Purpose: To investigate the relationship between intraoperative anesthesia-related factors and postoperative complications in patients undergoing emergency abdominal surgery, and to iden-tify risk factors for these postoperative complications.Methods: We retrospectively analyzed 942 emergency surgery patients who underwent general anesthesia and emergency abdominal operations at Jiangsu Province Hospital during the period September 2015 to December 2016. Logistic regression analysis was performed to analyze the association between preoperative or intraoperative parameters and postoperative complications.Results: Among the 942 patients whose data were analyzed, 226 (24.0%) had major postoperative complications within 30 days after surgery. The most common postoperative complications were respiratory complications (31.8% of those experiencing complications). After adjusting for the role of multiple confounding factors, multivariable analysis showed that the independent risk factors for postoperative complications were patient age (OR 1.648; 95% CI 1.352-2.008), the ASA classification (OR 3.220; 95% CI 2.492-4.162), intraoperative hypotension lasting more than 20 min (OR 2.031; 95% CI 1.256-3.285), intraoperative tachyarrhythmias (OR 2.205; 95% CI 1.114-4.365), and the surgical level (i.e. type and difficulty level) [OR 1.895; 95% CI 1.306-2.750].Conclusion: Prolonged intraoperative hypotension (>20 min) and the occurrence of tachyar-rhythmias are independent risk factors for postoperative complications in patients who undergo emergency abdominal surgery. During hemodynamic management of these patients, systolic blood pressure should be controlled to within 20% of the baseline value to reduce the risk of postoperative complications. In addition, a higher patient age, higher ASA grade, and a higher surgical classification level also significantly increase the risk of postoperative complications.
In Thomson scattering (TS) diagnostic system, the stray light greatly affects the signal-to-noise ratio (SNR). The suppression issue is particularly severe for the low density and low temperature plasma due to very few scattered photons and narrow line broadening. The traditional methods, such as Brewster window, beam dump and transmission pipe with black-coated internal surface, have been adopted in the stray light suppression system on our Linear Magnetized Plasma (LMP) device. Moreover, an assembly of tapered apertures are placed in the optical path. Via numerical simulation, the optimal configuration of the adjustable aperture tube (size, location, and orientation) that provide the best suppression has been found. Numerical results show that the optimal aperture group with 6 mm and 8 mm tapered apertures can maintain over 97% transmission rate of the main laser energy while reducing stray light by 99.6%.
In addition to the magnetic confinement fusion plasma, Thomson scattering has been applied to measure electron density and temperature of low-temperature plasmas. Based on a linear magnetized plasma device, a set of Thomson scattering diagnostic system is designed to diagnose the plasma with n(e) = 10(18)-10(19) m(-3) and T-e = 2-5 eV. Due to low plasma temperature and density, this diagnostic system needs high spectral resolution and collection efficiency to meet the requirements of electron velocity distribution function measurements. Through the bench test, it is confirmed that the spectral resolution reaches 0.01 nm, and theoretical collection efficiency is high enough to obtain a Thomson scattering spectrum by 1000 accumulations.
Objectives To assess the prevalence of postoperative pulmonary complications (PPCs), the perioperative factors associated with PPCs, and the association of PPCs with postoperative outcomes in ovarian cancer patients undergoing cytoreductive surgery. Methods A retrospective analysis was conducted on patients who underwent cytoreductive surgery in our hospital, between September 2017 and January 2021, and patient medical records were reviewed to collect relevant clinical information. Univariable and multivariable analyses were used to identify significant risk factors for PPCs. Analysis of the association of PPCs with postoperative outcomes, mortality and 30-day readmission, was undertaken utilizing propensity score-matched controls and multivariable logistic regression model. Results Final analysis was performed with 268 ovarian cancer patients after cytoreductive surgery, among whom the incidence of PPCs was 26.9%, and the most frequent pulmonary complication was pleural effusion. According to the multivariate analysis, the intraoperative fluid infusion volume (L) (odds ratio (OR) 1.34; 95% confidence intervals (CI) 1.01–1.77; P = 0.040), diameter size of diaphragmatic resection (cm) (OR 1.16; 95% CI 1.06–1.28; P = 0.002), and surgical complexity scores (OR 1.26; 95% CI 1.13–1.42; P < 0.001) were significantly associated with the development of PPCs. The multivariable logistic regression analyses with propensity-matched controls demonstrated that the occurrence of PPCs significantly increased the risk of 30-day readmission (OR 6.01; 95% CI 1.12–32.40; P = 0.037) and did not significantly affect inpatient mortality. Conclusion Ovarian cancer patients undergoing cytoreductive surgery, especially those with diaphragmatic resection or higher surgical complexity scores, represent a high-risk population for PPCs. In addition, goal-directed fluid therapy is vital to reducing the occurrence of PPCs in patients at risk. PPCs were not associated with in-hospital mortality but were significantly associated with an increased risk of 30-day readmission after cytoreductive surgery.
Objective To investigate the relationship between the occurrence of adverse events during operation and postoperative complications in emergency general surgery patients, and to analyze the risk factors of postoperative complications.Methods We retrospectively analyzed 689 e-mergency general patients undergoing general anesthesia emergency surgery during the period of Sep 1,2015 to Sep 1,2016 in the First Affiliated Hospital of Nanjing Medical University.The clinical fac-tors that may influence the outcomes and postoperative complications were collected and analyzed using univariate analysis and multivariate Logistic regression analysis.Results Among the 689 patients enrolled in the study,there were 165 (23.9%)patients who had major complications within 30 days after surgery.The most common postoperative complications were respiratory complications (40.6%).The inde-pendent risk factors of postoperative complications including age (OR 1.880,95%C I 1.448-2.440),ASA classification (OR 3.303,95%C I 2.303-4.736),intraoperative hypotension duration more than 20 minutes (OR 2.501,95%C I 1.387-4.510),intraoperative rapid arrhythmia (OR 2.173,95% C I 1.002-4.711) and surgical level (OR 1.814,95% C I 1.060-3.103).Conclusion Emergency general surgery in patients with intraoperative hypotension duration more than 20 minutes and the occurrence of rapid arrhythmia are independent risk factors for postoperative complications.During the circulation man-agement of emergency surgical patients,the reduction of systolic blood pressure in the operation should be controlled within 20% of the base value to reduce the risk of postoperative complications.