Background: Population-based studies of childhood cancer incidence, survival and mortality make an important contribution to monitoring the successful implementation of new treatment guidelines and to understanding the epidemiology of these diseases.Methods: We analysed incidence and survival data for cancers diagnosed in children under 15 years of age in the Republic of Ireland during 1994-2000 (the first 7 years of National Cancer Registry coverage), and longer term mortality trends.Results: World age-standardised incidence rates in Ireland averaged 142 cases per million children per year, slightly higher than the European average and slightly lower than the US average, although differences varied by diagnostic group. Observed 5-year survival in Ireland (79% overall) was slightly higher than European and US averages, and was significantly higher for acute non-lymphocytic leukaemia (67%) and (compared with the USA) significantly lower for Hodgkin lymphoma (83%). No significant increases in incidence rates were evident from the available 7 years' data, either overall or for particular diagnostic groups. Rates of childhood cancer mortality have declined markedly since the 1950s.Conclusions: Data presented here are in line with other developed countries and suggest major improvements in treatment and consequent survival.

Crop ScienceVolume 45, Issue 3 p. 1166-1167 Registration Registration of 'Burton' Barley P. Bregitzer, Corresponding Author P. Bregitzer [email protected] USDA-ARS, 1691 S. 2700 W., Aberdeen, ID, 83210 Corresponding author ([email protected])Search for more papers by this authorD.W. Mornhinweg, D.W. Mornhinweg USDA-ARS, 1301 N. Western St., Stillwater, OK, 74075Search for more papers by this authorR. Hammon, R. Hammon Colorado State University, P.O. Box 20000-5028, Grand Junction, CO, 81502Search for more papers by this authorM. Stack, M. Stack Colorado State University, P.O. Box 233, Yellow Jacket, CO, 81335Search for more papers by this authorD.D. Baltensperger, D.D. Baltensperger University of Nebraska, 4502 Ave. I, Scotts Bluff, NE, 69361Search for more papers by this authorG.L. Hein, G.L. Hein University of Nebraska, 4502 Ave. I, Scotts Bluff, NE, 69361Search for more papers by this authorM.K. O'Neill, M.K. O'Neill New Mexico State University, 300 Navajo Rd., Farmington, NM, 87499Search for more papers by this authorJ.C. Whitmore, J.C. Whitmore University of Idaho, Tetonia, ID, 83436Search for more papers by this authorD.J. Fiedler, D.J. Fiedler USDA-ARS, 1691 S. 2700 W., Aberdeen, ID, 83210Search for more papers by this author P. Bregitzer, Corresponding Author P. Bregitzer [email protected] USDA-ARS, 1691 S. 2700 W., Aberdeen, ID, 83210 Corresponding author ([email protected])Search for more papers by this authorD.W. Mornhinweg, D.W. Mornhinweg USDA-ARS, 1301 N. Western St., Stillwater, OK, 74075Search for more papers by this authorR. Hammon, R. Hammon Colorado State University, P.O. Box 20000-5028, Grand Junction, CO, 81502Search for more papers by this authorM. Stack, M. Stack Colorado State University, P.O. Box 233, Yellow Jacket, CO, 81335Search for more papers by this authorD.D. Baltensperger, D.D. Baltensperger University of Nebraska, 4502 Ave. I, Scotts Bluff, NE, 69361Search for more papers by this authorG.L. Hein, G.L. Hein University of Nebraska, 4502 Ave. I, Scotts Bluff, NE, 69361Search for more papers by this authorM.K. O'Neill, M.K. O'Neill New Mexico State University, 300 Navajo Rd., Farmington, NM, 87499Search for more papers by this authorJ.C. Whitmore, J.C. Whitmore University of Idaho, Tetonia, ID, 83436Search for more papers by this authorD.J. Fiedler, D.J. Fiedler USDA-ARS, 1691 S. 2700 W., Aberdeen, ID, 83210Search for more papers by this author First published: 01 May 2005 https://doi.org/10.2135/cropsci2004.0461CVCitations: 22 Registration by CSSA. