It is the most pressing task that fast and effective analysis methods monitor the inherent qualities of traditional Chinese medicine (TCM) and its corresponding extract products as a complicated mixture system. Owing to the unique fingerprint character and extensive applicability to test sample, infrared spectral method has been used in many research fields. In recent years, Fourier transform infrared spectroscopy (FT-IR), accompanied with the development of spectroscopic technology and combined with computer science, plays an important role in the TCM research. In this paper, we use FT-IR, second derivative infrared spectroscopy and two-dimensional correlation infrared spectroscopy (2D-IR) step by step to analyze the lipophilic constituents in Angelica extracted by two different extract crafts. As a result, all spectra can not only supply lots of structural information of main constituents in the complicated system, but also can differentiate the tiny differences between the similar systems according to the infrared macro-fingerprint characters. This is a very quick, effective and well repetitive method for monitoring the process of the TCM.

Traditional Chinese medicine (TCM) formula particles and their supplementary materials were studied via Fourier transform infrared spectroscopy (FTIR). It can be seen from the spectra that the formula particles from different pharmaceutical factories have great disparity in the contents and sorts of supplementary materials. The spectra could be assigned directly when the formula particles have lower contents of supplementary materials; whereas the contents higher, difference technology could be used to improve the resolution. Thus the TCM formula particles could be identified one by one. It is proved that FTIR is an easy, fast, reliable and impelling method in the quality control of TCM formula particles.

A method of using Fourer transform infrared spectroscopy (FTIR) to detect 36 Ganoderma lucidun products rapidly and undamaged is reported. As the result, each of the samples has its characteristic infrared spectrum. By the difference of the relative intensity of those absorption peaks, different kinds of Ganoderma lucidums products can be detected. It is very fast, simple, reliable and has no solution effects.

Collocalia esculenta L.is called Yanwo in China.A rapid and non-destructive method,Fouriertransform infrared spectroscopy(FTIR),for the classification of six yanwo,which are come from Indonesia,Vietnam,Malaysia,Thailand,Philippines and Hong Kong.They have their own characteristic infrared spectra.The six yanwo can be classified by the relative intensity of those absorption peaks.It is a very fast,simple,reliable method.

The thermal stability of the natural product of rutin was studied by Fourier Transform Infrared Spectroscopy (FTIR) in this paper for the first time. To monitor the changing of rutin in real time,the temperature-control accessory was also used to in-situ follow the thermal behavior. It is demonstrated that as the temperature increased from 25 degrees C to 270 degrees C, the thermally-induced denaturation of rutin was accompanied by the oxidation and thermal discomposed procedure. The structure of rutin changed at a lower temperature (75 degrees C). This is not only indicating the existence of an intermediate state,but also approved that the stability of rutin is poor. While at the higher temperature (270 degrees C),rutin discomposed into two results. It is proved that this method is fast,accurate and having no solvent effect. Samples can thus be examined undestroyed.

In this paper,near-infrared diffuse reflectance spectroscopy(NIRDRS) method was used as a quantitative tool to measure the solid mixture of rutin and vitamin C by collecting NIR spectra in the range 7 000-3 900 cm(-1). The quantitative mathematics model was established with partial least squares (PLS) method. The correlation coefficient was 99.75%,the standard error of Rutin was 0.363%,and the standard error of Vitamin C was 1.078%. The methods are rapid,exact and nondestructive to samples. The components of the samples can be individually analyzed with high accuracy and precision,so NIRDRS can be a useful method of quality control of pharmaceuticals in the future.

中医学饮食疗法具有丰富的药材资源、宝贵的临床经验、完善的食疗理论,中国现代保健食品是在中医学饮食疗法的基础上发展起来的.我们对中国保健食品进行了历时3年比较全面和系统的研究,并将研究中所获得的结果和资料转录成电子形式并运用最先进的多媒体互动信息技术来组织和管理.信息系统可以将这些研究内容以一种快捷、方便的形式供用户查索和参考.

A fast atom bombardment mass spectrometric study of the meso-substituent effect of octaethylporphyrins (OEPX, X = NH2, CH3, H, CHO, Cl, CN, NO2) is reported. The intensity of the [M + H] + ion peaks was estimated quantitatively using an external standard, which was observed to be correlated linearly with the basicity (pK3) of the OEPX. The pK3 value of the OEPXs was obtained by titration with perchloric acid and it was observed to be correlated linearly with Hammett's sigma-P value, with a rho-value of 1.38.

AbstractMechanisms are proposed for the formation of M+, [M + 2H]+ and [M + 3H]+ ions in the fast atom bombardment (FAB) mass spectra of 4‐(2,2,6,6‐tetramethyl‐1‐oxyl)‐piperidol and its carboxylates. Free radical quenching induced by the fast atom beam has been observed. The effects of temperature on the radical quenching and of acid on the FAB mass spectra are discussed. The experiment showed that the volatile liquid samples with vapour pressures higher than that for glycerol produced M+ even‐electron molecular ions, and the FAB mass spectra were similar to the corresponding electron ionization mass spectra. For the solid samples, it was found that the free radicals were quenched during the FAB process so that the mononitroxide and dinitroxide compounds produced [M + 2H]+ and [M + 3H]+ ions, respectively. Further experiments showed that the intensities and stabilities of [M + 2H]+ and [M + 3H]+ ions could be improved by addition of acids.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface precipitation technique in fast atom bombardment mass spectrometryMeiyi. Zhang, Xiyun. Liang, Yuyi. Chen, and Xiaoguang. LiangCite this: Anal. Chem. 1984, 56, 13, 2288–2290Publication Date (Print):November 1, 1984Publication History Published online1 May 2002Published inissue 1 November 1984https://pubs.acs.org/doi/10.1021/ac00277a006https://doi.org/10.1021/ac00277a006research-articleACS PublicationsRequest reuse permissionsArticle Views58Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts