Digital biosensors facilitate real-time, remote, precise disease detection and biochemical analysis.

In the context of anti-cellular catalytic permutations, the development of thermally-induced nanotechnology is of great importance. In this study, iron oxides (Fe 2 O 3 ) decorated silver (Ag) core–shell nanocomposite was prepared using a green thermal decomposition process without using any additional chemicals. The nanocomposite was characterized for its composition, phase interactions, morphology, and stability using spectroscopic, thermogravimetric, and microscopic techniques. The resultant nanocomposite were also investigated against different types of bacteria and cancer cell lines. Both Gram-positive bacteria ( Staphylococcus aureus ) and Gram-negative bacteria ( Klebsiella spp., E. coli , and Pseudomonas ) growth was inhibited by the Ag/Fe 2 O 3 nanocomposite. The highest 19 mm zone of inhibition (ZOI) was found for Staphylococcus aureus by the combined effect of Ag and Fe 2 O 3 . The antibiofilm efficacy of the prepared nanocomposites showed biofilm destruction of 82.56% Staphylococcus aureus and 51.06% Klebsiella spp. Furthermore, the nanocomposite resulted in 80–90% death of Hela and BHK-21 cells but displayed lower cell toxicity in the case of the Vero cell line. This pathway of nanocomposites preparation with particle surface engineering would open new doors in the fields of nanobiotechnology and nanobiomedical applications.

The worldwide pandemic situation of COVID-19 generates a situation in which healthcare resources such as diagnostic kits, drugs and basic healthcare infrastructure were on shortage throughout the period, along with negative impact on socio-economic system. Standardized public healthcare models were missing in pandemic situation, covering from hospitalized patient care to local resident's healthcare managements in terms of monitoring, assess to diagnosis and medicines. This exploratory and intervention-based study with the objective of proposing COVID-19 Care Management Model representing comprehensive care of society including patients (COVID-19 and other diseases) and healthy subjects under integrated framework of healthier management model. Shifting policy towards technology-oriented models with well-aligned infrastructure can achieve better outcomes in COVID-19 prevention and care. The planned development of technical healthcare models for prognosis and improved treatment outcomes that take into account not only genomics, proteomics, nanotechnology, materials science perspectives but also the possible contribution of advanced digital technologies is best strategies for early diagnosis and infections control. In view of current pandemic, a Healthier Healthcare Management Model is proposed here as a source of standardized care having technology support, medical consultation, along with public health model of sanitization, distancing and contact less behaviours practices. Effective healthcare managements have been the main driver of healthier society where, positive action at identified research, technology and management segment more specifically public health, patient health, technology selection and political influence has great potential to enhanced the global response to COVID-19. The implementation of such practices will deliver effective diagnosis and control mechanism and make healthier society.

COVID-19 risk spread rapidly with several clinical manifestations and public health challenges. Research and innovation in advanced materials should be focused on solving critical problems associated with diagnosis, treatment and control models. Important challenges of COVID-19 public health system indicated to need of solutions based on cost, quality and universal availability in sustainable model. Standard healthcare models can be achieved by advanced technology of Artificial intelligence, IoT, Database analytics and advanced materials more effectively for mass community. Next-generation ("smart") materials have capacity to contribute to theranostics models in better way with high accuracy in terms of performance and reliability. In summary, engineered nanoparticles and advanced technologies have translational potential. Being public health professionals, technologist and materials researchers involved in the prognosis research should develop certain priorities for the society.

World Health Organization (WHO) has expressed great concern about the pandemic of Coronavirus (COVID-19) and said that there is a need to control it at the high end. To strengthen this fight against COVID-19, International Association of Advanced Materials (IAAM) intends to provide a forum for high-tech healthcare. Foreseeing the current crisis, IAAM called a multi-lateral consortium to discuss the possibilities of developing a medical technology to control the spreading of coronavirus with the help of interdisciplinary experts from multiple countries. This innovation is perpetuated to create multi-lateral cooperation in the area of 'healthcare innovation and technology'. Adaptation of advanced technologies and their logical integration according to contemporary healthcare measures could be a smart strategy for epidemic management activities. Establishing an advanced phenotype model for prognosis is an important step in the prevention of infectious disease management such as COVID-19. This article has overviewed the global situation, efforts, and prospective of coronavirus pandemic.