The objective of this study was to report clinical, epidemiological, and anatomopathological data in cattle affected by colitis and perforating ulcerative typhlitis with peritonitis; three (n=3) bovines affected by colitis and two (n=2) with ulcerative typhlocolitis. Clinically, apathy stood out, accompanied by difficulty in exploring the abdominal organs through rectal palpation because of low mobility of the organs due to adhesions. The animals died, and, on necroscopic examination, diffuse, fibrinous purulent peritonitis was recorded due to perforating, multifocal ulcerated areas in the colon and cecum wall. Histopathological examination recorded data compatible with acute, necrotizing, and perforating ulcerative enteritis, with thrombus in the blood vessels associated with fibrinoid necrotizing vasculitis. The immunohistochemistry test for Salmonella spp. was positive in four of the five samples analyzed. The etiopathogenesis of perforating ulcerative typhlocolitis in cattle is associated with infection by Salmonella spp., while not ruling out the possibility of participation of other etiologic agents in the occurrence of this disease, due to the complexity of the disease and the scarcity of reports in the literature, further investigations are necessary to provide a better understanding of this disease in cattle.

Resumo Os estudos relacionados as doenças neurológicas assumem grande importância na Medicina Veterinária, particularmente os que envolvem animais de produção como os bovinos, em virtude da grande importância sanitária e de saúde pública. Nesse contexto, este trabalho teve como objetivo descrever a frequência de ocorrência dos principais achados clínicos, laboratoriais e anatomopatológicos dos bovinos diagnosticados com doenças neurológicas de origem viral. Realizou-se a triagem no livro de registro geral dos pacientes com enfermidades que cursaram com sintomatologia neurológica e que foram diagnosticados através de exame anatomopatológico e/ou complementares com enfermidades de origem viral, os quais deram entrada (vivos ou mortos) na Clínica de Bovinos de Garanhuns-UFRPE no período de janeiro de 2009 a dezembro de 2019. As informações obtidas foram inseridas em um banco de dados elaborado no programa de computador Microsoft Excel 2010® distribuídas em dados clínicos, laboratoriais e anatomopatológicos. Os achados clínicos das enfermidades neurológicas de etiologia viral foram muito variados e inespecíficos, sendo os achados anatomopatológicos, aliados aos métodos laboratoriais, de importância fundamental para o estabelecimento do diagnóstico. A elevada frequência dos casos de raiva neste estudo demonstra a importância sanitária desta enfermidade para a pecuária bovina, como também para a saúde pública. Ressalta-se a importância da inclusão da febre catarral maligna e da meningoencefalite herpética no diagnóstico diferencial das doenças neurológicas na região, assim como a adoção de medidas sanitárias.

Abstract Studies related to neurological diseases are of great importance in Veterinary Medicine, particularly those involving production animals, such as cattle, due to their wide sanitary and public health significance. Therefore, the current study aims to describe the frequency of occurrence of the main clinical, laboratory, and anatomopathological findings of cattle diagnosed with neurological diseases of viral origin. Screening was performed in the general register of patients diagnosed through anatomopathological and/or complementary examination with illnesses of viral origin, admitted (live or dead) to the Clínica de Bovinos de Garanhuns-UFRPE from January 2009 to December 2019. The information recovered was entered in a database created in the computer program Microsoft Excel 2010®, distributed into clinical, laboratory, and anatomopathological data. The clinical findings on neurological diseases of viral etiology were very varied and non-specific, and the anatomopathological findings, together with laboratory methods, were of fundamental importance for the establishment of the diagnosis. The high frequency of rabies cases in this study demonstrates the importance of this disease for cattle rearing, as well as for Public Health. We emphasize the importance of including malignant catarrhal fever and herpes meningoencephalitis in the differential diagnosis of neurological diseases in the region, as well as the adoption of sanitary measures.

Abstract Neurological disorders in cattle comprise a group of economically relevant diseases with high occurrence and mortality. In this way, the objective was to carry out an epidemiological study of the diseases with neurological manifestations in cattle admitted (alive or dead) to the Garanhuns Bovine Clinic/Federal Rural University of Pernambuco (CBG/UFRPE) from January 2009 to December 2019. Epidemiological information was collected from the clinical records regarding the age group, rearing system, time of year, and area of origin of the animals. The diseases were grouped into categories according to their origin: toxic or toxi-infectious, viral, traumatic/physical, parasitic, metabolic degenerative, bacterial, neoplastic, and others. A total of 6103 cattle were treated during the study period, of which 604 (10.1%) were diagnosed with diseases that had neurological manifestations. Of these, 331 cases were of single occurrence, and 231 cases occurred as outbreaks in the herd. Death was the outcome in almost 80% of the cases (465/596). The frequencies of the different categories were toxic or toxi-infectious (25.2%), viral (21.5%), traumatic/physical (13.6%), parasitic (9.8%), metabolic (9.3%), degenerative (2.3%), bacterial (2.2%), neoplastic (1.2%), and others (1.2%). It was found that almost half of the animals were older than 24 months (229/475), almost 80% were females, more than 60% were submitted to a semi-intensive to intensive rearing system, and the occurrence of disease was higher during the dry period of the year (363/614). The three most frequent neurological diseases in this study were rabies, trauma, and botulism.

