对于男性朋友来说,对性能力的关心绝对排在前位.下列几个问题,是男人们比较关心的"性"问题,这里为大家一一释疑. 性生活频率多少算正常? 由于个体间的性欲差别很大,即使同一年龄段的不同夫妻的性生活频率也可以相差很多,因此千万不要把别人的频率当作自己的标准.大多数人可以参考以下两种标准.

PURPOSE:Premature ejaculation (PE) is one of the most common male sexual dysfunctions. Local anesthetics (LAs) and dapoxetine are frequently used to treat PE; however, previous studies show variable efficacy. This study aims to determine the efficacy of LAs and dapoxetine using a novel classification based on neurophysiological tests. MATERIALS AND METHODS:This multicenter cohort study enrolled adult men (568) with an intravaginal ejaculatory latency time (IELT) ≤2 minutes. Patients were divided into 4 groups according to the results of neurophysiological tests and assigned different treatments for 12 weeks: 1) penile sensory hyperexcitability type (Sens)-LAs; 2) penile sympathetic hyperexcitability type (Symp)-dapoxetine; 3) mixed type (Mixed)-both LAs and dapoxetine; 4) normal type (Norm)-both LAs and dapoxetine. Self-estimated IELT and patient-reported outcomes were recorded. RESULTS:The total percentage of men achieving IELT >2 minutes and ≥5 minutes after treatment were 82.7% and 76.7%, respectively. For men with abnormal results of neurophysiological tests, 401 (86.6%) had improved IELT >2 minutes after the 12-week treatment course, in which 375 (81.0%) achieved IELT ≥5 minutes. All patient-reported outcome measures improved in each group after 12 weeks of treatment, with greater improvements among those with abnormal neurophysiological tests. CONCLUSIONS:The efficacy of LAs and dapoxetine increased in PE patients with abnormal results of neurophysiological tests. This novel classification of PE using neurophysiological tests could help guide and improve efficacy of PE therapies.

OBJECTIVE:To compare the effects and complications of subinguinal microscopic ligation, laparoscopic transperitoneal varicocelectomy, laparoscopic retroperitoneal varicocelectomy, open retroperitoneal high ligation, and interventional embolotherapy in the treatment of varicocele. METHODS:We conducted a retrospective study that included 632 varicocele patients treated by subinguinal microscopic ligation (group A, n = 79), laparoscopic transperitoneal varicocelectomy (group B, n = 120), laparoscopic retroperitoneal varicocelectomy (group C, n =137), open retroperitoneal high ligation (group D, n = 283), and interventional embolotherapy (group E, n = 13). We compared the baseline and 3-month postoperative semen parameters, postoperative complications, and pregnancy rate among the five groups of patients. RESULTS:The operation time was longer in groups A ([2.02 ± 1.25] h) and E ([2.17 ± 1.02] h) than in the other three groups, while the postoperative hospital stay was the shortest in group E ([1.1 ± 0.1] d). Intestinal injury or incision bleeding occurred intraoperatively in 2 cases in group B and 1 case in group E. Postoperative scrotal edema developed in 3.7, 17, 10, and 19% of the patients in groups A, B, C, and D, respectively, but not in group E. The rate of 1-year recurrence was the lowest in group A (1.6%) and highest in group E (22%). Sperm concentration and the percentages of progressively motile sperm and morphologically normal sperm were improved postoperatively in all the patients (P < 0. 05), but there were no statistically significant differences among the five groups either in the above three parameters or in the postoperative pregnancy rate (P > 0. 05). CONCLUSION:In the surgical treatment of varicocele, laparoscopic retroperitoneal approach involves short operation time and few complications, subinguinal microscopic ligation has the advantages of little injury, rapid recovery, and few complications but requires specialized microsurgical techniques, and interventional embolotherapy leaves no incision scar and needs only local anesthesia and 1-day postoperative hospital stay, which is uitable for those with a contraindication to anesthesia.

<正>在勃起功能障碍(ED)治疗中,伴侣满意度对治疗的持续性具有重要影响。为综合分析西地那非治疗ED后患者伴侣对总体治疗满意度和有效性的反应,Montorsi F等组织进行了14项双盲、安慰剂对照研究。在这14项利用西地那非治疗ED的研究中,每位伴侣主要通过国际勃起功能评分(IIEF)中改进后、的分别评价勃起频率,维持勃起的能力和性交满意度的3个问题,评价男方的勃起功能和自己的性交满意度。在其中6项研究中,伴侣对西地那非的治疗满

OBJECTIVES:To investigate the level of AIDS knowledge among people concerned in Nanjing city in order to provide scientific evidence and constructive suggestions for the government to formulate relevant policies for AIDS control.METHODS:Three sets of questionnaires on AIDS knowledge were designed, the scores calculated, and the results evaluated.RESULTS:Of the 2,500 questionnaires issued to 4 different groups of people, 2,436 were collected back with effective answers, 991 from medical and health-related workers with the mean score of 58, 473 from college students with the mean score of 39.9, 524 from common city residents with the mean score of 42.3, and 448 from those working in high risk environment with the mean score of 47.CONCLUSIONS:The level of AIDS knowledge among people concerned in Nanjing city was far below the requirement of the nation, especially among medical and health-related workers. Efforts must be made to raise the level of AIDS knowledge of people concerned so as to enhance the prevention and treatment of the disease.

以2只屡配不孕"波尔山羊"、1只F2代杂交波尔山羊、6只"徐淮白山羊"为卵子供体,经同期发情和超排处理,腹腔镜观察卵巢卵泡发育状况后筛选出供手术采卵供体.从7只供体中采集到可用卵子39枚,采用输卵管内配子移植(GIFT)技术植入受体徐淮母羊12只.移植后连续3个发情周期妊娠鉴定表明,12只受体中有6只未返情,妊娠率为50%.2只受体产单羔,1只受体产3羔(难产).共移植39枚卵子,5枚发育为后代,配子受精发育率为13%.

以原代培养和传代培养的方法培养成年雄性毛冠鹿的皮肤细胞,对其核型进行分析,发现了一种新的核型,二倍体染色体数为2n=48,染色体正好配成24对,其中有一对为异型染色体.该对异型染色体的一条为较大的端着丝粒染色体,长度仅次于第3号染色体, C带与薄层扫描显示其异染色质丰富.另一条为较大的近端着丝粒染色体,长度介于第2号与第3号染色体之间,比其他已知核型中相应的染色体长,几乎全为异染色质.G带分析表明该对异型染色体的异染色质区域均显示一些数目不等的浅带.本文通过核型分析,对毛冠鹿的性染色体进行了初步的探讨.