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1β-Adrenergic 1-[1-benzimidazolyl]-N-[2-(4-hydroxy-3-methoxy-phenyl)-2-hydroxy-ethyl]- 3-amino butane and salts and hydrates thereof

Michel Joannic, Francoise Roquet,Marcel Pesson

1985引用：26

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2(Benzimidazolyl-1)-1,N-((hydroxy-4 méthoxy-3 phényl)-2 hydroxy-2 éthyl) amino-3 butane et ses sels et hydrates à activité bêta-adrénergique, leurs applications thérapeutiques, et procédé pour les préparer

Michel Joannic, Francoise Roquet,Marcel Pesson

1983引用：23

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31-Aryl-4-γ-arylsulphonyl-3-aminopropoxy-1H-pyrazoles and their use as hypolipemiant and hypocholesterolemiant agents

Henri Techer, Gilles Monnier,Marcel Pesson

1982引用：29

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4[A New Synthetic Antibacterial : 1-Ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1, 4-Dihydroquinolin-3-carboxylic Acid (1589 R.B.)].

Y GOUEFFON,G MONTAY,F ROQUET,M PESSON

The 1,4-dihydro-1-ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxoquinoline- 3-carboxylic acid (1589 R.B.) is a broad antibacterial agent active in experimental infections. The toxicological and pharmacokinetic profiles of the compound administered as methane sulfonic salt (1589 m R.B.), seem to suggest the possibility of using it in systemic infections.

1981COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES（1981）引用：24

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5SYNTHETIC ANTI-BACTERIAL AGENTS - PYRIDO (2,3-E) ASYM TRIAZINE-7 CARBOXYLIC-ACIDS DERIVATIVES

M PESSON,M ANTOINE,JL BENICHON,P DELAJUDIE,E HORVATH,B LERICHE,S PATTE

1980EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（1980）

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6ChemInform Abstract: SYNTHETIC ANTIBACTERIAL AGENTS. PYRIDO(2,3‐E)‐AS‐TRIAZINE‐7‐CARBOXYLIC ACID DERIVATIVES

M. PESSON,M. ANTOINE,J.‐L. BENICHON,P. DE LAJUDIE,E. HORVATH,B. LERICHE,S. PATTE

AbstractDie aus dem Methyhnercaptotriazin (I) und den Aminoessigestern (II) dargestellten Derivate (III) cyclisieren in alkalischem Medium zu den Hydroxydihydropyridotriazinen (IV), die durch Bromierung und anschließende Dehydrobromierung oder durch Dehydrierung mit Chloranil in die Oxo‐Derivate (V) übergeführt werden.

1980Chemischer Informationsdienst

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7ChemInform Abstract: SYNTHETIC ANTIBACTERIAL AGENTS. PIPEMIDIC ACID DERIVATIVES

M. PESSON,M. ANTOINE,P. GIRARD,J.‐L. BENICHON,S. CHABASSIER,P. DE LAJUDIE,S. PATTE,F. ROQUET,G. MONTAY

AbstractZur Untersuchung der Beziehung zwischen antibakterieller Wirkung und Struktur werden zahlreiche am Piperazin‐Ring N‐substituierte Derivate der pharmakologisch bekannten Pipemidsäure synthetisiert.

1980Chemischer Informationsdienst

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8Synthetic Anti-Bacterial Agents - Pipemidic Acid-Derivatives

M PESSON,M ANTOINE,P GIRARD,JL BENICHON,S CHABASSIER,P DELAJUDIE,S PATTE,F ROQUET,G MONTAY

1980EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（1980）

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9ChemInform Abstract: 4‐ALKYL‐1,4‐4H‐BENZOTHIAZINE‐2‐CARBOXYLIC ACID 1,1‐DIOXIDES

HENRI TECHER,MARC LAVERGNE,MARCEL PESSON

AbstractDie durch Kondensation der Na‐Sulfinate (I) mit dem Halogenester (II) zugänglichen Sulfonylacetate (III) reagieren mit dem Aminoacetal (IV) zu den Acrylaten (V), deren Nitrogruppe an Raney‐ Ni hydriert wird unter Bildung der Derivate (VI).

