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1Piperidine derivatives and process for the manufacture of the same

Lee John,Werner Freudenberg

1944引用：25

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2PIPERIDINE DERIVATIVES. PART 1. LOBELAN AND RELATED COMPOUNDS

J Lee,W Freudenberg

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPIPERIDINE DERIVATIVES. PART 1. LOBELAN AND RELATED COMPOUNDSJOHN LEE and WERNER FREUDENBERGCite this: J. Org. Chem. 1944, 09, 6, 537–546Publication Date (Print):November 1, 1944Publication History Published online1 May 2002Published inissue 1 November 1944https://pubs.acs.org/doi/10.1021/jo01188a007https://doi.org/10.1021/jo01188a007research-articleACS PublicationsRequest reuse permissionsArticle Views257Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

1944JOURNAL OF ORGANIC CHEMISTRY（1944）引用：22

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3The Chemistry of Naturally Occurring Monoanhydrohexitols. II. Synthetic Tetramethylstyracitol1

W Freudenberg,JT Sheehan

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Chemistry of Naturally Occurring Monoanhydrohexitols. II. Synthetic Tetramethylstyracitol1Werner Freudenberg and John T. SheehanCite this: J. Am. Chem. Soc. 1940, 62, 3, 558–560Publication Date (Print):March 1, 1940Publication History Published online1 May 2002Published inissue 1 March 1940https://doi.org/10.1021/ja01860a032Request reuse permissionsArticle Views48Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (313 KB) Get e-Alertsclose Get e-Alerts

1940引用：10

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4A New Synthesis of <i>l</i>-Galactose. The Structure of α- and β-Diacetone Dulcitol

R. A. Pizzarello,Werner. Freudenberg

1939Journal of the American Chemical Society（1939）引用：13

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5A New Synthesis Of L-Galactose. The Structure Of Alpha- And Beta-Diacetone Dulcitol

R. A. Pizzarello,Werner. Freudenberg

1939JOURNAL OF THE AMERICAN CHEMICAL SOCIETY（1939）引用：14

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6A New Synthesis of l-Galactose. The Structure of α- and β-Diacetone Dulcitol

R. A. Pizzarello,Werner Freudenberg

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA New Synthesis of l-Galactose. The Structure of α- and β-Diacetone DulcitolR. A. Pizzarello and Werner. FreudenbergCite this: J. Am. Chem. Soc. 1939, 61, 3, 611–613Publication Date (Print):March 1, 1939Publication History Published online1 May 2002Published inissue 1 March 1939https://doi.org/10.1021/ja01872a019RIGHTS & PERMISSIONSArticle Views116Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (350 KB) Get e-Alerts Get e-Alerts

1939Journal of the American Chemical Society（1939）引用：14

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7Selenium Dehydrogenation of Napelline

E F Rogers,W Freudenberg

1938Science (New York, NY)（1938）引用：3

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8The Preparation of Diacetone Sugars

H Van Grunenberg, C Bredt,W Freudenberg

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation of Diacetone SugarsH. Van Grunenberg, C. Bredt, and Werner FreudenbergCite this: J. Am. Chem. Soc. 1938, 60, 6, 1507Publication Date (Print):June 1, 1938Publication History Published online1 May 2002Published inissue 1 June 1938https://doi.org/10.1021/ja01273a502RIGHTS & PERMISSIONSArticle Views198Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (136 KB) Get e-Alerts Get e-Alerts

1938Journal of the American Chemical Society（1938）引用：51

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9The Chemistry of Naturally Occurring Monohydrohexitols1

W Freudenberg,EF Rogers

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Chemistry of Naturally Occurring Monohydrohexitols1Werner Freudenberg and E. F. RogersCite this: J. Am. Chem. Soc. 1937, 59, 9, 1602–1605Publication Date (Print):September 1, 1937Publication History Published online1 May 2002Published inissue 1 September 1937https://pubs.acs.org/doi/10.1021/ja01288a009https://doi.org/10.1021/ja01288a009research-articleACS PublicationsRequest reuse permissionsArticle Views44Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

1937Journal of the American Chemical Society（1937）引用：35

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10New Alkaloids in Aconitum Napellus<sup>1</sup>

Werner Freudenberg,E. F. Rogers

1937Journal of the American Chemical Society（1937）引用：15

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11New Dismantling Products Of Aconitin Bases (Iii. Announcement On The Aconitum-Alkaloid)

E. F. Rogers,Werner Freudenberg

1937BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT（1937）引用：1

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12The Structure of Β-Chloral Glucose

W Freudenberg, AM Vajda

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structure of β-Chloral GlucoseWerner Freudenberg and Albert M. VajdaCite this: J. Am. Chem. Soc. 1937, 59, 10, 1955–1957Publication Date (Print):October 1, 1937Publication History Published online1 May 2002Published inissue 1 October 1937https://pubs.acs.org/doi/10.1021/ja01289a048https://doi.org/10.1021/ja01289a048research-articleACS PublicationsRequest reuse permissionsArticle Views45Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

