Objective To investigate the indications and efficacy of clopidogrel hydrogen and aspirin in the treatment of a‐cute cerebral infarction.Methods From March 2012 to May 2014 ,168 cases of patients with acute cerebral infarction in our hospital were divided into control group and observation group according to the random principle ,each group of 84 cases ,the control group received conventional treatment on the basis of aspirin treatment ,observation group was treated by clopidogrel therapy on the basis of control group. The neurological deficits of patients in the two groups after treatment were assessed ,and the efficacy and adverse reactions were compared.Results The total effective rate of control group after treatment was 71.43% ,which was 90.48% in observation group ,the difference was significant (P<0.05). The neurological deficit scores of two groups showed no difference before treatment (P>0.05) ,and were improved after treatment ,the improvement of the ob‐servation group was better than that of the control group ,the difference was statistically significant (P<0.05).All the patients had no severe complications and adverse reactions during treatment.Conclusion Clopidogrel and aspirin can significantly im‐prove the efficacy of clinical course of acute cerebral infarction ,and reduce the adverse reactions ;the patients’ prognosis is good ,it’s worthy of promotion and application in clinical practice.
目的:观察针刺治疗对中枢性眩晕的临床疗效及针刺在中枢性眩晕患者治疗中对脑干听觉诱发电位、瞬目反射的影响,探讨以听觉诱发电位、瞬目反射作为针刺治疗中枢性眩晕疗效评估客观指标的可行性.方法:收集中枢性眩晕患者100例,随机分为两组,常规组50例,针刺组50例.两组均采用统一的常规治疗,针刺组在常规治疗的基础上加用针刺的方法治疗.观察两组患者临床疗效,脑干听觉诱发电位图形各波潜伏期(PL)和波峰间潜伏期(IPL)变化;观察瞬目反射图形各波潜伏期、双侧潜伏期差值变化.结果:常规组与针刺组临床疗效比较,差异有统计学意义(P<0.05).BAEP异常率方面,治疗前针刺组与常规组BAEP异常率间差异无统计学意义(P>0.05),治疗后,差异有统计学意义(P<0.05).常规组治疗前与治疗后比较差异显著(P<0.01,P<0.05),针刺组治疗前与治疗后比较差异显著(P<0.01),两组治疗后比较差异具有统计学意义(P<0.05).BR异常率方面:常规组治疗前与治疗后比较差异显著(P<0.01,P<0.05),针刺组治疗前与治疗后比较差异显著(P<0.01).结论:常规治疗和针刺配合常规治疗中枢性眩晕均有效,但采用针刺配合常规治疗效果更显著.常规治疗和针刺配合常规治疗均可以改善中枢性眩晕患者BAEP的Ⅰ、Ⅲ、Ⅴ波PL和Ⅰ~Ⅲ、Ⅲ~Ⅴ、Ⅰ~VIPL,可以改善BR各波潜伏期、双侧潜伏期差值,从而降低异常率,且针刺配合药物治疗优于单纯药物治疗.
目的:探讨氢氯吡格雷联合阿司匹林治疗急性进展性脑梗死的临床疗效。方法将接受治疗的100例急性进展性脑梗死患者按随机数字表法分成对照组和观察组,各50例。对照组采用氢氯吡格雷治疗,观察组在对照组基础上联合应用阿司匹林治疗。结果观察组患者治疗有效率为92.00%,优于对照组的80.00%( P<0.05);观察组神经功能缺损评分为(10.77±6.38)分,优于对照组的(16.54±6.68)分( P<0.05);观察组血液流变学改善情况优于对照组( P<0.05)。结论采用氢氯吡格雷联合阿司匹林治疗急性进展期脑梗死患者,可有效改善缺氧、缺血症状,有助于促进神经功能的恢复和血流变学的改变,值得临床推广。
目的:探讨硝苯地平联合酒石酸美托洛尔治疗高血压的疗效。方法选取我院2013‐01—2015‐02收治的200例高血压患者,采取双盲法随机分为观察组(n=100)和对照组(n=100),观察组给予硝苯地平联合酒石酸美托洛尔治疗,对照组给予硝苯地平治疗,比较2组治疗效果。结果观察组总有效率92.0%(92/100),对照组为69.0%(69/100),2组疗效对比差异有统计学意义(P<0.05);2组均未发生严重不良反应。结论硝苯地平联合酒石酸美托洛尔治疗高血压疗效显著,值得临床推广与应用。