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Current Research and Scholarly Interests
Our research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity. The regulation of chromatin is a crucial component of DNA metabolism and processing in eukaryotic organisms. Chromatin-remodeling complexes, modified histones, and higher order chromatin structure are all factors influencing genome stability. We utilize an integrated approach of genetic, biochemical, and molecular techniques, in both yeast and mammalian systems, to examine the involvement of chromatin in processes that prevent genome instability and the pathogenesis of disease.
Our research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity. The regulation of chromatin is a crucial component of DNA metabolism and processing in eukaryotic organisms. Chromatin-remodeling complexes, modified histones, and higher order chromatin structure are all factors influencing genome stability. We utilize an integrated approach of genetic, biochemical, and molecular techniques, in both yeast and mammalian systems, to examine the involvement of chromatin in processes that prevent genome instability and the pathogenesis of disease.
研究兴趣
论文共 39 篇作者统计合作学者相似作者
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Liza Huijse, Solomon M Adams, Joshua N Burton,Julianne K David,Russell S Julian, Galit Meshulam-Simon,Harry Mickalide,Bersabeh D Tafesse,Verónica Calonga-Solís, Ivan Rodrigo Wolf,Ashby J Morrison,Danillo G Augusto,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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