基本信息
浏览量:2
职业迁徙
个人简介
Biography
Dr. Kaczmarek carried out his undergraduate and graduate work at the University of London. He continued his research career at the University of California Los Angeles (where he learned electrophysiology), the Free University of Brussels, Belgium (where he learned how to make neural network models) and the California Institute of Technology (where he made the fundamental discovery that phosphorylation state changes ionic currents) before joining the Yale faculty in 1981. The Kaczmarek group studies biochemical changes in neurons that result in prolonged changes in the behavior of an animal or detect specific patterns of sensory inputs. He is well-known for discovering the genes for several ion channel proteins that are directly responsible for the excitability of nerve cells. His work was the first to demonstrate directly that rapid changes in phosphorylation state of ion channels occur in vivo in response to changes in the animal’s environment. Currently his lab is focused on the way mutations in these proteins may be responsible for several forms of intellectual disability and autism. He has been very fortunate to have many exceptionally talented pre- and postdoctoral trainees in his laboratory. Thirty-two of the students and postdocs from the Kaczmarek laboratory have gone on to hold tenure-track faculty positions at major institutions including Brown University, Yale University, UCSF, UCSD, Vanderbilt and many more.
Dr. Kaczmarek carried out his undergraduate and graduate work at the University of London. He continued his research career at the University of California Los Angeles (where he learned electrophysiology), the Free University of Brussels, Belgium (where he learned how to make neural network models) and the California Institute of Technology (where he made the fundamental discovery that phosphorylation state changes ionic currents) before joining the Yale faculty in 1981. The Kaczmarek group studies biochemical changes in neurons that result in prolonged changes in the behavior of an animal or detect specific patterns of sensory inputs. He is well-known for discovering the genes for several ion channel proteins that are directly responsible for the excitability of nerve cells. His work was the first to demonstrate directly that rapid changes in phosphorylation state of ion channels occur in vivo in response to changes in the animal’s environment. Currently his lab is focused on the way mutations in these proteins may be responsible for several forms of intellectual disability and autism. He has been very fortunate to have many exceptionally talented pre- and postdoctoral trainees in his laboratory. Thirty-two of the students and postdocs from the Kaczmarek laboratory have gone on to hold tenure-track faculty positions at major institutions including Brown University, Yale University, UCSF, UCSD, Vanderbilt and many more.
研究兴趣
论文共 205 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Taylor J Malone,Jing Wu,Yalan Zhang,Pawel Licznerski, Rongmin Chen, Sheikh Nahiyan, Maysam Pedram,Elizabeth A Jonas,Leonard K Kaczmarek
bioRxiv : the preprint server for biology (2024)
Cell Reportsno. 3 (2024): 113904-113904
Neuronno. 5 (2023): 612-613
JOURNAL OF NEUROTRAUMAno. 15-16 (2023): A30-A30
引用0浏览0引用
0
0
IUPHAR/BPS guide to pharmacology CITEno. 1 (2023)
British Journal of Pharmacologyno. S2 (2023): S145-S222
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn