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1Toxicity and Chemistry of 11-Desmethoxyreserpine (Raunormine1) (3,4,5-Trimethoxybenzoic Acid Ester of Methyl-11-desmethoxyreserpate), an Alkaloid from Rauwolfia canescens I

Jos. W. E. Harrisson,Elias W. Packman,Erick Smith,Norman Hosansky,Ralph Salkin

Rauwolfia canescens yields another alkaloid which possesses sedative and strong hypotensive activity. This newly isolated ester alkaloid has been termed 11- desmethoxyreserpine. Unlike reserpine, this alkaloid does not yield reserpic acid upon hydrolysis. The acid resulting as a hydrolysis product of 11-desmeth- oxyreserpine has been termed raunormic acid, whose physical properties differ markedly from those of reserpic acid. Acute oral, intraperitoneal, and chronic oral toxicity studies indicate that 11-desmethoxyreserpine exhibits in the test animal a favorable therapeutic index, thus assuring relative safety, warranting further pharmacologic and clinical studies.

2006Journal of the American Pharmaceutical Association (Scientific ed.)（2006）引用：10

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2Leaf Alkaloids of Rauwolfia nitida

Ralph Salkin,Norman Hosansky,Robert Jaret

The leaves of Rauwolfia nitida Jacq. have yielded two new indole alkaloids, raunitidine, an 11-methoxy-δ-yohimbine, and rauniticine, an isomer of ajmalicine.

1961Journal of Pharmaceutical Sciences（1961）引用：16

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3Toxicity and Chemistry of 11-Desmethoxyreserpine(Raunormine1) (3,4,5-Trimethoxybenzoic Acid Esterof Methyl-ll-desmethoxyreserpate), anAlkaloid from Rauwolfia canescens1Raunormine is trademark of S. B. Penick & Co. for their 11-desmethoryreserpine which was used in this study.

Jos. W.E. Harrisson,Elias W. Packman,Erick Smith,Norman Hosansky,Ralph Salkin

1955Journal of the American Pharmaceutical Association (Scientific ed.)引用：9

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4Large-Size Laboratory Soxhlet Extractor

R SALKIN, IA KAYE

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLarge-Size Laboratory Soxhlet ExtractorRalph Salkin and Irving Allan KayeCite this: Ind. Eng. Chem. Anal. Ed. 1946, 18, 3, 215–216Publication Date (Print):March 1, 1946Publication History Published online1 May 2002Published inissue 1 March 1946https://pubs.acs.org/doi/10.1021/i560151a021https://doi.org/10.1021/i560151a021research-articleACS PublicationsRequest reuse permissionsArticle Views91Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts

1946Industrial & Engineering Chemistry Analytical Edition引用：1

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