BACKGROUND:Understanding whether living alone correlates with depression and suicidal ideation is key to identifying older adults at risk. METHODS:We pooled data from the 2005, 2010, 2017, and 2021 nationally representative cross-sectional Health Barometer surveys conducted by Santé Publique France, and focused on adults aged 65 to 75 (n = 12,026). Logistic regressions were performed to identify associations between 12-month major depressive episode (MDE), suicidal ideation (SI) and living alone, adjusting for sociodemographic factors. Analyses were conducted in the overall sample and stratified by sex. RESULTS:Overall, 18.3% of men and 33.8% of women lived alone. In total, 5.5% of adults experienced MDE: 8.8% of those living alone and 4.3% of those not living alone (χ2 = 80.94, df = 1, p < .001), and 2.9% reported SI: 4.8% of those living alone and 2.1% of those not living alone (χ2 = 55.60, df = 1, p < .001). In the overall sample and controlling for sociodemographic factors, living alone was associated with MDE (AOR = 1.80, 95%CI = 1.51-2.14). This held true both among men (AOR = 2.30, 95%CI = 1.60-3.32) and among women (AOR = 1.69, 95%CI = 1.38-2.06). Controlling for sociodemographic factors and MDE, living alone was associated with 12-month SI (AOR = 1.90, 95%CI = 1.49-2.44). This was true in men (AOR = 2.21, 95%CI = 1.46-3.34) and in women (AOR = 1.68, 95%CI = 1.24-2.29). LIMITATIONS:Cross-sectional survey preventing causal interpretation. CONCLUSION:In the first ten years following typical retirement age, men and women living alone deserve attention from public health officials and clinicians as they, as a group, have a higher risk of MDE and SI, highlighting the need for targeted mental health interventions and social support strategies.

BACKGROUND:Planned or motivated physical activity (exercise) is amenable to direct modification and has been inversely linked to major depression (MDD), suggesting its potential to support recovery in bipolar disorder (BD). However, it is unclear how quickly exercise may impact emotion. We characterized the association of exercise with subsequent emotional state within hours in persons with a history of mood disorders. METHOD:Euthymic participants aged 11-85 years, diagnosed with BD (n = 110), MDD (n = 157), anxiety without mood disorder (n = 96), or no disorder (n = 96), self-reported their emotional state (sad, anxious, activated, energetic) scaled 1-7 and whether they were exercising four times per day for two weeks via ecological momentary assessment. We characterized the implicit impact of exercise on subsequent emotion within-person and at the group level using dynamic structural equation modeling. RESULTS:Among those with a major mood disorder (BD or MDD), exercise was associated with a strong reduction in subsequent anxiety (-1.706 (95% Credible Interval -2.296, -1.048)), overall and in males and females. However, exercise was not associated with subsequent changes in sad, activated, or energetic feelings. Exercise-emotion dynamics did not differ significantly between individuals with BD compared to MDD, Anxiety without Mood, or no disorder. However, there was variation at the individual within-person level in BD subtypes. CONCLUSION:Exercise appears to drive beneficial impact on emotional state within hours in persons with BD or MDD-particularly by lowering anxiety. Independent replication and clinical trials are needed to draw conclusions about specificity by mood disorder subtype.

Background: Mental disorders are highly prevalent among students worldwide. This study aims to examine comorbidity and temporal associations between mental disorders among students. Methods: The study included 72,288 students from 18 countries as part of the World Mental Health International College Student (WMH-ICS) Initiative, with cross-sectional data collected between 2017 and 2023. Screening for common DSM-5 disorders was conducted using validated screening measures. Latent variables were examined using exploratory principal axis factor analysis on a correlation matrix among the lifetime mental disorders. Based on age-of-onset information, multivariable poisson regression models were used to examine associations of prior disorders with the first onset of other disorders. Results: 27.0 % of students screened positive for only one lifetime disorder, 17.1 % for two, 10.9 % for three, and 10.6 % for 4+ disorders. In the factor analysis, three latent variables were found, comprising: internalizing disorders (generalized anxiety disorder, major depressive episode, post-traumatic stress disorder, and panic disorder), substance use disorders (drug use disorder and alcohol use disorder), and externalizing disorders (attention deficit/hyperactivity disorder and mania/hypomania). Prior internalizing and externalizing disorders were associated with the subsequent first onset of all other disorders with risk ratios ranging from 1.5-7.5. Substance use disorders were less consistently associated with the subsequent first onset of other disorders, but alcohol use disorder was associated with the first onset of drug use disorder and vice versa. Conclusions: Mental disorder comorbidity is common among students, and students with disorders across the internalizing and externalizing spectrum have an increased risk of future mental disorder comorbidities.

BACKGROUND:Although heightened anxiety associated with social interaction or evaluation is the core diagnostic criterion for social anxiety disorder (SAD), there is growing evidence that SAD is characterized by more pervasive reactivity beyond social situations. We employed Ecological Momentary Assessment (EMA) to describe the affective dynamics and emotional reactivity to daily events in a community-based sample of adults with SAD compared with other anxiety disorders, and controls without anxiety or mood disorders. METHODS:A sample of 236 adults with a lifetime diagnosis of SAD (n = 53), other anxiety disorders (n = 120), and no mood or anxiety disorder (n = 63) based on comprehensive diagnostic interviews answered brief electronic interviews that assessed daily life events and mood and anxiety symptoms four times a day for two weeks. Linear mixed models were used to quantify reactivity to daily life events. RESULTS:Persons with SAD had higher average levels of sad and anxious mood than those with other anxiety disorders or controls. Irrespective of comorbid mood disorders, people with SAD also demonstrated significantly greater decreases in both sad and anxious mood following positive events, and a greater increase in anxious mood following negative, particularly non-social events. CONCLUSIONS:Our findings regarding pervasive reactivity beyond the social context in people with SAD confirm the need for broader conceptualization of this disorder as well as expansion of interventions beyond the social context. This work also demonstrates the utility of EMA as a powerful tool to track individual variability and reactivity in daily life that can inform etiology, treatment and prevention.

Background: The objective of the study was to investigate the prevalence of suicidal ideation disclosure over the past two decades in nationally representative samples of the general population, and to identify factors associated with disclosure. Methods: Data were drawn from consecutive nationally representative cross-sectional Health Barometer surveys. The 2000, 2005, 2010, 2014, 2017, and 2021 waves were pooled to examine disclosure among those who reported 12-month suicidal ideation. Logistic regressions were performed to identify factors associated with the odds of disclosure. Results: Across all waves (n = 124,124), 6014 of adults (4.7 %) reported 12-month suicidal ideation, and among them, 49.7 % talked to someone about it. Disclosure was 39 % in 2000, 44.6 % in 2005, 49.9 % in 2010, 52.8 % in 2014, 47.2 % in 2017, and 64.8 % in 2021. Female gender, a prior suicide attempt, higher education, inactive status, and younger age were associated with significantly greater odds of disclosure. Each survey wave was also associated with a greater likelihood of disclosure when compared to 2000, 1.31 (95 % CI, 1.08-1.59) in 2005, 1.69 (95 % CI, 1.38-2.07) in 2010, 1.89 (95 % CI, 1.52-2.34) in 2014, 1.47 (95 % CI, 1.21-1.79) in 2017, and 2.99 (95 % CI, 2.43-3.68) in 2021. Limitations: Cross-sectional surveys. Conclusions: In the general population of France, adults with suicidal ideation were increasingly more likely to disclose their ideation to someone in recent years. Factors associated with odds of disclosure should inform national suicide prevention strategies to identify subgroups who remain less likely than others to disclose their ideation.

