Research studies in medicine, genetics and process monitoring technology generally go together with advances in nano-engineering. Furthermore, advances in engineering, control and automation on the nano scale first enable so far impossible studies in molecular and cellular biology. This fruitful interaction leads to the design and development of new setups and methods, which push the boundaries for possible experiments in the area of handling and manipulation of biomaterials. In our paper the latest work on two areas of this research focus is shown. 1) Within the last years, the AFM was used for the handling and manipulation of biomaterials. However, the automation to use the AFM for industrial processes needs a robust and accurate automation. In this paper we also present the latest work on the automation of AFM based methods. 2) In the future, mobile diagnostics will become more and more important. To enable robust, fast and precise systems, new methods for the design and structuring of the necessary bio-components are needed. For this, a possible approach to structure bio-components from several nm up to a few μm is presented in this paper as well. 3) First simulations and principles for the design of a new signal acquisition unit are shown, to set up diagnostic systems without complex optical setups or fluorescence dyes.

The importance of nanoelectronics for the future is well-recognized. Next-generation nanoelectronic technologies, for the usage in intelligent implants, intelligent drugs or even ICs for the coupling of destroyed nerves, are sensitive to dimensional change. Therefore, an appropriate packaging is essential to the success or failure of these technologies. In this paper current work to use DNA as a template for bonding at the nanoscale and for novel nanoelectronic components is presented. Moreover, a method is presented, which enables the handling and manipulation of DNA at dry conditions, thus enabling the feasible usage for industrial purposes as well as for science. For this the necessary steps, starting with the immobilization and choice of useable nanowires, followed by the extraction and separation of these wires, the coarse positioning, the immobilization onto the target substrates as well as a proper fine tuning at the target are presented.