Objective:To observe clinical features of sleep structure and sleep disorder in elderly patients with geriatric syndrome, and to analyze the correlation between sleep disorder and geriatric syndrome.Methods:This was a cross-sectional study.Patients aged ≥60 years(73.5±4.1 years)diagnosed as geriatric syndrome were enrolled as a geriatric syndrome group(n=200). The age-and gender-matched elderly subjects being healthy confirmed by regular health checking in our hospital during the same period were enrolled as a control group(n=200). The Pittsburgh Sleep Qualit Index(PSQI)scores and polysomnography(PSG)indexes were observed in the two groups.Results:The fasting blood glucose level was higher in the geriatric syndrome group than in the control group( P<0.05). The PSQI score was higher in the geriatric syndrome group than in the control group(7.8±1.7 vs.6.3±1.2, P<0.01). The total score of PSQI was positively correlated with number of elderly syndrome components in the geriatric syndrome group( r=0.95, P<0.01). There was no significant difference in sleep stage S1 and total recording time between the two groups( P>0.05). The rapid eye movement sleep(REM)time, sleep efficiency, slow wave sleep, sleep latency were lower, while the REM intensity, REM density, sleeping time, awakening numbers, awakening time, sleep stage S2 and REM activity were higher in the geriatric syndrome group than in the control group( P<0.05). PSG test results showed that there was no statistical difference in total recording time and sleep stage S1 between the two groups( P>0.05). The sleep time, sleep efficiency, slow wave sleep(SWS), REM sleep latency and REM sleep time were lower the geriatric syndrome group than in the control group( P<0.05). Conclusions:The sleep quality is worse along with the increase of the number of geriatric syndromes components in elderly patients.PSG monitoring technology is helpful for early detection and identification of insomnia in patients with geriatric syndrome.

目的:观察阳和健脾汤对下肢动脉硬化闭塞症(ASO)的临床疗效.方法:将66例ASO患者随机分为2组各33例.对照组采用前列地尔等基础治疗,观察组在对照组治疗方案的基础上应用阳和健脾汤治疗.结果:总有效率对照组72.7％,观察组97.0％,2组比较,差异有统计学意义(P＜0.05);治疗后,2组疼痛积分、冷感积分、踝肱比值(ABI)及皮温变化情况分别与治疗比较,差异均有统计学意义(P＜0.05);2组间以上指标分别比较,差异均有统计学意义(P＜0.05).治疗后,2组甘油三酯、高密度脂蛋白胆固醇各项指标比较,差异均无统计学意义(P＞0.05);2组间总胆固醇及低密度脂蛋白胆固醇指标比较,差异均有统计学意义(P＜0.05).结论:阳和健脾汤可改善患者症状,降低血液黏稠度,对肢端微循环、皮温及疼痛有较大改善,在临床治疗中值得使用.

Objective To analyze the features of sleep monitoring in obstructive sleep apnea syndrome with hypertensive patients.Methods OSAHS patients with hypertension as study group 1,OSAHS patients with normal blood pressure as the study group 2,and simple snoring patients as the control group,the application polysomnography instrument was used in the three group.Results ① The awakening time of study group 1,study group 2 was increased more significantly than that of the control group,shallow sleep of study group 1 increased more significantly than that of the study group 2 and control group;moderate sleep decreased more significantly than that of the study group 2 and control group(P0.05).② respiratory hypopnea index,respiratory tentative index in study group 1 were significantly higher than those in the study group 2(P0.05).③ apnea time in the percentage of total sleep time in study group 1 was increased more significantly than that of the study group 2(P0.05).④ minimum oxygen saturation in study group 1 was significantly higher than that of the study group 2(P0.05).Conclusions The degree of respiratory disorder in OSAHS patients with hypertension are more severe than that in patients with normal blood pressure,and relatively poor sleep quality.

目的:观察百灵丹治疗高血压病的临床疗效.方法:应用百灵丹治疗高血压病82例,并设立西药对照组43例,治疗中止组25例,观察三组患者的血压变化与常见症状的疗效.结果:百灵丹的降压疗效与西药对照无差异(P＞0.05),而对高血压病常见症状的疗效百灵丹优于西药(P＜0.01).

目的了解学生中蠕形螨的感染情况及与面部疾患的关系.方法采用透明胶纸粘贴法对我校成教学院411名学生面部人体蠕形螨感染情况进行调查.结果有蠕形螨寄生者146例,总感染率为35.5%,男性感染率为41.1%,女性为32.3%,二者无显著性差异(P＞0.05).

目的:观察百灵丹治疗高脂血症的临床疗效与百灵丹对高脂血症大鼠脂代谢及血液流变学的影响.方法:应用百灵丹治疗高脂血症112例,3个月为一疗程,采用自身对照法,观察治疗前后血脂变化情况;采用喂食高脂饲料方法复制大鼠高脂血症模型,检测各组大鼠血清及肝组织血脂含量和血液流变学指标变化.结果:112例高脂血症治疗前后血脂变化均有显著差异(P<0.05或P<0.01);百灵丹可降低高脂血症大鼠血清TC、TG、LDL-C、HDL-C、TC/HDL-C及肝组织TC、TG含量(P<0.05或P<0.01),并改善血液流变学指标.结论:百灵丹对高脂血症降脂作用确切对高脂血症大鼠有降脂及改善血液流变学指标的作用.

目的观察百灵丹对高脂血症大鼠脂代谢及血液流变学的影响.方法采用喂食高脂饲料方法复制大鼠高脂血症模型,检测各组大鼠血清及肝组织血脂含量及血液流变学指标变化.结果百灵丹可降低高脂血症大鼠血清TC、TG、LDL-C、HDL-C、TC/HDL-C及肝组织TC、TG含量(P＜0.05或0.01),并改善血液流变学.结论百灵丹对高脂血症大鼠有降脂及改善血液流变学作用.