The photophysical properties of five dyes, i.e., perylene, anthracene, aminoanthracene, 1,6-diphenylhexatriene, and 7-diethylamino-4-methylcoumarin, in solvent and attached to the poly(methyl methacrylate) (PMMA) polymer, were studied via DFT and TD-DFT calculations. Their absorption and emission spectra were calculated, while for the PMMA-dye systems, their absorption spectra were measured experimentally, in good agreement with the calculated ones. In the PMMA-dye systems, charge transfer from the dye to PMMA was observed, and in the case of perylene, electron transfer from its ground state was also observed. It was found that the PMMA-dye systems can interact photochemically via laser illumination, and provided that the charge transfer will be enhanced by using the appropriate laser parameters, the systems may be candidates for the design of materials for specific nanopatterning needs.

AbstractHalide organic–inorganic perovskites (HOIPs) are a promising class of materials for neuromorphic computing and processing systems demonstrating a variety of resistive switching (RS) mechanisms. HOIPs have been used as active layers in two‐ and three‐terminal synaptic devices reporting high performance in metrics of speed and energy consumption. Nevertheless, halide perovskites suffer from poor ambient stability and reproducibility. In this work, a highly robust double memristor based on two active layers forming a stacking heterojunction is demonstrated. In particular, the functional layer consists of a molybdenum oxide‐molybdenum sulfide compound (MoO3‐MoS2) and a quadruple cation perovskite (RbCsMAFA) deposited on top showing favorable band alignment for the specific application. The double memristor based on the MoO3‐MoS2/RbCsMAFA heterojunction exhibits impressive and stable resistive switching behavior with endurance of 100 cycles, high retention of 2 × 104 s, high environmental stability maintaining its memristive behavior for 1 month, and excellent artificial synaptic functions. The robust device also exhibits good thermal stability maintaining the memristive characteristics at 85 °C, as well as good photonic memristive behavior with an improved ON/OFF ratio under constant illumination. Here it is proven that the proposed double memristor is a promising candidate for artificial synapses and neuromorphic computing systems.

Charge injection and transport interlayers based on artificial green carbon materials are imperative for a sustainable future of many classes of optoelectronic devices, including organic light-emitting diodes (OLEDs). Especially, porphyrin derivatives can act as efficient energy and charge funnels mimicking their successful photosynthetic function. Here, we report on the application of a novel green carbon material, in particular, a zinc porphyrin derivative bearing an amidine functional group (referred to as ZnP-amidine), as an electron transport material in fluorescent OLEDs based on a green-yellow co-polymer emitter. ZnP-amidine is processed from environmental friendly solvents without any annealing requirements thus being suitable for low-cost sustainable optoelectronics. It is applies as an ultra-thin interlayer between the aluminum cathode and the emissive layer to enable efficient electron transport and stable performance. This work paves the path towards low-cost green carbon materials inspired by natural processes for organic optoelectronics.

Although this opinion paper tracks the career of Mike Hatzakis (as he liked to be called), and explains the impact he made on the IT industry, it is not intended to be comprehensive insofar as the work that was underway during his career is concerned. Thus, the intent is not to cite all relevant work in the field of Semiconductor lithography, where Mike made such an impact, but to provide a historic and human perspective of this remarkable man from the land of the Minotaur (Crete) and his career, the work he championed in his labs in the US and later Greece and his very human approach to science, technology, and to people.Unlabelled Image

Although organic light-emitting diodes (OLEDs) are considered a mature technology, further enhancements in their efficiency are of paramount importance for advancing their incorporation in high-quality displays and flexible, wearable, electronic devices. In this regard, we propose an innovative approach, focusing on strategic modifications to the hole transport layer (HTL) through the integration of core-shell nanoparticles. Silver nanoparticles (Ag-NPs) encapsulated in a tungsten polyoxometalate compound (POM) are embedded within the prototype poly(3,4-ethylenedioxythiophene)-poly(styrenesulphonate) (PEDOT:PSS) to form the modified HTL. Our work reveals the pivotal plasmonic role of Ag-NPs in enhancing OLED device performance based on commercially available conjugated polymers. Comprehensive analyses, including UV-Vis absorption spectroscopy, atomic force microscopy, photoluminescence spectroscopy, and electrical measurements, confirm the influence of the POM encapsulated Ag-NPs on improving the device efficiency. This is attributed to the synergistic influence of enhanced hole injection and conductivity and beneficial optical effects (i.e. the Localized Surface Plasmon Resonance (LSPR) and, likely, light scattering of the POM-Ag NPs in the core-shell configuration, depending on their diameter), contributing to enhanced carrier balance and exciton recombination rate. Comparison with POM gold NPs (POM-Au NPs) highlights the distinct advantages of POM-Ag NPs. Our work reveals the potential of this innovative approach to contribute to the evolution of high-performance OLEDs, ensuring a visually compelling and efficient future.

Introduction Achieving successful stabilization in patients with mental disorders often requires the administration of multiple antipsychotic medications, with the increasing prevalence of clozapine in cases resistant to other treatments. Constipation emerges as a particularly troublesome side effect, gradually progressing into a chronic state of gastrointestinal dysfunction, often accompanied by recurrent episodes of paralytic ileus of varying severity. Prucalopride, a 5-HT4 agonist, selectively targets receptors within the intestinal system.This interaction induces muscular contractions and promotes chloride secretion. Literature suggest its potential efficacy in managing constipation induced by clozapine. In light of these observations, we designed and will conduct a randomized controlled trial to evaluate the effectiveness of prucalopride in alleviating constipation in patients who had shown limited responsiveness to conventional laxatives or other conservative treatments Objectives The primary objective of this article is to present the methodology of a randomized control trial assessing the efficacy of prucalopride in the treatment of constipation among patients with mental disorders Methods The study will enroll 60 adult patients with mental disorders who will require more than two antipsychotic medications, including clozapine, for stabilization, and who will be experiencing constipation as a side effect To ensure the validity of the study, the following additional inclusion criteria will be applied: - Patients will have no severe acute medical conditions - Patients will have no history of malignancy - Patients will have no severe respiratory or cardiac diseases - Patients will have negative results from an endoscopic evaluation of the large bowel, ruling out conditions such as irritable bowel syndrome, ischemic colitis, inflammatory bowel disease, or malignant neoplastic disease Following the screening process, the patients will be randomly assigned to one of two treatment groups: Prucalopride Group: Patients in this group will receive prucalopride for the treatment of refractory constipation Conservative Treatment Group: Patients in this group will continue with conservative treatments.The treatment’s success will be determined based on specific endpoints: - Normalization of bowel movements, characterized by having more than five bowel movements per week - Resolution of symptoms related to gastrointestinal dysfunction, including pain, bloating, defecation difficulties, and paralytic ileus Results Following the conclusion of the study, data from both groups will be meticulously collected and subjected to rigorous statistical analysis to identify differences in treatment outcomes between these two therapeutic approachs Conclusions The detailed findings will be presented in a forthcoming article Disclosure of Interest None Declared

Introduction Hyponatriemia can be potentially fatal if it is not corrected immediately. The rapid correction of chronic hyponatriemia can cause demyelinating brain lesions. Objectives A fifty-six year old female was brought to the emergency department of the psychiatric clinic by her daughter, with incomprehensible speech and psycomotor agitation. She was diagnosed several years ago with bipolar disorder, with valproic acid and quetiapine being her current medication. She has been living alone, in a small suburban city. Approximately twenty four hours before her admission to the hospital she visited her daughter, which aligns with the onset of symptoms. Methods After both the brain CT scan and the lab results came back normal, the patient was admitted to the psychiatric clinic of the General Hospital of Corfu. On the fourth day of the patient’s hospitalization - when both her speech and the psycomotor agitation showed signs of improvement- we were informed that three days before her admission to the clinic she visited the emergency department of another hospital where she was treated for hyponatriemia. The patient’s hyponatriemia was corrected over the span of twelve hours by 35 mEq. Results After receiving this information, we ordered a brain MRI scan which revealed a central pontine myelinolysis. The result can explain the clinical symptoms that our patient showcased before her admission and could have been caused by the rapid correction of hyponatriemia. Conclusions The patient’s speech was fully restored after four weeks and there were no symptoms consistent with any psycho emotional disorder. Disclosure of Interest None Declared

Introduction Clozapine is an atypical antipsychotic medication which is mainly used in cases of treatment-resistant schizophrenia. Although it has several advantages over other typical and atypical antipsychotic medication, such as fewer relapses and lowering the risk of tardive dyskinesia and suicide it also has a range of adverse effects which makes compliance an issue for many patients. Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis clinically characterized by painful pustules or nodules that rapidly evolve in ulcers with violaceous, undermined borders and raised periphery. The etiopathogenesis of the disease remains unclear, however PG is usually manifested in the setting of an underlying immune-mediated disease, more commonly inflammatory bowel disease, rheumatoid arthritis and haematological malignancies. Objectives Nevertheless, in the literature there are scarce reports of drug-induced PG. Methods We present the case of a 56-year-old woman with a diagnosis of refractory schizophrenia on clozapine treatment for 4 months, who was admitted to the emergency department for a skin eruption localized on the trunk, genital area and extremities. The clinical examination revealed numerous, discrete erythematous macules, papules and plaques with central necrosis, and multiple, sharply marginated ulcers with undermined, red to purple border. Further physical examination disclosed no systemic findings and laboratory analyses and skin biopsy were performed. Results On work-up, white blood cell count and C-reactive protein (CRP) were elevated, while blood and pustule cultures were negative. Histologic examination revealed dermal necrosis and inflammation, features consistent with the diagnosis of PG. The pathergy test was positive. Image: Image 2: Image 3: Conclusions Pyoderma gangrenosum is a rare autoinflammatory skin disorder of unknown etiology. The pathogenesis of the disease is not well understood, but drug-induced PG is considered to result from neutrophil dysfunction and dysregulation of the inflammatory response. Cases of drug-induced PG are rare and attributed to certain drugs. Clozapine is an antipsychotic medication for the treatment of refractory schizophrenia. It is suggested that clozapine alters plasma TNF-α levels and thus can modulate the inflammatory response. To date, a variety of adverse skin reactions (Stevens- Johnson syndrome, DRESS syndrome etc) have been previously described in the literature. However, to the best of our knowledge, this is the first case which strongly indicates the likely association between clozapine and drug-induced PG. Disclosure of Interest None Declared

Introduction Ketamine, originally an anesthetic, has emerged as a potent tool in the fight against treatment-resistant depression and suicide. Clinical trials have demonstrated its ability to induce remission of severe depressive symptoms, with effects that can extend over several weeks.Furthermore, research highlights Ketamine’s potential to rapidly reduce suicidal ideation. This suggests Ketamine’s role as an intervention in suicide prevention, especially when conventional treatments prove ineffective. While isolated cases report severe respiratory depression, primarily when combined with other medications, most incidents involve temporary apneic episodes following high-dose intravenous administration. Understanding Ketamine’s safety profile is vital for its clinical optimization and ensuring patient well-being during use Objectives This presentation serves to describe, and evaluate our clinic’s safety protocol implemented for intravenous (IV) Ketamine infusions at the General Hospital of Corfu. Our primary goal is to rigorously assess the safety and tolerability of IV Ketamine in a clinical setting Methods Patients must meet stringent criteria: - Exclude those over 70. - MMSE score above 25. - Controlled blood pressure. - No cardiac insufficiency, myocardial ischemia, or high intraocular/intracranial pressure. - Absence of thyrotoxicosis, psychosis, or seizures. Pre-infusion comprehensive evaluation: - Includes ECG, blood biochemistry studies, and frequent blood pressure checks. - Requires a 2-hour fast. Ketamine infusion: - IV Ketamine administered at 0.5mg/kg in 100ml N/S. - Continuous monitoring of oxygen saturation (PO2) and cardiac rhythm. - Blood pressure checks every 15 minutes. Treatment typically involves 7 sessions over a span of a month, with an initial test dose of 0.25 mg/kg. Results Ketamine infusions were administered to a total of 208 patients. The majority of participants experienced a slight increase in blood pressure, while there were no significant changes in cardiac rhythm. Additionally, almost all patients reported experiencing dizziness or headaches during the infusion. Notably, nearly half of the patients reported an alteration in taste perception as a side effect. It’s important to highlight that all observed side effects, spontaneously resolved within an hour after the conclusion of the infusion. However, in a small subset of cases (six instances), the side effects were severe enough to necessitate the premature termination of the ketamine infusion Conclusions Although ketamine demonstrates a favorable safety profile with minimal major side effects when administered following our established safety protocol. However, we want to underscore the critical importance of vigilant patient monitoring during ketamine administration and the prompt addressing of any adverse effects. This proactive approach is paramount to ensure the safety and overall well-being of patients receiving ketamine treatment Disclosure of Interest None Declared

