A general method for the synthesis of amino acid and peptide derivatives of fullerene (ADF) was developed, and the physicochemical properties of the compounds obtained were studied. ADF were shown to penetrate into liposomes and to exhibit adjuvant properties and antiviral activity.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Aprotic organic superacids CX4 ·nAlBr3 (X = Br, CI; n = 1 or 2) are effective initiators of carbonylation of propane with CO in an organic solvent at -10 to -20 °C.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Aprotic organic superacids CBr4 · 2AlBr3, CBr4 · AIBr3, CHBr3 · 2AlBr3, CCl4 · 2AlBr3, and C6F5CF3 -2AlBr3 efficiently catalyze the bromination of alkanes and cycloalkanes with Br2. Ethane is selectively brominated at 55–65 °C to give mostly 1,2-dibromoethane (stoichiometric reaction). Propane, butane, cyclopentane, cyclohexane, and methylcyclopentane react with Br2 at -40 to -20 °C with good selectivity affording monobromides in high yields (catalytic reactions).

Structures of micelles ofN-(monohydrofullerenyl)-l-alanine and their associates were studied by tunneling scanning microscopy in the regime of a profilometer with a 10-nm resolution along the vertical line. The data obtained show that the micelles of the compound studied are anisodiametric particles 0.5–10 μm in size containing negligible amounts of water. The thickness of the micelles depends on their lengths.

Fragments of the potential energy surfaces (PES) for the SOCl2 . nAlCl(3) (n = 1, 2) complexes were calculated by the ab initio MO LCAO method using the RHF approximation for the STO-3G basis set adding a 3d-AO for the S atom, as well as the semiempirical MNDO method. Two local minima, assigned to the donor-acceptor complex Cl2SO-->AlCl3 (1a) and to Cl3SOAlCl2 (1b) were located on the PES at n = 1. Two local minima corresponding to two donor-acceptor complexes Cl2SO-->Al2Cl(6) and[GRAPHICS]were also located on the PES at n = 2. An analysis of the enthalpies of cation formation in the SOCl2 + nAlCl(3) (n = 1-3) systems calculated by the ab initio method shows that the enthalpy of formation of the SOCl+ cation at n = 2 is 17 kcal mol(-1) less than that at n = 1; the structure of the Cl2SOAlCl2+ cation with two strong electrophilic centers at the Al and S atoms becomes more favorable energetically at n = 3. The results of calculations for Cl2SO.nAlCl(3) complexes by the MNDO method are in agreement with those obtained by the ab initio method except for the geometry of complexes containing the Cl3SO fragment and the charge values on the S atoms.

Geometric, electronic, and energy characteristics of the complexes formed in the CF4 ·nAIF3 (n = I or 2) and CBr4 ·nAIBr3 (n = 1, 2, or 4) systems have been determined by the semiempirical AM I method. Besides the donor-acceptor complexes, the CBr3+...AIBr4−, CBr3+...Al2Br7−, CBr22+...(AlBr4−)2, and CBr22+...(Al2Br7−)2 ionic complexes can be formed in the CBr4 ·nAlBr3 systems. In the cations and dications of polyhalomethanes (when Hal = Cl, Br, or l) in both the free and bound (included in ionic complexes) states, carbon atoms carry negative charges, the C-Hal bonds are substantially shortened, and the positive charges are located on one-coordinate halogen atoms. These cations and dications can be considered as halenium ions that differ from halenium salts with dicoordinate halogen atoms. In the cationic and dicationic complexes of the CBr4 ·nAlBr3 systems, the maximum positive charges on the Br atoms are 0.39 and 0.94, respectively. Fluorine-containing cations and dications have structures similar to those of carbenium ions, whereas in the CF4 ·nAIF3 systems (n = l or 2), only donor-acceptor complexes are formed.

Co- and Fe-phthalocyanine complexes with cationic and anionic substituents in the macroligand, which are effective in autooxidation of ascorbic acid in aqueous solutions, are studied in the reaction of oxidative cleavage of nucleic acids. It was shown for the first time that water-soluble, metal-phthalocyanine complexes can cleave nucleic acids in the reaction of dark conjugated autooxidation of ascorbic acid. Fe-octakis(pyridinio-methyl)phthalocyanine chloride is the most efficient in oxidative degradation of RNA target, and Co- and Fe-phthalocyanine cationic complexes are the most efficient in oxidative degradation of DNAs. Using the radical traps, it was shown that the oxidative degradation of nucleic acids is caused by OH-radicals.

New acetylene complexes of titanocene and permethyltitanocene Cp2Ti(R1C2R2) and Cp2*Ti(R1C2R2) (R1R2SiMe3; R1Ph, R2SiMe3) without additional ligands have been prepared by the reaction of Cp2TiCl2 and Cp2*TiCl2 with equimolar amounts of Mg and the appropriate acetylene R1C2R2 in THF. The complexes have been isolated from the reaction mixture in an analytically pure state and characterized by spectral methods. The structures of complexes Cp2Ti(PhC2SiMe3), Cp2*Ti(PhC2SiMe3) and Cp2*Ti(Me3SiC2SiMe3) have been proved by an X-ray diffraction study. Some chemical properties of the synthesized complexes have been investigated.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

The study of complex formation between adenosine triphosphate (ATP) or adenosine diphosphate (ADP) and coordinationally unsaturated cobalt complex with 2, 9-dimethyl-o-phenanthroline (L) showed the possibility of formation of relatively stable mixed ligand complex CoL·ATP (logβ=4.45). The latter may be formed under the oxidative phosphorylation conditions in mitochondria. The presence of ATP in the complex provides the specific inhibition of the ATPase active center.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.