1976Chemischer Informationsdienst

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10NEW KIND OF GLUCOSE ESTERS CONTAINED IN SENECIO SPECIES

P FORGACS,J PROVOST,JF DESCONCLOIS,A JEHANNO,R TIBERGHIEN,A TOUCHE,F ROQUET,F GODARD,M PESSON

1976COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE D

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11ChemInform Abstract: 1‐ALKYL‐4‐OXO‐1,4‐DIHYDROPYRIDO(2,3‐B)QUINOXALINE‐3‐CARBOXYLIC ACIDS WITH ANTIBACTERIAL ACTION

MARCEL PESSON,PIERRE DE LAJUDIE,MICHEL ANTOINE,SIMONE CHABASSIER,PHILIPPE GIRARD

AbstractDurch Cyclisieren der aus den entsprechenden 2‐Chlor‐chinoxalinen und N‐Methyl‐ oder N‐Äthyl‐β‐alanin (anschließende Veresterung) erhältlichen Diester (I) wurden die Ester (II) dargestellt, die sich durch Bromieren, Dehydrobromieren und Verseifen in die Titelverbindungen (III) überführen lassen.

1976Chemischer Informationsdienst

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121-ALKYL 4-OXO 1,4-DIHYDRO PYRIDO[2,3-B]QUINOXALINE-3 CARBOXYLIC-ACIDS WITH ANTIBACTERIAL EFFECTS

M PESSON,P DELAJUDIE,M ANTOINE,S CHABASSIER,P GIRARD

1976COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C

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13ChemInform Abstract: ANTIBACTERIALS. 8‐ALKYL‐5,8‐DIHYDRO‐5‐OXO‐6‐PYRIDO(2,3‐D)PYRIMIDINECARBOXYLIC ACIDS DERIVATIVES. III. 2‐(4‐ARYLPIPERAZINYL)‐, 2‐(4‐ARALKYLPIPERAZINYL)‐, AND 2‐(2‐IMIDAZOLINYL)‐ DERIVATIVES

M. MARCEL PESSON,MICHEL ANTOINE,PHILIPPE GIRARD,SIMONE CHABASSIER, DENISE RICHTER,JEAN‐LOUIS BENICHON,M. PIERRE DE LAJUDIE,ELISABETH HORVATH, BERNADETTE LERICHE,SIMONE PATTE

Chemischer InformationsdienstVolume 7, Issue 16 Heterocyclic Compounds ChemInform Abstract: ANTIBACTERIALS. 8-ALKYL-5,8-DIHYDRO-5-OXO-6-PYRIDO(2,3-D)PYRIMIDINECARBOXYLIC ACIDS DERIVATIVES. III. 2-(4-ARYLPIPERAZINYL)-, 2-(4-ARALKYLPIPERAZINYL)-, AND 2-(2-IMIDAZOLINYL)- DERIVATIVES M. MARCEL PESSON, M. MARCEL PESSONSearch for more papers by this authorMICHEL ANTOINE, MICHEL ANTOINESearch for more papers by this authorPHILIPPE GIRARD, PHILIPPE GIRARDSearch for more papers by this authorSIMONE CHABASSIER, SIMONE CHABASSIERSearch for more papers by this authorDENISE RICHTER, DENISE RICHTERSearch for more papers by this authorJEAN-LOUIS BENICHON, JEAN-LOUIS BENICHONSearch for more papers by this authorM. PIERRE DE LAJUDIE, M. PIERRE DE LAJUDIESearch for more papers by this authorELISABETH HORVATH, ELISABETH HORVATHSearch for more papers by this authorBERNADETTE LERICHE, BERNADETTE LERICHESearch for more papers by this authorSIMONE PATTE, SIMONE PATTESearch for more papers by this author M. MARCEL PESSON, M. MARCEL PESSONSearch for more papers by this authorMICHEL ANTOINE, MICHEL ANTOINESearch for more papers by this authorPHILIPPE GIRARD, PHILIPPE GIRARDSearch for more papers by this authorSIMONE CHABASSIER, SIMONE CHABASSIERSearch for more papers by this authorDENISE RICHTER, DENISE RICHTERSearch for more papers by this authorJEAN-LOUIS BENICHON, JEAN-LOUIS BENICHONSearch for more papers by this authorM. PIERRE DE LAJUDIE, M. PIERRE DE LAJUDIESearch for more papers by this authorELISABETH HORVATH, ELISABETH HORVATHSearch for more papers by this authorBERNADETTE LERICHE, BERNADETTE LERICHESearch for more papers by this authorSIMONE PATTE, SIMONE PATTESearch for more papers by this author First published: April 20, 1976 https://doi.org/10.1002/chin.197616230AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume7, Issue16April 20, 1976 RelatedInformation