Introduction Hyperprolactinemia (HPL) is a condition associated with disturbing consequences. Antipsychotic medications are one of the main causes of nontumoral hyperprolactinemia. Prolactin release in the hypothalamic tuberoinfundibular tract is increased through dopaminergic inhibition, which occurs more frequently with high- potency typical antipsychotics (40%–90%). Less commonly than typical antipsychotics, atypical antipsychotics can also result in hyperprolactinemia. In the presence of symptoms, clinicians frequently struggle with the decision of whether to stop using the suspected offending agent, lower the dosage, switch to another medication, or even add a full or partial dopamine agonist to the patient's current treatment. The issue is exacerbated by the fact that finding a suitable agent for each patient is sometimes a challenging task. Objectives Due to the partial D2 receptor agonistic activity of aripiprazole, there is enough dopaminergic tone to continue the inhibition of prolactin release. Aripiprazole has been recommended in literature either as an adjunctive treatment in low doses or as a switch in therapy. Methods In the Psychiatric clinic of the General Hospital of Corfu, a low-dose (5mg/day) of aripiprazole is being used as adjunctive therapy in patients with antipsychotic-induced hyperprolactinemia. More specifically in total 42 subjects, 19 male and 22 female, with a mean prolactin level of 862ng/ml, were introduced to the prior therapy. We whereupon conducted prolactin measurements to evaluate the response at the first, the third, and the sixth month of treatment. Results Of the 42 subjects, 38 responded with an average reduction of prolactin to the level of 530ng/ml (mean reduction 38,5%). Conclusions Having noticed the beneficial effect of low-dose Aripiprazole in patients with antipsychotic-induced hyperprolactinemia, we consider it appropriate that the literature recommendations concerning this additional use of aripiprazole should not be overlooked in clinical practice. Disclosure of Interest None Declared

Introduction An undeniably significant amount of psychotropic medication can evidently affect the corrected QT (QTc) interval, which puts patients’ lives at risk. More specifically, certain anti-psychotic medication can increase the risk of QTc prolongation and by extension the risk of a potentially fatal arrhythmia or sudden cardiac death. Objectives Electrocardiograms (ECG) were contacted in one hundred and four (104) chronic patients, with psychosis, through out their hospitalization in several enclosed psychiatric facilities in Corfu. Almost the entirety of the patients along side their anti-psychotic medication were also taking various other medication for their individual pathological issues. We observed any changes that might have occurred on the ECG in comparison with each patient’s medication and it’s potential effect on the QTc. Methods The measurements of the QT interval were made manually in lead V5 and the mathematical conversion was contacted using the Hodges correction formula. Results At least one ECG (n = 104) was performed. Among them 29,8% (n=31) had ECG abnormalities, including 13,5% (n=13) with a prolonged Qtc (481.2 ± 26,8 ms). Covariates significantly associated with the QTc were gender (+17.2 ms if female, p < 0.0001) and age (+0.4 ms/year, p = 0.0001). Conclusions The QTc prolongation that was evident in a notable number of patients, emphasizes the importance of QTc monitoring in patients who are taking anti-psychotic medication. QTc prolongation risk factors should be assessed before the administration or prescription of any anti-psychotic medication. Disclosure of Interest None Declared

Copper-free “click” chemistry on appropriately modified surfaces and photolithography were explored for site-directed immobilization of biomolecules. The surfaces were modified either with self-assembled monolayers of silanes or an epoxy resin and then used as they were or further modified through adsorption of rabbit gamma-globulins to increase their reactive amine-content. All surfaces were then reacted with a succinimidyl ester cyclooctyne derivative and the efficiency of each modification approach was determined through click reaction with an azide derivative of fluorescein. It was found that the highest fluorescence signal was provided by the surface that had been modified with the epoxy resin and then coated with rabbit gamma-globulins. Surfaces prepared following the different modification procedures have been analyzed with ToF-SIMS to gain insight into the chemical changes of the surfaces after each step of the modification procedure. Analysis of intensities of characteristic ions signals confirmed the successful outcome of click reaction following the proposed surface modification approach. In addition, the ability to define through photolithography areas for site-directed immobilization of biomolecules onto surfaces modified with the succinimidyl ester cyclooctyne derivative was demonstrated through the creation of two molecules patterns.

