目的:观察脑心通胶囊联用瑞舒伐他汀钙片对急性缺血性脑卒中(AIS)患者炎症及氧化应激水平的影响.方法:AIS患者112例随机分两组.对照组(55例)给予AIS常规治疗联合瑞舒伐他汀钙片,研究组(57例)在对照组治疗基础上加用脑心通胶囊.治疗3周后,比较两组患者治疗前后血清三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、白介素-6(IL-6)、肿瘤坏死因子α(TNF-α)、C反应蛋白(CRP)、氧化低密度脂蛋白(OX-LDL)、异前列腺素F2α(8-isoPGF2α)、超氧化物歧化酶(SOD)及美国国立卫生研究院卒中量表(NIHSS)评分变化,评价两组疗效及安全性.结果:治疗后,两组患者血脂指标(TG、TC、LDL-C、HDL-C)、炎症指标(IL-6、TNF-α、CRP)和NIHSS评分均较前明显改善(P＜0.01),且研究组各项指标均优于对照组(P＜0.05或P＜0.01).对照组治疗后8-iso-PGF2α明显下降(P＜0.01),SOD明显上升(P＜0.05),研究组OX-LDL、8-iso-PGF2α明显下降(P＜0.01),SOD明显升高(P＜0.01);且研究组OX-LDL及8-iso-PGF2α明显低于对照组(P＜0.05或P＜0.01).两组总有效率差异无统计学意义(P＞0.05),且研究期间均未见不良反应发生.结论:在西医治疗基础上加用脑心通胶囊具有加强降血脂、抗炎、抗氧化应激作用,临床疗效优于单用西医综合治疗方案.

目的 观察100g/L氯化钠溶液在婴幼儿低渗尿液有形成分分析中的应用.方法 收集2016年6月至2017年12月该院门诊和住院婴幼儿低渗尿液标本104份,每份标本留取两管,一管为对照管,另一管加入100g/L氯化钠溶液为测试管,分别行UF-500i尿沉渣分析和人工镜检.结果 对照管尿沉渣分析仪检测RBC、WBC及上皮细胞(EC)的灵敏度分别为5/15、8/19及6/15,特异度分别为98.9％、98.8％、98.9％.测试管尿沉渣分析中检测RBC、WBC及EC的灵敏度分别为14/17、17/19及15/17,特异度分别为98.9％、96.5％、97.7％.结论 在婴幼儿低渗尿液中加入100g/L氯化钠溶液进行有形成分分析时能提高RBC、WBC及EC的敏感性,能快速地为临床提供更准确的结果.

目的 分析医联体模式下缙云地区老年人常规生化指标,初步评估缙云县老年村民的健康状态,为该地区在县乡级医联体背景下组建慢性病健康管理团队提供数据支持.方法 2016年6—11月缙云县17家乡镇自愿享受浙江省新型合作医疗免费健康体检的老年村民共31518人.比较不同性别、不同年龄段老年人各项生化指标间的差异.结果 男性BUN、Cr的异常率高于女性,而ALT、AST、葡萄糖(GLU)、TC、TG异常率明显低于女性;ALT、AST、TC、TG异常率随着年龄增长而下降;GLU、BUN、Cr异常率随着年龄增长而上升.结论 缙云地区老年人的生化指标随性别、年龄的不同有明显差异,可根据老年村民生化指标的特点组建医联体内有针对性的慢性病健康管理团队,实现"健康老龄化".

目的 了解本地区近三年就诊患者阴道分泌物中病原菌感染与生理年龄、季节、清洁度之间的关系.方法 对29,917例阴道分泌物进行白带常规检查和细菌性阴道病联合测定试剂盒检测,并对检验结果进行回顾性分析.结果 29,917例阴道分泌物中霉菌检出率以21岁-30岁组最高,而滴虫和加德纳菌检出率以41岁-50岁组最高;霉菌的感染率在春季最低,而滴虫和加德纳菌在4个季节之间,没有显著变化;随着清洁度增高,病原菌检出率也依次升高;然而在清洁度正常的情况下,也有一定的条件致病菌检出率.结论 病原菌的感染率与患者生理年龄、季节及清洁度都有关联.

Objective To analyze and study the relationship of fasting plasma glucose (FPG) indicators with age, gender and community in Jinyun, in order to provide data support for the establishing of blood sugar health management team under the background of county and township medical alliance. Methods With township hospitals as centers, FPG was sampled from villagers for centralized testing and software analysis. Results The abnormal rates of the FPG in male villagers were higher than that in female villagers in the young and middle-aged group (P ＜ 0. 01), while the abnormal rates of the FPG in male villagers were lower than that in female villagers in elder group (P ＜ 0. 01). With the increase of age, the abnormal rate of FPG in male and female increased significantly (P ＜ 0. 01). Based on the cluster analysis of the abnormal FPG rates in the 17 towns of Jinyun, the abnormal rates of young and middle-age group in Dayang, Qili and Qianlu were higher than that in other towns. In the elderly group, the abnormal rate was the highest in Dayang, followed by Dongfang and Fangxi. Conclusion The elderly female in Jinyun are the key prevention and treatment population. Different age groups have their own high incidence of abnormal blood sugar, and should be treated differently.