Reactions of 2-amino-4-phenylthiazole with aromatic aldehydes gave the corresponding Schiff bases which were reduced with sodium tetrahydridoborate to amines. Reactions of the Schiff bases with 2-methyloxirane, 2-chloromethyloxirane, and 2-phenoxymethyloxirane led to the formation of 2,5-disubstituted 3-(4-phenylthiazol-2-yl)oxazolidines.

Reactions of 2-amino-4-phenyl-1,3-thiazole with aromatic aldehydes, phenyl isocyanate, and carboxylic acid chlorides were studied.

Reactions of 2-amino-4-arylthiazoles with aromatic aldehydes afforded the corresponding Schiff bases. Complex formation of the latter with nickel, zinc, cobalt, manganese, and copper salts was studied.