Two gallium porphyrins, a tetraphenyl GaCl porphyrin, termed as (TPP)GaCl, and an octaethylporphyrin GaCl porphyrin, termed as (OEP)GaCl, were synthesized to use as an electron cascade in ternary organic bulk heterojunction films. A perfect matching of both gallium porphyrins’ energy levels with that of poly(3-hexylthiophene-2,5-diyl) (P3HT) or poly[N-9′-heptadecanyl-2,7-carbazole-alt-5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzothiadiazole)] (PCDTBT) polymer donor and the 6,6-phenyl C71 butyric acid methyl ester (PCBM) fullerene acceptor, forming an efficient cascade system that could facilitate electron transfer between donor and acceptor, was demonstrated. Therefore, ternary organic solar cells (OSCs) using the two porphyrins in various concentrations were fabricated where a performance enhancement was obtained. In particular, (TPP)GaCl-based ternary OSCs of low concentration (1:0.05 vv%) exhibited a ~17% increase in the power conversion efficiency (PCE) compared with the binary device due to improved exciton dissociation, electron transport and reduced recombination. On the other hand, ternary OSCs with a high concentration of (TPP)GaCl (1:0.1 vv%) and (OEP)GaCl (1:0.05 and 1:0.1 vv%) showed the poorest efficiencies due to very rough nanomorphology and suppressed crystallinity of ternary films when the GaCl porphyrin was introduced to the blend, as revealed from X-ray diffraction (XRD) and atomic force microscopy (AFM). The best performing devices also exhibited improved photostability when exposed to sunlight illumination for a period of 8 h than the binary OSCs, attributed to the suppressed photodegradation of the ternary (TPP)GaCl 1:0.05-based photoactive film.

Introduction Common side effects are agranulocytosis and myocardiopathy. There are reports of myocardite related to m-rna vaccine for covid-19 (Pfizer-Bionteck), while the interactions with clozapine has not been yet studied. Objectives The object of the study is to explore the safety of COVID-19 vaccination at patients treated with clozapine. Methods We report a group of 27 patients from the psychiatric rehabilitation unit of the General Hospital of Corfu who were treated with clozapine and another group of 27 patients on different antipsychotic. Levels of clozapine were measured before the 1st vaccination and one month after the individuals were fully vaccinated, as well their COVID antibodies. For myocarditis detection we used CRP >1mg/dl and quadruplication of the troponin of reference. Results No significant difference has been observed among the 2 groups in relation to antibody production, No difference has been detected between clozapine and nor-clozapine serum levels before and after vaccination. While there was no case of myocarditis or vein embolism noticed. Conclusions It seems that patients treated with clozapine develop immune response to COVID-19 as individuals in any other anti-psychotic. No major side effects were reported at the two groups leading as to the conclusion that treatment with clozapine sould not be an obstacle for COVID-19 vaccination. Thus to the small number of patients in this study further research is needed. Disclosure No significant relationships.

Solar cells based on metal halide perovskite and polymer donor:nonfullerene acceptor blend absorbers have recently witnessed a significant rise in their photovoltaic performance. However, they still suffer from some instability issues originating from the inferior interface quality and poor nanomorphology of the absorber layer. In this work, a series of functionalized boron‐dipyrromethene, BODIPY, molecules are introduced as ultrathin interlayers at the absorber/electron transport layer interface. This study indicates that BODIPY compounds with a high molecular dipole moment can enhance the device performance mainly due to better interface energy level alignment. They also induce passivation of defect traps and improvement in the charge transport properties of the absorber layer coated on top of them. Among the various compounds used, amino‐functionalized BODIPY, owing to the synergetic effect of the abovementioned factors, enables the highest power conversion efficiency in organic (15.69%) as well as in perovskite solar cells (20.12%). Amino‐functionalized BODIPY also demonstrates an enhanced stability under continuous illumination (in nitrogen) without and with heating (at 65 °C) for 1000 h. These results pave the way for the implementation of molecules with tailor‐made functionalities in high efficiency and stable solution‐based photovoltaic devices of the future.

Introduction Successful stabilization of patients with mental disorders requires most of the times the use of more than one antipsychotic medications with increase prevalence of clozapine in refractory cases. Constipation consists one of the most debilitating side effect of the therapy, which gradually progresses to a chronic state of bowel movement dysfunction, with recurrent episode of paralytic ileus of various severity. Objectives We describe the case of a middle age male treated with clozapine for refractory mental disorder, who developed ileus and subsequent bowel dysfunction not amenable to laxatives. Methods The acute episode have been treated conservatively with nasogastric decompression, intravenous replacement of fluids and electrolytes, antibiotics chemoprophylaxis and low molecular weight heparin. His overall physical status was unremarkable for obesity, diabetes, hypertension, allergies, previous operations and a former endoscopic evaluation conducted in the recent past, which had ruled out malignant neoplastic disease. Results A course of per os prucalopride have been instituted, which showed preliminary promising results in restoring proper bowel movements, without any serious side effect and without the need to discontinue his course with antipsychotics. Prucalopride is a 5 HT4 agonist which selectively binds to the receptors of the intestine, resulting in muscular contractions as well as clorium secretion from the mucosa promoting an osmotic defecation.The substance has been extensively use in the treatment of irritable bowel disease of the chronic constipation type. Conclusions We suggest the more systematic use of this agent in this group of patients after proper endoscopic evaluation and restoration of all secondary causes of constipation. Disclosure No significant relationships.

Earth-abundant transition metal oxides deposited at room temperature with low-cost methods suitable for large area manufacturing can offer advances in many fields of energy related devices. Here we report the room-temperature deposition of a fluorine-doped tantalum pentoxide using a home-made, low-cost hot-wire deposition system. This novel tantalum oxyfluoride material is super hydrophobic, ultra-transparent within the visible spectrum, and possesses adequate conductivity and suitable valence band and conduction band extrema for acting as efficient hole extraction and electron blocking layer in organic solar cells with the forward architecture. By inserting this material in the form of nanoparticles deposited on top of the commonly used as hole transport layer poly(3,4-ethylenedioxythiophene) polystyrene sulfonate, higher efficiencies compared to the reference cells without the nanoparticles were demonstrated in solar cells based on blends of polymer donors with either a fullerene (where maximum achieved efficiency was improved from 6.07% to 7.90%) or a non-fullerene acceptor (reaching values of 13.48% compared to 11.32% of the reference cell). Moreover, significant improvement in device stability was achievd in unencapsulated devices continuously exposed in a humid environment for 500 h. This work demonstrates the unambiguous potential of well-designed metal oxide materials as charge transport and blocking interlayers and protective buffers in organic solar cells and beyond.

Introduction Patients with schizophrenia usually demonstrate low compliance to medication. This could be a component of the disorder or a fact that they are not being properly cared. Objectives To prevent this in, we tried to treat these patients with long term action antidiabetic agents, in order to achieve better compliance. Methods HbA1C measurements of patients suffering from schizophrenia and at the same time receiving oral antidiabetic treatment were conducted. 62 patients were found that fell under the criteria of non regulated type 2 diabetes and at the same time presented less than 70% complied with their antidiabetic pharmaceutical treatment. We modified the antidiabetic treatment of these patients, with the introduction of dulaglutide. Results Without intervening with their nutritional habits there was a decline in HbA1C measurements from the average rate of 9,4% to the average rate of 7,6%, as well as an average 6,31% reduction of their body weight. Conclusions Due to the improvement of the general medical condition of these patients, the answer to the question whether these patients should be treated with a long term antidiabetic medicines, is positive. The arrival of new long term action antidiabetic medicines in the near future, promises to improve the life quality of schizophrenic patients furthermor. Disclosure No significant relationships.

High-performance perovskite light-emitting diodes (PeLEDs) require a high quality perovskite emitter and appropriate charge transport layers to facilitate charge injection and transport within the device. Solution-processed n-type metal oxides represent a judicious choice for the electron transport layer (ETL); however, they do not always present surface properties and energetics compatible with the perovskite emitter. Moreover, the emitter itself exhibits poor nanomorphology and defect traps that compromise the device performance. Here, we modulate the surface properties and interface energetics between the tin oxide (SnO 2 ) ETL with the perovskite emitter by using an amino functionalized difluoro{2-[1-(3,5-dimethyl-2 H -pyrrol-2-ylidene- N )ethyl]-3,5-dimethyl-1 H -pyrrolato- N }boron compound and passivate the defects present in the perovskite matrix with carbon-polymer core–shell quantum dots inserted into the perovskite precursor. Both these approaches synergistically improve the perovskite layer nanomorphology and enhance the radiative recombination. These properties resulted in the fabrication of near-infrared PeLEDs based on formamidinium lead iodide (FAPbI 3 ) with a high radiance of 92 W sr −1 m −2 , an external quantum efficiency (EQE) of 14%, reduced efficiency roll-off and prolonged lifetime. In particular, the modified device retained 80% of the initial EQE (T 80 ) for 33 h compared to 6 h of the reference cell.