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The Liquid Biopsy Laboratory, led by Director Dr. Erica Carpenter, focuses on the identification, capture, and analysis of Circulating Tumor Cells (CTCs) and cell-free DNA (cfDNA) from cancer patients. Blood, bone marrow, pleural effusions, and other non-invasively captured patient samples are used to detect biomarkers which allow: 1) early detection of disease as well as post-therapy monitoring of minimal residual disease, 2) an efficient means of determining clinical and biological response to therapy and, thus, clinical decision making, and, 3) cancer genetic phenotyping to drive personalized medicine that obviates the need for serial biopsies in a population of patients for which these procedures are difficult, risky, and insufficient. The focus of the CTM Center is driven by the needs of clinicians and translational investigators, and realized through collaborative work with investigators in the Penn School of Medicine, the Penn School of Engineering, and the Center for Personalized Diagnostics. Moreover, when it is determined that outsourcing of technology development is preferable, collaborative efforts with industry partners are actively sought, and these efforts have already been initiated in focused areas.
研究兴趣
论文共 80 篇作者统计合作学者相似作者
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Roni Ben-Ami,Qiao-Li Wang,Jinming Zhang,Julianna G. Supplee,Johannes F. Fahrmann, Roni Lehmann-Werman,Lauren K. Brais, Jonathan Nowak,Chen Yuan,Maureen Loftus,Ana Babic,Ehsan Irajizad,
GUTno. 4 (2024): 639-648
Samuele Cannas,Jacob E. Till,Kristine Kim,Michael J. LaRiviere,Charles M. Vollmer,Jennifer R. Eads,Thomas B. Karasic,Peter J. O'Dwyer,Charles J. Schneider,Ursina R. Teitelbaum, Kim A. Reiss Binder,Mark H. O'Hara,
CANCER RESEARCHno. 7 (2023)
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Susan M. Domchek, Adri Recio,Rosemarie Mick, Carolyn E. Clark,Erica L. Carpenter,Kevin R. Fox,Angela DeMichele,Lynn M. Schuchter,Michael S. Leibowitz, Michael H. Wexler, Barbara A. Vance, Gregory L. Beatty,
crossref(2023)
Jacob E. Till,Dominique Ballinger,Zhuoyang Wang, Zinat Yazdani, Carmenza Macía, Melinda Yin,Aseel Abdalla,Ali Nabavizadeh,Arati Desai,Zev A. Binder,Kandace Gollomp,Wanding Zhou,
Neuro-oncologyno. Supplement_5 (2023): v13-v13
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JCO precision oncology (2022)
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Jacob E. Till,Roni Ben-Ami,Ruth Shemer, Kristine Kim, Aseel Abdalla, Samuele Cannas,Charles M. Vollmer, Mark H. O'Hara,Ben Z. Stanger,Yuval Dor,Erica L. Carpenter
Cancer Researchno. 22_Supplement (2022): 18-19
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