Size, shape and distribution-controlled silver nanoparticles (AgNps) were produced by a rapid and efficient method either in solvent or in polymer matrix by which the silver ion is reduced and a polymer matrix is simultaneously generated in the presence of various photoinitiators by the means of UV light. 2-Mercaptothioxanthone (TX-SH), Thioxanthone (TX) and TX+ Thiophenol were used as photoinitiator systems for the polymerization of PEGMEA/PEGDA monomer mixture in the presence of AgNO3 salt. As a summary of results, it is important to note that the size and distribution of Nps depend on the photoreducing species. Therefore TX-SH, due to thiol functionality in its structure, helped production of he 7-40 nm size and distribution-controlled AgNps in polymer matrix. In-situ prepared AgNps/Polymer nanocoatings exhibited a reflected silver mirror view as a result of aggregation depending on the irradiation time. Antibacterial efficiency and susceptibility of AgNps containing nanocomposite films were examined for t E. coli, P. aeruginosa, S. aureus and B. cereus. Obtained antimicrobial results show that photochemically prepared nanocomposites considerably increase the antimicrobial activity on Gram negative bacteria compared to Gram positive bacteria.

The Ames-Salmonella/microsome mutagenicity assay is also used to designate antimutagens and anticarcinogens that are removing the mutagen and carcinogen effects of many chemicals, including drugs and biocides. The objective of this study was to evaluate the antimutagenic potential of methanol extracts of S. limbata, S. nemerosa and S. verticillata plants by studying their effects on histidine requiring strains of Salmonella typhimurium TA1538 and TA 1535, bacterial strains in the absence and presence of a liver metabolizing system, S9-mix. These plants extract indicated important dose dependent inhibition against 4-Nitroquinoline-1-oxide and sodium azide mutagens. In the study with S9 it was determined weak positive effect of S. limbata against 2-aminoflourene. As related to these results with the detailed studies of plant originated compounds it can be possible to change them into more useful products for men.

The present study was conducted to evaluate the antimutagenic activity of methanol extract of Helichrysum plicattum ssp. plicatum plants. Antimutagenic activity of the extract was estimated by employing AMES- Salmonella/microsome assay by using Salmonella typhimurium TA 1535 and TA 1538 strains against direct acting mutagens sodium azide (NaN3), 4-nitro-1-quinoline oxide and the S9-dependent mutagen 2-amino fluorene (2AF). In this study, standard plate incorporation method was preferred to determine antimutagenic activity. In the absence of S9 metabolic activation all three doses of plant extract showed statistically significant (p < 0.05) antimutagenic activity on TA 1535 strain, but no on the TA 1538 strain. In the presence of S9 microsomal fraction, plant extract exerted moderate antimutagenic activity against the 2AF mutagen and reduced mutant colonies in the TA 1535 and TA 1538 strains. The present results indicate that H. plicatum ssp. plicatum extract has antimutagenic activity.

The Ames-Salmonella/microsome mutagenicity assay is also used to designate antimutagens and anticarcinogens that are removing the mutagen and carcinogen effects of many chemicals, including drugs and biocides [1].