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Bregitzer, P. 2003. Resistance to Russian wheat aphid damage derived from STARS 9301B protects agronomic performance and malting quality when transferred to adapted barley germplasm. Crop Sci. 43: 2050–2057 http://doi.org/10.2135/cropsci2003.2050 Haley, S.D. 2004. Occurrence of a new Russian wheat aphid biotype in Colorado. Crop Sci. 44: 1589–1592 http://doi.org/10.2135/cropsci2004.1589 Hockett, E.A. 1985. Registration of 'Clark' barley. Crop Sci. 25: 197 http://doi.org/10.2135/cropsci1985.0011183X002500010049x Mornhinweg, D.W. 1995. a. Registration of STARS-9301B Russian wheat aphid resistant barley germplasm. Crop Sci. 35: 603 http://doi.org/10.2135/cropsci1995.0011183X003500020075x Mornhinweg, D.W. 1995. b. Inheritance of Russian wheat aphid resistance in spring barley. Crop Sci. 35: 1368–1371 http://doi.org/10.2135/cropsci1995.0011183X003500050018x Muir, C.E. 1973. Registration of 'Steptoe' barley. Crop Sci. 13: 770 http://doi.org/10.2135/cropsci1973.0011183X001300060064x Robertson, D.W. 1965. 'Colsess', 'Moravian', 'Munsing', and 'Otis' barleys. Crop Sci. 5: 197 http://doi.org/10.2135/cropsci1965.0011183X000500020042x Wells, S.A. 1973. 'Hector' barley. Can. J. Plant Sci. 53: 497 http://doi.org/10.4141/cjps73-095 Wesenberg, D.M. 1974. Registration of 'Klages' barley. Crop Sci. 14: 337 http://doi.org/10.2135/cropsci1974.0011183X001400020054x Wesenberg, D.M. 1991. Registration of 'Crystal' barley. Crop Sci. 31: 481 http://doi.org/10.2135/cropsci1991.0011183X003100020056x Citing Literature Volume45, Issue3May–June 2005Pages 1166-1167 ReferencesRelatedInformation

Regulation of cytosolic pH is vital for normal cellular function.Pathological microenvironments are associated with acid loading and cell metabolic processes generate acid equivalents.Cells have therefore evolved several mechanisms for proton extrusion, including plasmalemmal H+ATPase (active.when cells are acid loaded) and the Na/H+ antiporter (which in HPBMs is activated during formylmethionyl-leucyl phenylalanine induces acidosis.We have shown that inhibition of H+ATPase is associated with a mild intracellular acidosis (approx.00.2-0.3 pH unit below physiological pH) in HAMs and that this is associated with reduced Fc mediated phagocytosis.The aim of these experiments was to assess the role of H+ATPase in HPBM pH regulation and phagocytosis and assess its role in the generation of intracellular reactive oxygen species (a vital cytotoxic mechanism) in HAMs and HPBM.PH changes were monitored flow cytometrically using pH sensitive intracellular probes.Respiratory burst was assessed by the reduction of dihydrorhodamine.Fc mediated phagocytosis was assessed flow cytometrically following exposure to Fc opsonised FITC labelled E.Coli HPBMs failed to recover physiological pH following acid loading in the presence of a specific H+ATPase inhibitor bafilomycin A 1 (0.002 pH units/min(baf) vs 0.21 pH units/min, p<0.05), but recovery was insensitive to the antiporter inhibitor amiloride.Bafilomycin reduced Fc mediated phagocytosis (mean channel fluorescence (mcf) vs 465, p<0.005.Respiratory burst was reduced in HAMs (mcf 379 vs 480, p<0.05) and in HPBMs (224 vs 302, p<0.05).These results suggest a critical role for H+ATPases in regulation of cytosolic pH and effector function of these cells.