1937JOURNAL OF THE AMERICAN CHEMICAL SOCIETY（1937）引用：10

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13Neue Abbauprodukte Der Aconitbasen (III. Mitteil. Über Aconitum‐Alkaloide)

E. F. Rogers,Werner Freudenberg

Berichte der deutschen chemischen Gesellschaft (A and B Series)Volume 70, Issue 2 p. 349-354 Berichte Neue Abbauprodukte der Aconitbasen (III. Mitteil. über Aconitum-Alkaloide) E. F. Rogers, E. F. Rogers Chem. Institut d. Fordham University, New York CitySearch for more papers by this authorWerner Freudenberg, Werner Freudenberg Chem. Institut d. Fordham University, New York CitySearch for more papers by this author E. F. Rogers, E. F. Rogers Chem. Institut d. Fordham University, New York CitySearch for more papers by this authorWerner Freudenberg, Werner Freudenberg Chem. Institut d. Fordham University, New York CitySearch for more papers by this author First published: 10. Februar 1937 https://doi.org/10.1002/cber.19370700232AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 W. A. Jacobs u. R. C. Elderfield, Journ. Amer. chem. Soc. 58, 533 [1936]. 2 W. Freudenberg, Ber. dtsch. Chem. Ges. 69, 1962 [1936]. 3 R. Majima u. K. Tamura, Justus Liebigs Ann. Chem. 526, 116 [1936]. 4 Über die Zusammensetzung des amorphen Aconitins vergl. H. Schulze u. G. Berger, Arch. Pharmaz. 262, 553 [1924] und G. Trier, Die Alkaloide, S. 727 (Borntraeger 1931). 5 Für die Überlassung dieses Materials sei der Firma E. Merck, Darmstadt, auch an dieser Stelle bestens gedankt. 6 Mikrochem. 11, 140 [1931]. 7 Ber. dtsch. Chem. Ges. 66, 1274 [1933]. 8 R. Kuhn u. F. F. Moeller, Angew. Chem. 47, 145 [1934]. 9 Journ. Amer. chem. Soc. 45, 2171 [1923]. 10 O. Diels u. W. Gaedke, Ber. dtsch. Chem. Ges. 58, 1231 [1925]. 11 Die drei letzten Substanzen sind aufgeführt im Hinblick auf die Ähnlichkeit dieser Produkte mit den neutralen Substanzen, über die R. Majima u. K. Tamura (l. c.) berichten. 12 Ind. engin. Chem. 28, Analyt. Edit. 8, 219 [1936]. 13 J. Houben, Methoden der organ. Chem., 3. Aufl., Bd. II, S. 498. Volume70, Issue210. Februar 1937Pages 349-354 ReferencesRelatedInformation

1937Berichte der deutschen chemischen Gesellschaft (A and B Series)

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14New Alkaloids In Aconitum Napellus

Werner Freudenberg,E. F. Rogers

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Alkaloids in Aconitum Napellus1Werner Freudenberg and E. F. RogersCite this: J. Am. Chem. Soc. 1937, 59, 12, 2572–2575Publication Date (Print):December 1, 1937Publication History Published online1 May 2002Published inissue 1 December 1937https://doi.org/10.1021/ja01291a028RIGHTS & PERMISSIONSArticle Views150Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (420 KB) Get e-Alerts Get e-Alerts

1937JOURNAL OF THE AMERICAN CHEMICAL SOCIETY（1937）引用：23

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15Zur Struktur Des Aconitins

Werner Freudenberg

Berichte der deutschen chemischen Gesellschaft (A and B Series)Volume 69, Issue 8 p. 1962-1965 Article Zur Struktur des Aconitins† Werner Freudenberg, Werner Freudenberg Kaiser-Wilhelm-Institut für Medizin. Forschung, Heidelberg, Institut für ChemieSearch for more papers by this author Werner Freudenberg, Werner Freudenberg Kaiser-Wilhelm-Institut für Medizin. Forschung, Heidelberg, Institut für ChemieSearch for more papers by this author First published: 5. August 1936 https://doi.org/10.1002/cber.19360690831Citations: 7 † Für die Überlassung des Ausgangsmaterials danke ich den Firmen E. Merck, Darmstadt, und Merck & Co., Rahway/N.J., U.S.A. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume69, Issue85. August 1936Pages 1962-1965 RelatedInformation

1936Berichte der deutschen chemischen Gesellschaft (A and B Series)引用：11

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16Quantitative Isotopic Exchange Reactions in the Carbohydrate Group1

