Purpose: To investigate the feasibility and impact of dynamic contrast-enhanced-magnetic resonance imaging (DCE-MRI) on tumor characterization and response to radiochemotherapy (RCT) in patients with esophageal cancer.Materials and Methods: A total of 48 patients underwent DCE-MRI to assess tumor microcirculation based on a two-compartment model function. Effects of RCT on kinetic parameters were studied in 12 patients with squamous cell carcinoma.Results: Tumor microcirculation differs with respect to histological subtype: squamous cell carcinomas showed lower values of amplitude A (leakage space, P = 0.015),and higher contrast agent exchange rates (k(21), P = 0.225) compared with adenocarcinomas. RCT led to a significant decrease of the contrast agent exchange rate (P = 0.005), while amplitude,A increased moderately after therapy (P = 0.136).Conclusion: DCE-MRI is feasible in patients with esophageal cancer, reveals therapeutic effects, and may thus be useful in therapy management and monitoring.

This paper summarizes the initial development of a very small-scale rotorcraft that flies on its own power and carries sensors for atmospheric research or planetary exploration. Initial devices are electrically powered, ranging in size from 2 to 15 cm, and have involved challenges in aerodynamics, control, and manufacturing. Many interesting scaling issues arise as one shrinks a flight vehicle down to this size. Certain scaling attributes are favorable, such as the increased strength and rigidity of structures at small scales, while others, such as aerodynamics, represent significant challenges. This paper summarizes the aerodynamic design of the rotor system, and approaches to fabrication, control, and power systems. Results of prototype tests suggest that the concept can be successfully produced and that the design methodology is appropriate, despite the insect-like scale of the rotors. Results of recent experiments with a larger version of this concept intended to fly on Mars are also described.

Presented at the American Helicopter Society Vertical Lift Aircraft Design Conference, San Francisco, CA. Copyright © 2000 by the American Helicopter Society, International. All rights reserved. Abstract This paper describes the development of a centimeterscale rotorcraft for use as an atmospheric sensor platform. The aerodynamic design of the rotor system is highlighted, while approaches to fabrication, control, and power systems are summarized. 2D Navier-Stokes analysis and design of the rotor sections was combined with 3D nonlinear optimization of the rotors. Results of prototype tests suggest that the concept can be successfully produced and that design methodology is appropriate, despite the insect-like scale of the rotors.

Skoda is going through a tremendous transformation process. In joint venture with VW Skoda is developing into a modern and competitive car company. By introduction of new technologies, new kinds of work organisation and modern personnel management the esssential steps to the “new Skoda” have been taken. Efficient project management and fast know-how transfer out of the VW group are accelerating the speed of the process of change. By example of core projects on creating a Skoda management culture it is shown how the key processes in the company are initiated, controlled and stabilized.

Chemie Ingenieur TechnikVolume 61, Issue 4 p. 328-329 Wissenschaftliche Forschungsarbeit Erhöhung der Wirtschaftlichkeit von Blockheizkraftwerk-Anlagen zur Faulgasnutzung in Kläranlagen† Dr. Eberhard Böhm, Dr. Eberhard Böhm Fraunhofer-Institut für Systemtechnik und Innovationsforschung (ISI), Breslauer Str. 48, 7500 Karlsruhe 1Search for more papers by this authorDipl.-Ing. Dominik Toussaint, Dipl.-Ing. Dominik Toussaint Fraunhofer-Institut für Systemtechnik und Innovationsforschung (ISI), Breslauer Str. 48, 7500 Karlsruhe 1Search for more papers by this authorProf. Dr. Peter Kunz, Prof. Dr. Peter Kunz FHT Mannheim, Speyerer Str. 4, 6800 Mannheim 1Search for more papers by this author Dr. Eberhard Böhm, Dr. Eberhard Böhm Fraunhofer-Institut für Systemtechnik und Innovationsforschung (ISI), Breslauer Str. 48, 7500 Karlsruhe 1Search for more papers by this authorDipl.-Ing. Dominik Toussaint, Dipl.-Ing. Dominik Toussaint Fraunhofer-Institut für Systemtechnik und Innovationsforschung (ISI), Breslauer Str. 48, 7500 Karlsruhe 1Search for more papers by this authorProf. Dr. Peter Kunz, Prof. Dr. Peter Kunz FHT Mannheim, Speyerer Str. 4, 6800 Mannheim 1Search for more papers by this author First published: 28 April 1989 https://doi.org/10.1002/cite.330610415 † Vortrag von D. Toussaint auf dem Jahrestreffen der Verfahrens-Ingenieure, 21. bis 23. Sept. 1988 in Hannover. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. Volume61, Issue428 April 1989Pages 328-329 RelatedInformation

This paper describes the development of a centimeter- scale rotorcraft for use as an atmospheric sensor platform. The aerodynamic design of the rotor system is highlighted, while approaches to fabrication, control, and power systems are summarized. 2D Navier-Stokes analysis and design of the rotor sections was combined with 3D nonlinear optimization of the rotors. Results of prototype tests suggest that the concept can be successfully produced and that design methodology is appropriate, despite the insect-like scale of the rotors.