The work analyzes the results of study of lipid metabolism in 53 patients who underwent operation for pancreatogenic peritonitis. The blood for the test was collected from the portal vein, the hepatic vein, and the aorta which made it possible to appraise metabolism in the liver according to the "entry-exit" blood flow system. It is shown that due to pancreatogenic toxemia, toxemic hepatocytic dyslipoproteinemia develops in patients with pancreonecrosis and persists in the late period. As a consequence of such a condition of lipid metabolism, early atherosclerotic damages to the arteries of the heart and brain and the peripheral arteries occur in patients after pancreonecrosis. The fate of patients was studied 8-10 years after the operation. The nature of atherosclerotic manifestations of toxemic hepatocytic dyslipoproteinemia in the late period after recovery from destructive pancreatitis was determined on the basis of study of central and peripheral hemodynamics.
Patients with cholelithiasis are treated by the method of extracorporeal lithotripsy. The technique of the combined use of two lithotriptors with different modes of shock wave generation (electrohydraulic and electromagnetic) is described. As a result of treatment the number of skin petechiae decreases as do transitory hematuria and manifestations of hepatic colic and acute pancreatitis, whereas mechanical jaundice and acute cholecystitis develop with the same frequency. The number of recurrences of cholelithogeny in patients with hyperlipidemia is 8 times higher than in the control, which indicates a clear connection between hyperlipidemia and stone formation in patients after extracorporeal biliary lithotripsy.
The results of treatment of patients with uncomplicated cholelithiasis by extracorporeal lithotripsy are analyzed. Clinical evidence confirming the relationship between hyperlipidemia and cholelithiasis is presented. The number of recurrences is foudn to decrease considerably after extracorporeal lithotripsy for judicious correction of hyperlipoproteinemia.
The authors analyse the results of endovascular angioplasty of the pelvic and lower limb arteries in 147 patients of various age suffering from arteriosclerosis obliterans. It was found that the results of endovascular angioplasty depended on the state of the lipid balance. The necessity for correcting the shifts in the lipid metabolism is shown. The article evaluates the results of dyslipidemia correction by dietotherapy, pharmacotherapy, and operation for partial ilio-shunting in patients with arteriosclerosis obliterans of the pelvic and lower limb arteries. The efficacy of the listed methods of treatment are analysed according to the severity of dyslipidemia.