Objective: The objective of the present study is to determine whether living alone is associated with major depression among men and women after adjusting for sociodemographics known to be associated with depression. Methods: Data from the 2005, 2010, 2017, and 2021 nationally representative cross-sectional French Health Barometer surveys were pooled covering n = 71,168 adults ages 18 to 75. Logistic regressions were performed to identify associations between 12-month major depressive episode and living alone overall, and stratified by sex. Results: An increasing portion of adults 18 to 75 lives alone in France: 11.2 % in 2005, 16.7 % in 2010, 17.4 % in 2017, and 19.0 % in 2021. Among men, in our study, those living alone represented 10.3 % in 2005 to 20.0 % in 2021, among women, 12.1 % in 2005 and 18.0 % in 2021. Men are more likely than women to live alone before age 55, the reverse is true thereafter. In parallel, the prevalence of depression has increased from 8.0 % in 2005 to 13.3 % in 2021. In multivariable models adjusting for age, sex, education, occupation, income level, urbanicity and study wave, living alone was associated with higher odds of depression (AOR=1.50, 95 %CI=1.41–1.60). No significant interactions were found for living alone x sex, while living alone was significantly associated with depression only among those 25 or older. Limitations: Cross-sectional surveys. Conclusion: Living alone is becoming more frequent and is a strongly associated with major depression. This finding should raise attention to groups of men and women at increased risk of mental health problems.

PURPOSE:This study investigates associations of childhood adversities (CAs) with lifetime prevalence, 12-month prevalence, and 12-month persistence of mental disorders in a large cross-national sample of university students. METHODS:Data came from epidemiologic surveys carried out by the World Mental Health International College Student (WMH-ICS)Initiative across 18 countries (n=60,719). The web-based surveys screened for lifetime and 12-month prevalence and age-of-onset of common DSM-5 disorders (Major Depressive Disorder, Bipolar I/II Disorder, Generalized Anxiety Disorder, Panic Disorder, Posttraumatic Stress Disorder, Alcohol and Drug Use disorders, Attention-Deficit/Hyperactivity Disorder) and five types of CAs (family dysfunction, emotional abuse, physical abuse, sexual abuse, neglect). Multivariable Poisson regression models estimated associations of CA type, number, and frequency with disorders. RESULTS:The majority of incoming students reported exposure to at least one CA (64.9%), including 50.0 % family dysfunction, 42.2 % emotional abuse, 21.2 % physical abuse, 18.8 % neglect, and 5.0 % sexual abuse. Lifetime and 12-month disorders were significantly associated with CAs in multivariable models, although associations with disorder persistence were weaker. Population attributable risk proportions of 12-month disorders associated with CAs were in the range of 40.7-61.0 % for anxiety and mood disorders and 13.5-55.2 % for substance use disorders. CONCLUSION:Six out of ten university students arrive at university having been exposed to CAs. These students have substantially higher risk of mental disorders than other students, primarily due to associations with lifetime risk rather than persistence. Given the considerable distress and impairment caused by mental disorders, these results underscore the need for primary and secondary prevention efforts.

Ecological Momentary Assessment (EMA) is widely used in mental health research to capture internal states and experiences as they occur in real-world settings, yet the lack of standardization in EMA content, study design, analytical approaches and data collection platforms has hindered comparability across studies and limited progress in mental health research. We have developed standardized, open-source tools for EMA with the Real-time Ecological Assessment of the Context of mental and physical Health (REACH) at the National Institutes of Health Clinical Center, to characterize dynamic profiles of physical and mental health across the lifespan. The REACH applet is integrated into Curious, a secure, open- source, configurable, and scalable platform through a collaborative effort with the Child Mind Institute. We describe the content, materials, and methods of REACH shared under a Creative Commons license to promote access and harmonization of these tools in global settings across the life span.