Crop ScienceVolume 36, Issue 3 cropsci1996.0011183X003600030046x p. 802-802 Registration of Cultivars Registration of ‘Sylvan’ Wheat J. S. Quick, Corresponding Author J. S. Quick [email protected] Dep. of Soil and Crop Sciences, Colorado State Univ., Fort Collins, CO, 80523Corresponding author ([email protected]).Search for more papers by this authorR. S. Albrechtsen, R. S. Albrechtsen Dep. of Plants, Soils, and Biometeorology, Utah State Univ., Logan, UT, 84322-4820Search for more papers by this authorM. Stack, M. Stack Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this author J. S. Quick, Corresponding Author J. S. Quick [email protected] Dep. of Soil and Crop Sciences, Colorado State Univ., Fort Collins, CO, 80523Corresponding author ([email protected]).Search for more papers by this authorR. S. Albrechtsen, R. S. Albrechtsen Dep. of Plants, Soils, and Biometeorology, Utah State Univ., Logan, UT, 84322-4820Search for more papers by this authorM. Stack, M. Stack Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this author First published: 01 May 1996 https://doi.org/10.2135/cropsci1996.0011183X003600030046xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. Volume36, Issue3May–June 1996Pages 802-802 RelatedInformation

Crop ScienceVolume 35, Issue 5 cropsci1995.0011183X003500050058x p. 1511-1512 Registration of Cultivars Registration of ‘Fisher’ Pinto Bean A. G. Fisher, A. G. Fisher Colorado State Univ., Fruita Res. Ctr., 1910 L Rd., Fruita, CO, 81521Search for more papers by this authorM. A. Brick, Corresponding Author M. A. Brick mbrick@ceres.agsci.colostate.edu Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Corresponding author (mbrick@ceres.agsci.colostate.edu).Search for more papers by this authorD. R. Wood, D. R. Wood Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this authorM. Stack, M. Stack Colorado State Univ., Fruita Res. Ctr., 1910 L Rd., Fruita, CO, 81521Search for more papers by this authorH. F. Schwartz, H. F. Schwartz Dep. of Plant Pathology and Weed Sci., Colorado State Univ., Fort Collins, CO, 80523Search for more papers by this authorJ. B. Ogg, J. B. Ogg Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this authorC. H. Pearson, C. H. Pearson Dep. of Soil and Crop SciencesSearch for more papers by this authorJ. F. Shanahan, J. F. Shanahan Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this authorM. Ballarin, M. Ballarin Plant Trademark and Copyright Office, 1320 Harbor Bay Parkway, Alameda, CA, 94501Search for more papers by this author A. G. Fisher, A. G. Fisher Colorado State Univ., Fruita Res. Ctr., 1910 L Rd., Fruita, CO, 81521Search for more papers by this authorM. A. Brick, Corresponding Author M. A. Brick mbrick@ceres.agsci.colostate.edu Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Corresponding author (mbrick@ceres.agsci.colostate.edu).Search for more papers by this authorD. R. Wood, D. R. Wood Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this authorM. Stack, M. Stack Colorado State Univ., Fruita Res. Ctr., 1910 L Rd., Fruita, CO, 81521Search for more papers by this authorH. F. Schwartz, H. F. Schwartz Dep. of Plant Pathology and Weed Sci., Colorado State Univ., Fort Collins, CO, 80523Search for more papers by this authorJ. B. Ogg, J. B. Ogg Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this authorC. H. Pearson, C. H. Pearson Dep. of Soil and Crop SciencesSearch for more papers by this authorJ. F. Shanahan, J. F. Shanahan Colorado State Univ., Southwestern Colorado Res. Ctr., Yellow Jacket, CO, 81335Search for more papers by this authorM. Ballarin, M. Ballarin Plant Trademark and Copyright Office, 1320 Harbor Bay Parkway, Alameda, CA, 94501Search for more papers by this author First published: 01 September 1995 https://doi.org/10.2135/cropsci1995.0011183X003500050058xCitations: 6AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article.Citing Literature Volume35, Issue5September–October 1995Pages 1511-1512 RelatedInformation