learning formats during the first and second waves. Medical education, among other professional training programs, relies also on practical and clinical immersion, while some of these clinical activities had to be postponed. This article analyzes how one medical school was able to maintain its teaching while ensuring clinical training and taking into account the psychological impact imputed to the lockdown. It also highlights the learning opportunities and unprecedented life experiences contributing to the training of tomorrow's physicians.La pandémie Covid-19 a imposé à l’enseignement, notamment universitaire, le passage complet à des formats à distance durant les première et deuxième vagues. La formation médicale, entre autres, se caractérise par une forte composante pratique et une immersion clinique. Cet article analyse comment une faculté de médecine a pu maintenir son enseignement en assurant au mieux une formation clinique, en tenant compte autant que possible des conséquences psychologiques objectivées par des enquêtes facultaires. Il valorise également les opportunités d’apprentissage et les expériences inédites amenées par la pandémie et leur intégration dans la formation des médecins de demain.

En raison d’une morbidité et d’une mortalité importantes des patients dialysés, avec une espérance de vie limitée, il est essentiel d’établir un projet de soins anticipé afin de connaître leurs valeurs et leurs préférences en termes de traitement, et ainsi respecter leur autonomie. Toutefois, cette démarche est rarement effectuée, en raison des difficultés à parler de fin de vie, tant pour les patients que pour les professionnels de santé. L’utilisation de « jeux sérieux », sous forme de jeux de cartes, s’est montrée prometteuse pour soutenir la mise en place d’un projet de soins anticipé. Nous présentons dans cet article le processus de développement d’une intervention de projet de soins anticipé auprès de patients dialysés par l’intermédiaire d’un jeu de cartes (le Go Wish), dans le service de néphrologie des Hôpitaux Universitaires de Genève.

Hiccups are a rare but potentially debilitating side effect of opioid treatment, with only a handful of reported cases in the medical literature. The pathophysiological mechanism linking opioids and hiccups is unknown, and a lack of evidence exists concerning the optimal management of the condition. We report on a 64-year-old man diagnosed with advanced renal cancer and painful osteolytic metastases, presenting persistent hiccups while on opioid treatment. Hiccups recurred after multiple challenges with codeine, morphine and hydromorphone on separate occasions. Hiccups ceased only after opioid discontinuation, although various pharmacological treatments were tried to shorten the duration of hiccups. Eventually, fentanyl was introduced and was well tolerated by the patient, without any recurrence of hiccups. The chronological correlation between opioid initiation and the onset of hiccups, as well as opioid discontinuation and the termination of hiccups leads to the conclusion that a causal role of codeine, morphine and hydromorphone in this occurrence is likely. Individual susceptibility probably plays a central role in the development of opioid-related hiccups. Opioid rotation is a promising strategy in the management of opioid-related hiccups, particularly when the mere discontinuation of the opioid is not a viable option, such as in the oncology and palliative care field.

Following the therapeutic progress of the last decades, patients suffering from chronic heart failure (HF) are living longer than ever before. However, recovery from a HF syndrome remains rare and patients more often have to live with chronic HF which considerably impacts their quality of life. For several years, national and international cardiology societies have recommended the early integration of palliative care for HF patients. Although the impact of palliative care on the quality of life, depression and general symptom management of patients with HF has now been clearly established, its implementation is still scarce. The objective of this review is to highlight recommendations and models of care for the implementation of palliative care for patients with HF.Grâce aux progrès thérapeutiques des dernières décennies, les personnes atteintes d’insuffisance cardiaque (IC) ont une espérance de vie qui augmente. Cependant, la guérison du syndrome d’IC reste rare et le plus souvent les patients vivent avec une IC chronique ayant un impact considérable sur leur qualité de vie. Depuis de nombreuses années, les recommandations nationales et internationales de cardiologie préconisent une prise en charge palliative intégrée et précoce de ces patients. Bien que son impact sur la qualité de vie, la dépression et la gestion globale des symptômes des patients souffrant d’IC soit maintenant clairement démontré, son implémentation dans la pratique reste insuffisante. L’objectif de cet article est de mettre en lumière les recommandations et modèles de prise en charge palliative pour les patients souffrant d’IC.