OBJECTIVE:The objectives of the study were to examine the prevalence of family dysfunction childhood adversities (CAs) by sex in a nationally representative sample and to investigate the sex-specific association of CAs with lifetime suicide attempts. METHODS:Data were drawn from the 2005, 2010, and 2017 nationally representative cross-sectional French Health Barometer surveys (n = 47,105) to examine exposure to three types of CAs and their association with lifetime suicide attempts. Logistic regressions were performed to identify associations of every exposure combination with the odds of suicide attempts overall, and stratified by gender. RESULTS:Overall, 43.9 % of adults reported exposure to at least one type of CA: 16.4 % parental separation, 22.4 % parental illness or death, and 22.5 % parental discord. Women reported exposure to CAs more frequently (54.1 %) than did men (45.9 %), (χ2 = 132,00, df = 1, p < 0.0001). Overall, 8.7 % of women and 3.7 % of men reported a lifetime suicide attempt. In multivariable models, female sex (AOR = 2.13, 95 %CI = 1.96-2.32) and each form of exposure to CAs was associated with higher odds of reporting a lifetime attempt with exposure to all three types of CAs associated with the highest odds of lifetime attempt (AOR = 5.15, 95 %CI = 4.37-6.07). Parental discord held the strongest association with attempts, compared to illness/death or separation. In stratified analyses, CAs were equally associated with attempts among men and women. LIMITATIONS:Cross-sectional surveys. CONCLUSIONS:Parental discord was found to be highly prevalent in the general population and strongly associated with suicide attempts. No sex-specific associations were observed in the association of adversity types and number with attempts.

Mental health disparities have been reported among sexual minority individuals; minority stress theory posits that such disparities are a result of stigma and discrimination. We estimated the prevalence of mental disorders across sexual orientation groups among first-year college students and whether differences across sexual orientation groups varied by gender and country-level LGBTQ+ (lesbian, gay, bisexual, transgender, queer) social acceptance. Using data (N = 53,175; 13 countries) from the World Mental Health Surveys International College Surveys, we performed multilevel logistic regressions to estimate the associations between sexual orientation (i.e., heterosexual, heterosexual with same-gender attraction [SGA], gay/lesbian, bisexual, asexual, questioning, and other) and five twelve-month DSM-5 disorders (major depressive disorder, generalized anxiety disorder, panic disorder, alcohol use disorder, drug use disorder). Heterosexual students with SGA (AORs 1.30-2.15), gay/lesbian (AORs 1.49-2.70), bisexual (AORs 2.26-3.49), questioning (AORs 1.38-2.04), and "other" (AORs 1.76-2.94) students had higher odds of all disorders compared to heterosexual students with no SGA; asexual students did not. Significant interactions with gender show that the gender difference in prevalence was greater among bisexual individuals for most disorders and among all sexual minorities (except "other") for drug use disorder. Significant interactions with country level LGBT+ social acceptance showed some sexual minority groups had lower odds (AORs 0.83-0.95) of disorder as country-level acceptance increased. These findings provide further evidence of mental disorder disparities across a wide range of sexual orientations and how these disparities vary by gender and societal LGBTQ+ acceptance in students from diverse countries.

