ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCellulose Digestibility, Birefringence of Plant Fibrous Cellulose and Microcrystalline Cellulose in Human Stools Freezer-Stored Immediately after EvacuationT. W. Tusing, O. E. Paynter, and O. A. BattistaCite this: J. Agric. Food Chem. 1964, 12, 3, 284–287Publication Date (Print):May 1, 1964Publication History Published online1 May 2002Published inissue 1 May 1964https://doi.org/10.1021/jf60133a029RIGHTS & PERMISSIONSArticle Views152Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (3 MB) Get e-Alerts Get e-Alerts
The acute and chronic toxicity of sodium lauryl glyceryl ether sulfonate and sodium lauryl trioxyethylene sulfate have been studied in rats, and skin tumorigenicity has been investigated in mice. LD50 values determined by oral administration to rats were 1.82 g/kg for both compounds. Rats received the surface-active agents at levels of 0.1% and 0.5% in the diet for two years, with some animals sacrificed for examination at the end of one year. No adverse effects were observed in the experimental animals with respect to survival, growth, reproduction, food consumption, hematologic values, blood chemistry, or urine analyses. Microscopic evaluation of tissues revealed no pathogenic changes resulting from ingestion of the test materials. Scattered differences were found in organ: body weight ratios. No effects of the surfactants were observed in first or second generation offspring of the original animals. Twice-weekly application, for 105 weeks, of 5% aqueous solutions of sodium lauryl glyceryl ether sulfonate and sodium lauryl trioxyethylene sulfate to the skin of Swiss female mice did not lead to the development of skin tumors in any of the animals. Based on the results of these investigations there is no evidence that exposure to these two surfactants poses a toxic hazard to humans.
A two-year feeding study has been completed in which rats received 0.1% (1000 ppm) and 0.5% (5000 ppm) of alkylbenzenesulfonate in the diet.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHerbicide Toxicology, Toxicology of Dalapon Sodium (2,2-Dichloropropionic Acid, Sodium Salt)O. E. Paynter, T. W. Tusing, D. D. McCollister, and V. K. RoweCite this: J. Agric. Food Chem. 1960, 8, 1, 47–51Publication Date (Print):January 1, 1960Publication History Published online1 May 2002Published inissue 1 January 1960https://pubs.acs.org/doi/10.1021/jf60107a012https://doi.org/10.1021/jf60107a012research-articleACS PublicationsRequest reuse permissionsArticle Views71Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts