基本信息
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职业迁徙
个人简介
My Research
KEYWORDS
cancer, immunology, metabolism, microbiology, microbiome, understanding how infectious agents and the microbiome regulate susceptibility to inflammatory disease
SUMMARY
The Cadwell Lab investigates how the immune system is controlled during infectious and inflammatory diseases. The immune system is tasked with defending against life-threatening infectious agents, but at the same time must avoid unnecessary reactions against beneficial microbes that are part of the microbiome. Such unwanted immune responses are implicated in a variety of chronic diseases including inflammatory bowel disease and cancer. A key research goal is to uncover the cell biological processes that control the immune response when confronted with the diverse infectious agents found in the environment. Ongoing projects include: (1) Identifying gene-microbe interactions that contribute to inflammatory bowel disease, (2) elucidating the role of the cellular process of autophagy in host-pathogen interactions, and (3) examining the viral component of the microbiome, also known as the virome.
KEYWORDS
cancer, immunology, metabolism, microbiology, microbiome, understanding how infectious agents and the microbiome regulate susceptibility to inflammatory disease
SUMMARY
The Cadwell Lab investigates how the immune system is controlled during infectious and inflammatory diseases. The immune system is tasked with defending against life-threatening infectious agents, but at the same time must avoid unnecessary reactions against beneficial microbes that are part of the microbiome. Such unwanted immune responses are implicated in a variety of chronic diseases including inflammatory bowel disease and cancer. A key research goal is to uncover the cell biological processes that control the immune response when confronted with the diverse infectious agents found in the environment. Ongoing projects include: (1) Identifying gene-microbe interactions that contribute to inflammatory bowel disease, (2) elucidating the role of the cellular process of autophagy in host-pathogen interactions, and (3) examining the viral component of the microbiome, also known as the virome.
研究兴趣
论文共 162 篇作者统计合作学者相似作者
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Simone Dallari, Vicky Martinez Pazos, Juan Munoz Eusse,Judith Wellens,Craig Thompson,Jean-Frederic Colombel,Jack Satsangi,Ken Cadwell,Serre-Yu Wong,
Scientific reportsno. 1 (2024): 186-186
Shen-Huan Liang,Shabnam Sircaik, Joseph Dainis,Pallavi Kakade,Swathi Penumutchu, Liam D. McDonough,Ying-Han Chen,Corey Frazer, Tim B. Schille,Stefanie Allert,Osama Elshafee, Maria Hänel,
Natureno. 8004 (2024): 620-627
Tadasu Iizumi, Yu Matsuzawa, Jing Yu Carolina Cen Feng, Josh Karp, Joseph N. Pucella,Ken Cadwell,Jordan E. Axelrad
Gastroenterologyno. 5 (2024): S-567-S-568
Chunyi Zhou, Miranda B Pawline,Alejandro Pironti, Sabrina M Morales, Andrew I Perault,Robert J Ulrich, Magdalena J Podkowik,Alannah Lejeune, Ashley DuMont,Francois-Xavier Stubbe, Aryeh Korman, Drew R Jones,
biorxiv(2024)
Dhaval Dixit, Victoria M. Hallisey, Ethan Y. S. Zhu,Martyna Okuniewska,Ken Cadwell,Jerry E. Chipuk,Jordan E. Axelrad,Susan R. Schwab
JOURNAL OF CLINICAL INVESTIGATIONno. 4 (2024)
Katharine Lu Yang, Briana J Mullins,Alannah Lejeune,Ellie Ivanova,Jong Shin, Sofia Bajwa,Richard Possemato,Ken Cadwell,Jose U Scher,Sergei B Koralov
Arthritis & rheumatology (Hoboken, N.J.)no. 4 (2024): 647-659
Kyung Ku Jang,Defne Ercelen, Jing Yu Carolina Cen Feng,Sakteesh V. Gurunathan, Chaoting Zhou,Luke P. Newell,Aryeh Korman,Drew R. Jones,David Hudesman, P'ng Loke,Ken Cadwell,Jordan E. Axelrad
Gastroenterologyno. 5 (2024): S-223
Shushan Sargsian, Octavio Mondragón-Palomino,Alannah Lejeune, Defne Ercelen,Wen-Bing Jin, Alan Varghese, Yvonne A. L. Lim,Chun-Jun Guo, P’ng Loke,Ken Cadwell
Microbiomeno. 1 (2024): 1-17
Jordan E. Axelrad,Defne Ercelen, Josh Karp, Jing Yu Carolina Cen Feng, Joseph N. Pucella,Ken Cadwell
Gastroenterologyno. 5 (2024): S-1460
Journal of Immunologyno. 1 (2023): 160.03-160.03
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