OBJECTIVE:To investigate the associations of demographic variables, childhood adversities (CAs), and mental disorders (MDx) with onset, transition, and persistence of suicidal thoughts and behaviors (STB) among first-year university students. METHOD:Poisson regression models within a discrete-time survival framework were constructed using web-based self-report survey data from 72,288 incoming university students across 18 countries (response rate=20.9%; median age=19 years, 57.9% female, 1.4% transgender, 21.0% non-heterosexual). These models examined the associations of four demographic variables, five CAs, and eight MDx with STB outcomes. RESULTS:Lifetime prevalence of suicidal ideation, plans, and attempts was 47.0%, 26.0%, and 9.6%, respectively; 12-month estimates were 30.6%, 14.0%, and 2.3%. In unadjusted analyses, associations were strongest between lifetime onset of suicidal ideation and CAs (RR range 4.4-7.0), particularly parental psychopathology (relative risk [RR]=7.0 [95% CI 6.5-7.7]), followed by MDx (RR range 1.3-3.0). Of the demographic subgroups, transgender students had highest risk of STB (lifetime ideation onset RR=2.4 [2.3-2.6]; ideation-to-attempt transition RR=1.5 [1.3-1.8]). In fully adjusted models, strongest predictors of lifetime ideation onset were emotional abuse (RR=2.1 [1.9-2.2]), major depressive disorder (RR=2.0 [1.9-2.1]), and bipolar disorder (RR=1.8 [1.6-2.0]). Ideation-to-attempt transition remained most strongly associated with panic disorder (RR=1.5 [1.3-1.7]), bipolar disorder (RR=1.4 [1.2-1.7]), and sexual abuse (RR=1.4 [1.2-1.7]). Most predictors were significantly but weakly associated with persistence of ideation and plan, while only physical abuse remained associated with repeated suicide attempts (RR=1.3 [1.0-1.8]). CONCLUSION:CAs and MDx are strong predictors of both onset of and transition within the STB spectrum, underscoring the importance of implementing early-life prevention interventions.

BACKGROUND:Risky alcohol use is frequent among college students and can be associated with functional outcomes. Bidirectional associations have been shown between alcohol use and the stability of romantic relationships, though little is known about the longitudinal association between risky alcohol use and romantic relationships in college and about college students' perceived stress regarding one's love life. Objectives: The present study aims to explore these relationships both cross-sectionally and at one-year follow-up. METHOD:Data were drawn, from the French portion of the World Mental Health International College Student Survey initiative (WMH-ICS). First-year college students who completed an online survey (n = 1,624) and a second survey at one-year follow-up (n = 727) were included. Current romantic relationship status and stress regarding one's love life, past-year risky alcohol use, lifetime presence of DSM-5 mental health disorders and sociodemographic correlates were assessed. RESULTS:Risky alcohol use was cross-sectionally associated with dating in multivariate models adjusting for lifetime mental disorders (aOR = 1.70, 95%CI = 1.31-2.20), and in particular with unsteady relationships (aOR = 2.87, 95%CI = 2.01-4.10), but was no longer associated with both one year later. Risky alcohol use was, however, not associated with severe perceived stress regarding one's love life in multivariate models adjusting for lifetime mental disorders in both cross-sectional and longitudinal analyses, while it was associated in bivariate models for both analyses. CONCLUSIONS:These findings extend our understanding of the association between excessive drinking and romantic relationship patterns among college students underlying the importance of comorbid disorders.

Studies indicate that non-heterosexual young adults experience higher rates of mental health problems in various settings. This study seeks to further explore these associations, distinguishing heterosexual, gay/lesbian, bisexual and individuals questioning their sexual identity. Data were drawn from the French portion of the World Mental Health International College Student survey initiative (n = 3,545). Logistic regressions were performed to estimate the associations of sexual orientation with 12-month mental disorders and suicidal ideation and behaviors. Overall, 81.6% (n = 2,894) of students identified as heterosexual, 2.9% (n = 103) as gay/lesbian, 8.5% (n = 302) as bisexual and 6.9% (n = 246) stated questioning their sexual orientation. In adjusted models, compared to heterosexuals, students identifying as bisexual reported greater odds of major depression, panic disorder, drug use disorder and suicidality, gay/lesbian students were more likely to present with panic disorder, suicidal ideation and plans, and students questioning their sexual orientation were at greater risk for generalized anxiety disorder, suicidal ideation, and plans. The study confirmed higher rates for mental health disorders for non-heterosexual young adults, with little evidence of significant differences between minority subgroups.

