Systemic administration of 8-methoxypsoralen (8-MOP) is associated with considerable acute side effects such as nausea, vomiting, liver toxicity and eye sensitisation making it necessary for the patient to wear permanently UV protective goggles to prevent cataractogenesis [2, 3, 5, 7, 8]. Furthermore, systemic administration of 8-MOP leads to photosensitization of the entire skin, including the face, for at least 6–12 h.

Journal of Clinical ApheresisVolume 12, Issue 3 p. 154-155 Short Communication Photopheresis—A possible treatment of multiple sclerosis? Report of two cases D. Poehlau, Corresponding Author D. Poehlau Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanyDepartment of Neurology, St. Josef Hospital Bochum, Ruhr-University Bochum, Gudrunstr. 56, D-44791 Bochum, GermanySearch for more papers by this authorM. Rieks, M. Rieks Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorT. Postert, T. Postert Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorR. Westerhausen, R. Westerhausen Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorS. Busch, S. Busch Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorK. Hoffmann, K. Hoffmann Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorP. Altmeyer, P. Altmeyer Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorH. Przuntek, H. Przuntek Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this author D. Poehlau, Corresponding Author D. Poehlau Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanyDepartment of Neurology, St. Josef Hospital Bochum, Ruhr-University Bochum, Gudrunstr. 56, D-44791 Bochum, GermanySearch for more papers by this authorM. Rieks, M. Rieks Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorT. Postert, T. Postert Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorR. Westerhausen, R. Westerhausen Department of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorS. Busch, S. Busch Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorK. Hoffmann, K. Hoffmann Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorP. Altmeyer, P. Altmeyer Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this authorH. Przuntek, H. Przuntek Department of Dermatology, St. Josef Hospital, Ruhr-University Bochum, Bochum, GermanySearch for more papers by this author First published: 07 December 1998 https://doi.org/10.1002/(SICI)1098-1101(1997)12:3<154::AID-JCA9>3.0.CO;2-9Citations: 14AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article.Citing Literature Volume12, Issue31997Pages 154-155 RelatedInformation

In patients with progressive systemic sclerosis (PSS) suffering from chronic dyspepsia the stomach may be affected by this disease. The objective of this study was to investigate both antral myoelectrical activity and gastric emptying in PSS patients.Electrogastrography (EGG) was performed in 17 PSS patients (16 female, one male, median age 58 years, range 32-74 years) with chronic dyspepsia. After an overnight fast during one hour in the fasting and one hour in the fed state after ingestion of a liquid-solid test meal (370 kcal; liquid phase labeled with 0,5 mCi Tc-99m-colloid) antral electrical activity was measured by one pair of electrodes sonographically placed on the skin overlying the gastric antrum. Several EGG parameters including dominant frequency (DF), percentages of DF in the normal range (2-4 cycles per minute [cpm]), bradygastria (< 2 cpm) and tachygastria (4-10 cpm), dominant frequency instability coefficient (DFIC), and postprandial to preprandial power ratio (PR) were calculated. The data were correlated to results obtained in 20 age- and gender-matched healthy subjects. In addition, the data were compared to gastric retention of the radionuclide at 60 min measured by simultaneous scintigraphy.The PSS patients did not reveal electrical disturbances. They even exhibited a significant postprandial decrease in DFIC, bradygastria, and tachygastria (ns) compared to healthy subjects. Over 50% of the PSS patients showed a delayed gastric emptying. However, EGG did not correlate to radioscintigraphy significantly.Our results reflect an absent relationship between antral myoelectrical activity in EGG and gastric emptying. Therefore, electrogastrography is unsuitable to assess gastric involvement in PSS.