Preterm premature rupture of membranes (PPROM) occurs in approximately 2% of all pregnancies and responsible for one third of all preterm births. PPROM is an important cause of prematurity and the reported recurrence rate ranges from 14% to 21%1. PPROM is associated with both maternal and neonatal infection. Although the management of PPROM remains undefined antimicrobial treatment in expectant mamagement is common. We report one case of treatment of PPROM at 25 weeks’ gestation.

We aimed to evaluate short term results of the robotic-assisted and abdominal approach in patients performed hysterectomy with Burch colposuspension.

Abstract. Lichen sclerosus (LS) is a lymphocyte-mediated, chronic, inflammatory dermatitis which most commonly involves the anogenital area. Treatment options include topical corticosteroids, tacrolimus, carbon dioxide laser ablation and, as a last resort vulvectomy. The objective of this study is to report a refractory anogenital LS case and describe the use of a V-Y advancement flap for reconstruction of the perineal defect after vulvectomy. A case of persistent LS, treated succesfully with surgery is presented and the literature is reviewed. The patient tolerated the surgical procedure well and a satisfactory cosmetic result was obtained. A multidisciplinary team is ideal in the management of patients with persistent LS. Surgical management of LS should be reserved as a last resort for patients who are refractory to other medical treatment options and, in the case of a surgical attempt, techniques for reconstruction of the vulva should be well known. Key words: Lichen sclerosus, vulvectomy, vulvar reconstruction

Female genital tuberculosis is a cause of pelvic inflammatory disease and infertility. Pelvic tuberculosis usually occurs secondary to the pulmonary tuberculosis. We report a 38-year-old patient with renal transplantation. Tuberculosis endometritis was diagnosed after endometrial sampling due to irregular uterine bleeding.

A rare case of a patient with a histopathological diagnosis of a sarcomatous-type peritoneal malign mixed müllerian tumor implant in association with ovarian adenocarcinoma is reported. A 52-year-old patient was referred to our clinic for an adnexal mass. At pelvic examination, an irregular, fixed, approximately 7-8 cm in size mass was detected in the right adnexal area. At transvaginal ultrasonographic examination, it was observed that there was an 80 x 70 mm sized, irregularly contoured, semisolid mass with hyperechogenous areas inside originating from the ovary in the right adnexal area. At laboratory examination tumor marker CA-125 was 280.4 U/ml (< 35), CA-15-3 was 146.5 U/ml (< 25), whereas other markers were within normal range. The patient was operated on for a right adnexal mass. A staging laparatomy procedure was applied. Postoperative histopathological diagnosis was reported as malignant mixed mullerian tumor of the ovary, with the ovarian component as poorly differentiated adenocarcinoma, and the metastatic foci over serosal surfaces as a sarcomatous component. Postoperatively six courses of adjuvant and consolidation chemotherapy were administered to the patient. Further studies are needed to set a consensus about evaluation of treatment and prognosis for this kind of pathology.

As is known, tamoxifen therapy is related to endometrial proliferation, hyperplasia, polyp formation, invasive carcinoma and uterine sarcoma. In this study, we present a 75-year-old woman who had five children. Gastric tumor, endometrial carcinoma and cervical adenocarcinoma in situ were detected after treatment with tamoxifen for breast cancer. It seems that being aware of the undesirable affects of tamoxifen treatment during the chemotherapy and post-chemotherapy period is very important.

Female genital tuberculosis is a cause of pelvic inflammatory disease and infertility. Pelvic tuberculosis usually occurs secondary to the pulmonary tuberculosis. We report a 38-year-old patient with renal transplantation. Tuberculosis endometritis was diagnosed after endometrial sampling due to irregular uterine bleeding.

OBJECTIVE: To compare the two surgical techniques (laparoscopy vs laparotomy), postoperative complications, duration of hospitalization and patient profiles in the management of mature cystic teratoma of ovary. DESIGN-METHOD: One hundred and thirty one patients with ovarian mature cystic teratoma, who were surgically treated during 1994-2003, were retrospectively analysed. Laparoscopy was done for 71 patients, and 60 patients were operated via laparotomy. The two groups were compared for the aspects of demografic properties, symptomatology, operative technique, postoperative complications and duration of hospitalization. RESULTS: There was no statistically significant difference for the aspects of patient age, the size of the cyst, and bilaterality. Laparoscopy was done in a mean duration of 69±4.1 minutes, and laparotomy was completed in 52±2.8 minutes. Duration of hospitalization was 1.6±0.8 days after laparoscopy and 3.1±0.2 days after laparotomy (p

Objective: To evaluate survival and peri-operative morbidity in patients with Stage III and Stage IV endometrial carcinoma undergoing optimal versus suboptimal cytoreductive surgery. Methods: All patients with FIGO Stage III and Stage IV endometrial carcinoma who underwent surgical therapy at Jackson Memorial Hospital between 01/01/90 — 12/31/2001 were identified. Patient data were gathered retrospectively. Survival analysis and comparisons were performed using the Kaplan-Meier method, the log-rank test, and Chi-square analysis. Results: Eighty-four patients were identified; 60 patients with Stage III and 24 patients with Stage IV disease. Optimal cytoreduction was accomplished in 83 percent of patients (n1⁄4 70) while 17 percent (n1⁄4 14) had suboptimal cytoreduction (greater than 1cm residual tumor). A significant survival advantage was associated with optimal cytoreduction (p1⁄4 0.039). When stratified by stage, Stage III patients with optimal cytoreduction demonstrated significant survival advantage over Stage III patients with suboptimal cytoreduction (p1⁄4 0.034). Optimal cytoreduction did not increasemajor andminor intra-operative or post-operative morbidity. SICU admissions and death less than 30 days from surgery were associated with suboptimal cytoreductive surgery (p1⁄4 0.0120, p1⁄4 0.0037 respectively). Tumor involvement of the parametrium, adnexae, upper abdomen, and the presence of ascites at timeof surgerywere independent predictors of suboptimal resectability. Conclusion: Optimal cytoreduction in patients with Stage III and Stage IV endometrial cancer is not associated with an increase in peri-operative morbidity. Suboptimal cytoreduction is associated with increased morbidity and decreased survival.