The study examines the prevalence of 12-month suicidal thoughts and lifetime suicide behaviors among young adults between 2000 and 2021. Data were drawn from the Health Barometer survey, a cross-sectional survey on a French national representative sample. The 2000, 2005, 2010, 2014, 2017, and 2021 survey waves were pooled to examine time trends in 12-month suicidal thoughts and lifetime suicidal behaviors among respondents aged 18 to 25 (n = 13,326), categorized based on sex and on their occupational status: students, those employed, and those who are neither in employment, education or training (NEETs). The 12-month prevalence of suicidal ideation among young adults in 2021 (6.8 %) is no different from that of 2000 (7.0 %), despite a U-shape curve in between. In contrast, the overall prevalence of lifetime suicide attempts was significantly higher in 2021 as compared to what was observed on average in the previous 21 years. In multivariate models, females and NEETs were overall at greatest risk for suicidal ideation and suicidal behaviors. Additional attention and prevention efforts are needed to reach young adults who are neither in employment, education or training.

The objective of the study is to examine perceived helpfulness of medication and psychotherapy among adults with suicidal ideation. Data were drawn from the 2017 Health Barometer, a nationally representative French survey (n = 25,319). Overall, 4.7% (n = 1,148) reported suicidal ideation in the prior 12 months. Logistic regressions were used to examine factors associated with perceived helpfulness among individuals reporting suicidal ideation in the past year who had received medication (n = 590) or psychotherapy (n = 247). Overall, 80.4% (n = 489) reported that medication was/is helpful, and 56.5% (n = 149) reported psychotherapy helped them a lot. In adjusted models, those with major depression were more likely than those without (AOR = 2.18, 95%CI = 1.39-3.421) to perceive medication as helpful. Those with a recent suicide attempt were less likely to report medication as helpful (AOR = 0.42, 95%CI = 0.21-0.84). Receiving psychotherapy was significantly associated with perceived helpfulness of medication (AOR = 1.89, 95%CI = 1.09-3.29). Additional larger studies are needed in France to assess perceived helpfulness by type and adequacy of psychotherapy received.

Introduction: The aim of the present study is to estimate the lifetime prevalence of suicidal ideation, plans, and attempts in a regional representative sample and the association of these outcomes with sociodemographic factors, prior mental disorders, and childhood adversities. Material and methods: The PEGASUS -Murcia project is a cross-sectional survey of a representative sample of adults in Murcia that is part of the WHO World Mental Health Survey Initiative. The Composite International Diagnostic Interview (CIDI 3.0) was administered face-to-face to 2621 participants (67.4% response rate). The main outcomes were suicidal ideation, plans, and attempts. Lifetime prevalence, age of onset, and risk factors (sociodemographic variables, mental disorders, and childhood adversities) were examined using multiple discrete -time survival models. Results: Lifetime prevalence of suicidal ideation, plans and attempts were 8.0% (standard error, SE: 1.1), 2.1% (SE: 0.3), and 1.2% (SE: 1.1), respectively. Prevalence of any childhood adversities was 22.1% (SE: 1.3) in the total sample and, even higher, among those with suicide related outcomes (ranging between 36.8% and 53.7%). Female sex, younger age, prior (to onset of the outcome) lifetime prevalence of mood disorders, number of mental disorders, and exposure to childhood adversity were associated with significantly increased odds of suicidal ideation and plans. Conclusions: Lifetime prevalence estimates of suicidality are similar to those in community epidemiological surveys. Childhood adversities and mental disorders, especially mood disorders, are important risk factors for suicidality. Early detection of these adversities and disorders should be targeted in suicide prevention programs. (c) 2020 Sociedad Espan similar to ola de Psiquiatria y Salud Mental (SEPSM). Published by Elsevier Espana, S.L.U. All rights reserved.