Pain, including chronic non-cancer pain (CNCP), is a common reason for primary care consultation. CNCP encompasses a heterogeneous group of patients, whose care is often complex. The increase in opioid prescription in Switzerland and worldwide is associated with CNCP, while opioid use for this indication is debated. Several studies suggest a limited effect on pain and function, while adverse effects are frequent. This article aims to summarize what is known about opioid prescription for CNCP and international guidelines and highlight important aspects for the general practitioner.La douleur, dont la douleur chronique non cancéreuse (DCNC), est un motif de consultation très fréquent en médecine de premier recours. La DCNC regroupe des populations hétérogènes de patients dont la prise en charge est généralement complexe. L’augmentation de la prescription d’opiacés en Suisse et dans le monde concerne davantage les DCNC, alors que l’utilisation d’opiacés pour cette indication est controversée. Différentes études suggèrent que les effets bénéfiques sur la douleur et la fonctionnalité seraient limités contrairement aux effets secondaires relativement fréquents. Cet article a pour but de résumer l’état des connaissances sur la prescription d’opiacés pour les DCNC et les recommandations internationales pour fournir une aide pratique en médecine générale.

Due to the high morbidity and mortality with limited life expectancy of dialysis patients, it is essential to implement advance care planning in order to know patients' values and care preferences and respect their autonomy. However, advance care planning is rarely carried out, due to the difficulties in initiating end-of-life discussions, both by patients and healthcare professionals. The use of "serious games " in the form of card games has shown promise in supporting the implementation of advance care planning. In this article, we present the development process of an advance care planning intervention for dialysis patients using a card game (the Go Wish), in the Division of Nephrology of the University Hospitals of Geneva. (C) 2022 The Author(s). Published by Elsevier Masson SAS on behalf of Societefrancophone de nephrologie, dialyse et transplantation.

Le plan de soin anticipé permet de planifier à l’avance les objectifs de soins du patient en favorisant la communication interprofessionnelle. Un projet de recherche qualitative a été initié auprès des infirmières et des médecins en charge de patients qui pourraient bénéficier de soins palliatifs. L’utilisation du plan de soin anticipé a été proposée à la suite d’un sondage permettant d’évaluer les besoins en communication et de mesurer la facilité du dialogue autour des discussions d’attitude pour les patients atteints d’une maladie chronique évolutive.

Pain, including chronic non-cancer pain (CNCP), is a common reason for primary care consultation. CNCP encompasses a heterogeneous group of patients, whose care is often complex. The increase in opioid prescription in Switzerland and worldwide is associated with CNCP, while opioid use for this indication is debated. Several studies suggest a limited effect on pain and function, while adverse effects are frequent. This article aims to summarize what is known about opioid prescription for CNCP and international guidelines and highlight important aspects for the general practitioner.

Purpose: This report describes the essential steps in the development, implementation, evaluation and quality assurance of the written part of the Swiss Federal Licensing Examination for Human Medicine (FLE) and the insights gained since its introduction in 2011.Methods: Based on existing scientific evidence, international expertise, and experience gained from previous examinations, the FLE is developed by experts from all five medical faculties in Switzerland with the support of the Institute for Medical Education and is held simultaneously at five locations. The exam organisers document and review every examination held and continuously optimise the processes; they have summarised the results in this report.Results: The essential steps comprise the development, revision and translation of questions; construction of the exam and production of materials; candidate preparation; implementation and analysis. The quality assurance measures consist of guideline coherence in the development of the questions and implementation of the exam, revision processes, construction of the exam based on the national blueprint, multiphase review of the translations and exam material, and statistical analysis of the exam and the comments from candidates. The intensive collaboration, especially on the part of representatives from all the participating faculties and a central coordination unit, which provides methodological support throughout and oversees the analysis of the exam, has proven successful. Successfully completed examinations and reliable results in the eleven examinations so far implemented represent the outcomes of the quality assurance measures. Significant insights in recent years are the importance of appreciating the work of those involved and the central organisation of exam development, thus ensuring the long-term success of the process.Conclusion: Common guidelines and workshops, quality assurance measures accompanied by the continuous improvement of all processes, and appreciation of everyone involved, are essential to carrying out such an examination at a high-quality level in the long term.