Objective:To investigate the effect of multiple medications on the risk of small intestinal bacterial overgrowth(SIBO)in the elderly.Methods:Clinical data of 85 inpatients in the Department of Geriatrics, the First Hospital of Lanzhou University undergone HMBT from August 2017 to April 2021 were retrospectively analyzed.According to the HMBT results, they were divided into a SIBO(+ )group and a SIBO(-)group.Polypharmacy was defined as ≥ 5 types of medications.We analyzed the difference in the rate of polypharmacy between the two groups.Results:A total of 85 hospitalized elderly patients were included in the study.Of these patients, 38(44.71%)tested positive for SIBO.Polypharmacy occurred in 41 patients(48.24%). There were significant differences in types of drugs and polypharmacy between the SIBO(+ )group and the SIBO(-)group( t=3.01 and χ2=14.33, P<0.05 for both). Moreover, polypharmacy was a risk factor for SIBO( P=0.017, OR=10.85, 95% CI: 1.52-77.29). Among 14 commonly used drugs, gastrointestinal motility drugs were closely related to SIBO.There was a positive correlation between polypharmacy and the change in hydrogen levels at 90 min( P=0.040, r=0.22, 95% CI: 0.01-0.42). Conclusions:Polypharmacy is correlated with SIBO in the elderly, is a risk factor for SIBO and is helpful in clinical practice to assess the risk of SIBO and decide further examinations, contributing to early diagnosis and early treatment.

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随着网络信息技术的进一步发展,网络主播这个行业应运而生.直播行业方兴未艾,展现出庞大的潜力,但也暴露出很多问题,尤其是利用网络直播进行诈骗的案件已经屡见不鲜.默示诈骗与不作为诈骗都具备缄默性,但对二者的界限把握往往不甚清晰.通过对近日发生的一起网络主播诈骗事件进行简要介绍和法理分析,进一步厘清默示诈骗与不作为诈骗的边界,以期为实务部门准确认定犯罪形态提供参考.

地方立法权的扩容,对我国设区市的地方立法水平提出了更高要求.本文通过对浙江、甘肃二省新获立法权的设区市地方立法现状进行比较分析,从各自设区市立法的数量、质量以及立法倾向入手,找出分属东西部地区的二省设区市地方立法各自存在的问题,提炼总结出我国当前设区的市地方立法的困境并提出解决路径.