Resumo Os distúrbios neurológicos em bovinos abrangem um grupo de enfermidades economicamente relevantes de elevada ocorrência e mortalidade. Desta forma, objetivou-se realizar um estudo epidemiológico das enfermidades que cursaram com manifestações neurológicas que deram entrada (vivos ou mortos) na Clínica de Bovinos de Garanhuns/Universidade Federal Rural de Pernambuco no período de janeiro de 2009 a dezembro de 2019. Nos prontuários clínicos, foram coletadas informaçõe epidemiológicas referentes ao sexo; a faixa etária; ao sistema de criação, época do ano e a área de procedência dos animais. As doenças foram agrupadas em categorias de acordo com sua origem: tóxica ou toxi-infecciosa, viral, traumática, parasitária, degenerativa, metabólica, bacteriana, neoplásica e outras. Um total de 6103 bovinos foram atendidos no período estudado, dos quais 604 (10,1 %) foram diagnosticados com enfermidades que cursaram com manifestações neurológicas. Destes, 331 casos foram de ocorrência individual, 231 casos cursaram como surtos no rebanho. Quase 80% dos casos (465/596) teve o óbito como desfecho. As frequências das distintas categoria foram tóxica ou toxi-infecciosa (25,2%), viral (21,5%), traumática/física (13,6%), parasitária (9,8%), metabólica (9,3%, degenerativa (2,3%), bacteriana (2,2%), neoplásica (1,2%), outras (1,2%). Verificou-se que quase metade dos animais apresentavam idade superior a 24 meses (229/475), quase 80% eram fêmeas, mais de 60% eram submetidos a um sistema de criação de semi-intensivo a intensivo e a ocorrência foi maior durante o período seco do ano (363/614). As três enfermidades com manifestações neurológicas de maior ocorrência neste estudo foram a raiva, os traumatismos e o botulismo.

In humans, C. burnetii infection is known as Q fever, in animals the term coxiellosis is considered more appropriate than animal Q fever. This is a worldwide distribution zoonosis caused by a gram-negative obligate intracellular bacterium of the order Legionellales, which has been classified as a potential bioterrorism agent. Cattle and small ruminants represent the most frequent sources of infection in humans, with inhalation of contaminated aerosols from infected animal products being the main form of transmission. The present study aims to perform a literature review on coxiellosis, evidence of C. burnetii circulating in animals and humans in Brazil and its close relationship to public health, due to its zoonotic nature, in addition to its economic importance for national livestock.

We describe here hematological and biochemical findings in a cow with metastatic cholangiocarcinoma. On physical examination, apathy with congested mucous membranes, tachycardia and enlarged abdomen; hypoperistalsis in rumen, abomasum and intestines. In hematological examination, icteric plasma with leukocytosis by neutrophilia with regenerative left shift and inversion of the proportion between lymphocytes and segmented neutrophils, and hypofibrinemia. In serum biochemistry: hyperproteinemia, hypoalbuminemia, hyperglobulinemia, low albumin/globulin ratio and high levels of aspartate aminotransferase, gamma-glutamyltransferase. The cow died and in necropsy was observed a severe and diffuse increase in volume predominantly on the hepatic right lobe and moderate increase of volume in mesenteric lymph nodes. Which was diagnosed microscopically as a cholangiocarcinoma, characterized by arrangements in irregular and coalescent ducts. In conclusion, cholangiocarcinoma may cause important hematological and biochemical changes in cattle.

The carpal joint in goats is subject to diseases such as caprine arthritis encephalitis, leading to pain and a reduction in movement. Due to the scarce records of normal parameters, the aim of the present study was to assess the physiochemical and cytological make up of the synovial fluid in the carpal joint of 44 mixed-breed goat without joint disease. The following physiochemical characteristics were assessed: volume (0.94mL ± 0.26 mL), color (colorless to yellow), turbidity (46.50% were limpid), mucin precipitation (firm coagulant in limpid solution) and concentration of total proteins (1.95 ± 0.87 mg/dL). Cytological assessment consisted of global and differential leukocyte counts. The mean global count was 48.02 ± 24.47 cells/μL. The differential count was 25.07 ± 15.86 lymphocytes/μL and 16.31 ± 12.63 large mononucleated cells/μL. It is suggested that the parameter values obtained in the present study may be considered normal for synovial fluid in the carpal joint of adult mixed-breed goats.

The carpal joint in goats is subject to diseases such as caprine arthritis encephalitis, leading to pain and a reduction in movement. Due to the scarce records of normal parameters, the aim of the present study was to assess the physiochemical and cytological make up of the synovial fluid in the carpal joint of 44 mixed-breed goat without joint disease. The following physiochemical characteristics were assessed: volume (0.94mL ± 0.26 mL), color (colorless to yellow), turbidity (46.50% were limpid), mucin precipitation (firm coagulant in limpid solution) and concentration of total proteins (1.95 ± 0.87 mg/dL). Cytological assessment consisted of global and differential leukocyte counts. The mean global count was 48.02 ± 24.47 cells/µL. The differential count was 25.07 ± 15.86 lymphocytes/µL and 16.31 ± 12.63 large mononucleated cells/µL. It is suggested that the parameter values obtained in the present study may be considered normal for synovial fluid in the carpal joint of adult mixed-breed goats.KEY WORDS: Carpus, goat, joint, synovia.A articulação do carpo dos caprinos é alvo de enfermidades, como a artrite-encefalite caprina, levando à dor e à redução dos movimentos. Devido à falta de registro de parâmetros normais, este estudo avaliou a constituição físico-química e citológica do líquido sinovial da articulação do carpo de 44 caprinos sem raça definida, que não apresentavam doença articular. Os parâmetros físico-químicos avaliados foram volume (0,94 mL ± 0,26 mL), cor (incolor a amarelo), turbidez (46,50% apresentaram-se límpidas), precipitado de mucina (coágulo firme em solução límpida) e concentração de proteínas (1,95 ± 0,87 mg/dL). Os dados citológicos corresponderam às contagens global e diferencial de leucócitos. A contagem global média encontrada foi de 48,02 ± 24,47 células/µL e contagem diferencial com 25,07 ± 15,86 linfócitos/µL e 16,31 ± 12,63 grandes células mononucleadas/µL. Sugere-se que os valores obtidos nesta pesquisa sejam considerados parâmetros normais para o líquido sinovial do carpo de caprinos adultos sem raça definida.PALAVRAS-CHAVES: Articulação, caprino, carpo, sinóvia.

A articulação do carpo dos caprinos é alvo de enfermidades, como a artrite-encefalite caprina, levando à dor e à redução dos movimentos. Devido à falta de registro de parâmetros normais, este estudo avaliou a constituição físico-química e citológica do líquido sinovial da articulação do carpo de 44 caprinos sem raça definida, que não apresentavam doença articular. Os parâmetros físico-químicos avaliados foram volume (0,94 mL ± 0,26 mL), cor (incolor a amarelo), turbidez (46,50% apresentaram-se límpidas), precipitado de mucina (coágulo firme em solução límpida) e concentração de proteínas (1,95 ± 0,87 mg/dL). Os dados citológicos corresponderam às contagens global e diferencial de leucócitos. A contagem global média encontrada foi de 48,02 ± 24,47 células/µL e contagem diferencial com 25,07 ± 15,86 linfócitos/µL e 16,31 ± 12,63 grandes células mononucleadas/µL. Sugere-se que os valores obtidos nesta pesquisa sejam considerados parâmetros normais para o líquido sinovial do carpo de caprinos adultos sem raça definida. PALAVRAS-CHAVES: Articulação, caprino, carpo, sinóvia.

This study was conducted in order to describe the clinical and laboratorial findings of gastrointestinal obstruction by phytobezoar in cattle. Twenty-five cases were analyzed which the animals received diets composed mainly by cactus forage (Opuntia sp), and scarce and low quality roughage. The disease showed acute and subacute evolutions, with state of apathy, dehydration, tachycardia, anorexia, colic, rumen and intestine hypomotility, with the last one being fulfilled with liquid. The feces were rare, there was just mucus in some and phytobezoar palpation was possible in intestinal segments of some animals. Ruminal fluid characteristics were altered. The hematology revealed hyperfibrinogenemia and leukocytosis by neutrophilia.Este trabalho teve por objetivo descrever os achados clínicos e laboratoriais da obstrução gastrointestinal por fitobezoários em bovinos. Analisaram-se 25 casos, observando-se que a maioria dos animais recebia dieta composta principalmente por palma forrageira (Opuntia sp), o fornecimento de volumoso era escasso e com baixa qualidade. A doença teve evolução aguda a subaguda, com os animais apresentando apatia, desidratação, taquicardia, anorexia, cólicas, hipomotilidade ruminal e de intestino, que se apresentava repleto de líquido. Na maioria dos animais as fezes eram escassas, em alguns deles havia apenas muco e foi possível a palpação dos fitobezoários em segmentos intestinais. Houve alteração das características do fluido ruminal. No hemograma constatou-se um quadro de leucocitose por neutrofilia e hiperfibrinogenia.