75 Biogenic amine transporter 102 Blue light 75 Body composition, pigs 53 Bone mineral content 198 Brain development 119 -lesion 299 -stem auditon-evoked response 31 Calcium 37 Carotid sinus nerve 251 Catecholamine kinetics 102 CD30 cytokine receptor 69 CD30/CD30L system 69 Central nervous system 137 Cerebral blood flow 385 -oxygen delivery 385 -palsy 83 Cerebrovascular circulation 22 Chcmosensory denervation 251 Chlorpromazine 345 Chorioamnionitis 46 Cocaine
Testicular immunoreactive arginine vasopressin (irAVP) has been shown to inhibit testosterone production by the Leydig cell in vitro. We studied pre- and postpubertal rats and the results are in agreement with the notion that such inhibition might occur in vivo and, therefore, could have physiological significance. Testicular irAVP and serum testosterone levels were measured in 14-, 21-, 28-, 35-, 42-, and 70-day-old rats. The testicular irAVP concentration was lowest in early prepubertal rats, increased significantly to the highest level at 35 days, then decreased at 42 days, and plateaued at 70 days of age. A pubertal increase in serum testosterone was observed at 42 days when AVP was decreasing. Thus, an inverse relationship was observed at the onset of pubertal maturation. These parameters were also measured in 3 groups of rats 1 week after hemicastration which was performed at the ages of 28, 35 and 70 days. In the 28-day-old rats there was a significant decrease in irAVP 1 week later, in contrast to the intact animal, whereas hemicastration performed at 35 and 70 days of age had no impact on irAVP. Our data suggest that the role of AVP may be physiologically relevant during the peripubertal period of testicular maturation in the rat.