1976

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144-ALKYL 1.4-4 H-BENZOTHIAZINE 1.1-DIOXYDE 2-CARBOXYLIC ACIDS - NOTICE

M LAVERGNE,M PESSON

1976COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C

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15ChemInform Abstract: 8‐ALKYL‐5‐OXO‐5,8‐DIHYDRO‐PYRIDO(2,3‐D)PYRIMIDIN‐6‐CARBONSAEURE‐DERIVATE MIT ANTIBAKTERIELLER WIRKUNG 1. MITT. NEUE DARSTELLUNGS‐VERFAHREN

M. PESSON,M. ANTOINE,S. CHABASSIER,S. GEIGER,P. GIRARD,D. RICHER,P. DE LAJUDIE,E. HORVATH,B. LERICHE,S. PATTE

AbstractDie Kondensation der Pyrimidine (I) mit dem Propionat (II) liefert die Tetrahydroderivate (III) (Ringbildung erfolgt nach Dieckmann).

1975Chemischer Informationsdienst

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16ANTIBACTERIALS - 8-ALKYL 5,8-DIHYDRO-5-OXO-6-PYRIDO[2,3-D]PYRIMIDINE CARBOXYLIC-ACIDS DERIVATIVES .3. 2-(4-ARYLPIPERAZINYL), 2-(4-ARALKYLPIPERAZINYL) AND 2-(DELTA-2 IMIDAZOLINYL) DERIVATIVES

M PESSON,M ANTOINE,P GIRARD,S CHABASSIER,D RICHER,JL BENICHON,P DELAJUDIE,E HORVATH,B LERICHE,S PATTE

1975EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（1975）

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17ChemInform Abstract: NITRILE UND AMID‐OXIME VON 8‐ALKYL‐5‐OXO‐5,8‐DIHYDRO‐PYRIDO(2,3‐D)PYRIMIDIN‐6‐CARBONSAEUREN

MARCEL PESSON,SIMONE CHABASSIER

AbstractDas nach bekannter Methode aus dem Pyrimidin (I) über den Nitrilester (II) dargestellte Tetrahydropyridopyrimidin (III) liefert nach Bromierung und anschließender Dehydrobromierung das Dihydroderivat (IV).

1975

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18SYNTHESIS OF 1-ALKYL-4-OXO-1,4-DIHYDRO BENZO [H]-1,6-NAPHTYRIDINE 3-CARBOXYLIC ACIDS WITH ANTIBACTERIAL ACTION

M PESSON,P DELAJUDIE,M ANTOINE,P GIRARD,S CHABASSIER

1975COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C

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19ChemInform Abstract: 8‐ALKYL‐5‐OXO‐5,8‐DIHYDRO‐PYRIDO(2,3‐D)PYRIMIDIN‐6‐CARBONSAEURE‐DERIVATE MIT ANTIBAKTERIELLER WIRKUNG 2. MITT. 2‐PIPERAZINYL‐ UND 2‐(4‐ALKYL‐PIPERAZINYL)‐DERIVATE

M. PESSON,M. ANTOINE,S. CHABASSIER,S. GEIGER,P. GIRARD,D. RICHER,P. DE LAJUDIE,E. HORVATH,B. LERICHE,S. PATTE

AbstractDie Piperazinyl‐Derivate (IIIa) werden durch Kondensation der Piperazine (Ia) mit dem Chlorpyridopyrimidin (II) erhalten, die zu den Säuren (IIIb) verseift werden.

1975Chemischer Informationsdienst

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20ChemInform Abstract: DARSTELLUNG VON 1‐ALKYL‐4‐OXO‐1,4‐DIHYDRO‐BENZO(H)(1,6)NAPHTHYRIDIN‐6‐CARBONSAEUREN MIT ANTIBAKTERIELLER WIRKUNG

MARCEL PESSON,PIERRE DE LAJUDIE,MICHEL ANTOINE,PHILIPPE GIRARD,SIMONE CHABASSIER

AbstractDie Kondensationsprodukte (III) der Chinoline (I) mit der Aminosäure (II) werden mit Äthanol verestert und mit K‐tert.‐butanolat zu den Tetrahydronaphthyridinen (IV) cyclisiert.

1975Chemischer Informationsdienst

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