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With his approach of combining physics, biology and chemistry in one department, Cissé aims to deepen the understanding of how genetic information is decoded in our . He is researching the behavior of individual molecules as well as biomolecular phase transitions in living cells that result from so-called weak and transient interactions between molecules. The scientist and his team use methods and their know-how from physics to learn more about the biophysical principles that regulate these processes in the genome. Using specially developed, super-resolution imaging techniques, they observe individual molecules and groups of molecules in living cells. This allows them to analyze what molecular events take place when a cell turns on a gene. The techniques can visualize clusters of molecules that rapidly build up and break down during gene expression.
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论文共 42 篇作者统计合作学者相似作者
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Manyu Du, Simon Hendrik Stitzinger, Jan-Hendrik Spille, Won-Ki Cho,Choongman Lee, Mohammed Hijaz, Andrea Quintana,Ibrahim I. Cisse
CELLno. 2 (2024): 331-344.e17
PROTEIN SCIENCEno. 12 (2023)
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Nature Structural & Molecular Biologyno. 5 (2021): 435-442
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