Background This study investigates associations of several dimensions of childhood adversities (CAs) with lifetime mental disorders, 12-month disorder persistence, and impairment among incoming college students. Methods Data come from the World Mental Health International College Student Initiative (WMH-ICS). Web-based surveys conducted in nine countries (n = 20 427) assessed lifetime and 12-month mental disorders, 12-month role impairment, and seven types of CAs occurring before the age of 18: parental psychopathology, emotional, physical, and sexual abuse, neglect, bullying victimization, and dating violence. Poisson regressions estimated associations using three dimensions of CA exposure: type, number, and frequency. Results Overall, 75.8% of students reported exposure to at least one CA. In multivariate regression models, lifetime onset and 12-month mood, anxiety, and substance use disorders were all associated with either the type, number, or frequency of CAs. In contrast, none of these associations was significant when predicting disorder persistence. Of the three CA dimensions examined, only frequency was associated with severe role impairment among students with 12-month disorders. Population-attributable risk simulations suggest that 18.7-57.5% of 12-month disorders and 16.3% of severe role impairment among those with disorders were associated with these CAs. Conclusion CAs are associated with an elevated risk of onset and impairment among 12-month cases of diverse mental disorders but are not involved in disorder persistence. Future research on the associations of CAs with psychopathology should include fine-grained assessments of CA exposure and attempt to trace out modifiable intervention targets linked to mechanisms of associations with lifetime psychopathology and burden of 12-month mental disorders.

Background: Population-based studies have shown that less than one in two individuals reporting suicidal ideation also report past-year mental health service use. Only a few studies have looked at different types of providers consulted. There is a need to better understand the factors associated with different provider combinations of mental health service use in representative samples of individuals with suicidal ideation. Aims: The aim of the current study is to assess, using Andersen’s model of healthcare seeking behaviors, the predisposing, enabling and need factors associated with type of mental health service use in adults with past-year suicidal ideation. Methods: Data were drawn from the 2017 Health Barometer survey, a representative sample of the general population aged 18 to 75 years, among whom 1,128 respondents had reported suicidal ideation in the past year were analyzed. Past-year outpatient mental health service use (MHSU) was categorized into mutually exclusive groups as no use, general practitioner (GP) only; mental health professional (MHP) only; and both GP and MHP. Multinomial regression analyses were used to model mental health service use as a function of predisposing, enabling and need factors. Results: Overall, 44.3% reported past-year MHSU and this was higher in females than males (49.0% vs. 37.6%). Prevalence of GP only use in the overall sample was 8.7%, consulting with GP and MHP was 21.3%, consulting with MHP only was 14.3%. Higher education was associated with increased MHP use. Residing in a rural area was associated with increased GP only use. Presence of a suicide attempt within the year, a major depressive episode and role impairment were associated with consulting a GP and MHP, and MHP only, but not GP only. Conclusions: When controlling for need and predisposing factors, socio-economic factors related to employment and income were associated with higher levels of consulting with mental health professionals.

Purpose While the association between childhood adversities (CAs) and negative mental health outcomes is robustly supported throughout the epidemiological literature, little is known about their contribution to the persistence of role impairment. The present study aims to investigate the association of three facets of CAs with the persistence of severe role impairment among college students using a follow-up design.Methods Data were drawn from the French portion of the World Mental Health International College Student Initiative. Students who completed both the baseline and 1-year follow-up surveys were included (n = 1,188). Exposure to 12 types of CAs before the age of 18 was assessed at baseline, and 12-month role impairment and 12-month mental disorders were assessed at baseline and follow-up. Logistic regressions estimated associations by jointly using types, number of types, and cumulative frequency of exposure to CAs as predictors.ResultsAt baseline, 27.6% of students reported any severe role impairment. Among them, 47.5% reported the persistence of any impairment at one year. In models adjusted for 12-month mental disorders, only the frequency of CAs was associated with the persistence of impairment, namely college-related and other work impairment (aOR = 1.17, 95% CI [1.01, 1.35]).ConclusionRole impairment is prevalent among college students, and studies are needed to better understand its persistence. Beyond the primary prevention of early stressors, screening for and treating mental health problems during college may help reduce the impact of CAs on the persistence of role impairment.

The goal of this talk will be to examine the role of objectively assessed sleep, physical activity, and circadian rhythms, and their interrelationships with mood and anxiety disorders as potential early markers of bipolar disorder and MDD in 3 studies of offspring of parents with mood disorders.