WH Hamill,W Freudenberg

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuantitative Isotopic Exchange Reactions in the Carbohydrate Group1W. H. Hamill and Werner FreudenbergCite this: J. Am. Chem. Soc. 1935, 57, 8, 1427–1430Publication Date (Print):August 1, 1935Publication History Published online1 May 2002Published inissue 1 August 1935https://pubs.acs.org/doi/10.1021/ja01311a013https://doi.org/10.1021/ja01311a013research-articleACS PublicationsRequest reuse permissionsArticle Views37Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

1935JOURNAL OF THE AMERICAN CHEMICAL SOCIETY（1935）引用：27

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17The Degradation of L-Arabinal to L-Erythrose1

GE Felton,W Freudenberg

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Degradation of l-Arabinal to l-Erythrose1George E. Felton and Werner FreudenbergCite this: J. Am. Chem. Soc. 1935, 57, 9, 1637–1640Publication Date (Print):September 1, 1935Publication History Published online1 May 2002Published inissue 1 September 1935https://pubs.acs.org/doi/10.1021/ja01312a039https://doi.org/10.1021/ja01312a039research-articleACS PublicationsRequest reuse permissionsArticle Views79Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

1935Journal of the American Chemical Society（1935）引用：24

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18STUDIES ON CARBOHYDRATE METABOLISM

W Freudenberg, GE Felton

Previous studies of carbohydrate metabolism have been limited almost exclusively to naturally occurring saturated sugars. Very little attention has been devoted to the fate of the unsaturated and anhydro sugars in the organism. Even though these unsaturated sugars occur very rarely in nature, information concerning their fate in the body would be of value in determining the mechanism of sugar metabolism. Winter (1) reported that glucal injected into hypoglycemic rabbits relieves insulin convulsions, rebalancing the blood sugar level within a short period of time. The close chemical relation between glucal and 2-glucodesose led Winter (2) to a study of the physiological behavior of the latter substance. It proved, however, to be inactive. Kondo (3) showed that glucal after subcutaneous or oral administration was excreted by the rabbit in the urine in the form of 2-glucodesose. 2-Glucodesose itself after being given to rabbits was excreted unchanged. Only 2 to 3 per cent could be recovered from the urine as 2-glucodesose-pnitrophenylhydrazone. With the exception of a study on the physiological action of cr-glucosan (4) no other work has been done on unsaturated and anhydro sugars in respect to their physiological significance. The great chemical reactivity of glucal as a representative unsaturated sugar is illustrated by (I) to (V). Oxidation leads to d-mannose (II) and eventually to d-glucose (III) ; reduction to hydroglucal (IV) ; addition of water finally to 2-glucodesose (V).

1933JOURNAL OF BIOLOGICAL CHEMISTRY（1933）引用：4

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19THE PREPARATION OF SARCOLACTIC ACID

W Freudenberg

In spite of the important role that optically active sarcolactic acid plays in many fields of biochemistry and physiology, there is no satisfactory method of preparing this acid.The procedure of Wislicenus ( 1) is long and results in poor yields.Meat extract is suspended in water and the proteins removed by treating several times with 90 per cent alcohol.The filtrate is evaporated, acidified with sulfuric acid, and extracted six times with ether.The resulting extract is converted into the lead salt.This is decomposed by means of H&S and finally a zinc salt is prepared, which must be recrystallized several times to obtain constant rotation.Klimenko (2) improved this method and was able to increase the yield to 1 to 2 per cent, calculated on the basis of meat extract employed.Jungfleisch and Godchot's (3) method of separating the lactic acid antipodes by means of the quinine salt yields only the levorotatory form.It is almost impossible to obtain sarcolactic acid or its salts.Only partial separation is possible when c&lactic acid is resolved into its optically active components by means of the difference in solubility of their morphine salts in water.An interesting paper by Kimura (4) reports the formation of optically active lactic acid when glucosamine or d&lactic acid is fermented by Bacillus prodigiosus and Bacillus subtilis.The amounts of sarcolactic acid isolated are, however, extremely small.During an investigation1 on the constitutional relationship of lactic acid and alanine, it was necessary to obtain large quantities of sarcolactic acid.The new method described is so simple that

1932Journal of Biological Chemistry（1932）引用：1

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20Über Die D ‐Threose

Werner Freudenberg

Berichte der deutschen chemischen Gesellschaft (A and B Series)Volume 65, Issue 2 p. 168-170 Article Über die d-Threose† Werner Freudenberg, Werner Freudenberg Departement of Chemistry, Iowa State college, Ames, Iowa, U.S.A.Search for more papers by this author Werner Freudenberg, Werner Freudenberg Departement of Chemistry, Iowa State college, Ames, Iowa, U.S.A.Search for more papers by this author First published: 3. Februar 1932 https://doi.org/10.1002/cber.19320650211 † Diese Untersuchung wurde ermöglicht durch finanzielle Unterstützung der Rockefeller-Foundation. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume65, Issue23. Februar 1932Pages 168-170 RelatedInformation

1932Berichte der deutschen chemischen Gesellschaft (A and B Series)

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