Gallium 67 (67Ga) lung scanning was performed in 100 consecutive cases in which because of the history, clinical data, or abnormal radiological findings, a bronchial carcinoma was suspected. This study allows the conclusion that a negative as well as a positive scan is an important element in the diagnosis of some cases of bronchial carcinoma. The method is most helpful in the preoperative diagnosis of circumscribed peripheral shadows and in the assessment of suspected hilar enlargement; it may even visualise hidden malignant tumours. Gallium 67 scanning is also valuable in the assessment of hilar and mediastinal involvement in the presence of a proven primary lung tumour. This study supports the view that in the presence of a negative mediastinal scan the patient may be spared mediastinoscopy and be referred directly for operation.

The effect of beta-adrenergic blockade on blood pressure variation was studied in ten patients with moderate hypertension. Supine systolic and diastolic blood pressures were measured every 5 min during six hours sessions, using an ultrasonic method. Systolic and diastolic variation in each six hour session was defined as the standard deviation of the mean of systolic and diastolic readings made in that period. After 3 weeks of single-blind placebo, a 12 week double-blind randomized crossover study was initiated with placebo (6 weeks) and atenolol (100 mg b. i. d. for 3 weeks and 200 mg b. i. d. for 3 weeks). Systolic and diastolic blood pressure and heart rate decreased significantly (p<0.01) during atenolol treatment. Diastolic variation did not change significantly, whereas systolic variation decreased slightly but significantly (p<0.05) when expressed in absolute values, but not when expressed as a percentage of systolic blood pressure. It is concluded that beta-adrenergic blockade decreases blood pressure and heart rate without causing significant changes in spontaneous systolic or diastolic variation

Belgians have been gradually shifting from a low ratio of polyunsaturated/saturated fat in their food to a higher one with lower total fat and cholesterol. This has occurred predominantly in the north, where the most obvious change is a decrease in butter consumption and an increase in margarine consumption. The northerners have a four to five times smaller intake of butter than the southerners and nearly double the intake of margarine. Evidence gathered over the past ten years reveals in the north a decreasing serum-cholesterol and in the south a significantly higher serum-cholesterol, associated with higher coronary morbidity and mortality. Life expectancy of males in the north is 2.4 years higher at birth and 2.2 years higher at the age of 30. It is concluded that the food habits of a population can be changed, with great benefit.

AbstractDas durch Kochen von Ferrocen‐l. ,V‐dicarbonsäurediamid mit Phosphoroxychlorid in 81 ,4%iger Ausbeute dargestellte Dicyanferrocen (I) wurde mit Na‐azid in THF in Gegenwart von Al‐chlorid zu dem Bis‐tetrazolylferrocen (II) (Ausbeute fast quantitativ) umgesetzt.

The synthesis of some phosphinic acid ureides und -thioureides is described. The results of the synthesis of phosphonic acid diureides are discussed.

AbstractFerrocencarbonylhydrazide wurden durch Umsetzung von Ferrocencarbonsäureestern order ‐chloriden mit Hydrazin oder Säurehydraziden hergestellt und durch Cyclodehydratisierung in die entsprechenden 1,3,4‐Oxadiazole übergeführt. Ferrocenyl‐1,3,4‐Oxadiazole konnten auch durch direkte Synthese aus Ferrocencarbonsäurechloriden und substituierten Tetrazolen gewonnen werden. Nach analogen Methoden wurden Poly‐ferrocenylen‐hydrazide und Poly‐ferrocenylen‐1,3,4‐oxadiazole hergestellt. Die thermische Beständigkeit der Poly‐ferrocenylen‐1,3,4‐oxadiazole wurde untersucht.