The zebrafish reference genome sequence and its relationship to the human genome Kerstin Howe , Matthew D. Clark , Carlos F. Torroja , James Torrance , Camille Berthelot , Matthieu Muffato , John E. Collins , Sean Humphray , Karen McLaren , Lucy Matthews , Stuart McLaren , Ian Sealy , Mario Caccamo , Carol Churcher , Carol Scott , Jeffrey C. Barrett , Romke Koch , Gerd-Jörg Rauch , Simon White , William Chow , Britt Kilian , Leonor T. Quintais , José A. Guerra-Assunção , Yi Zhou , Yong Gu , Jennifer Yen , Jan-Hinnerk Vogel , Tina Eyre , Seth Redmond , Ruby Banerjee , Jianxiang Chi , Beiyuan Fu , Elizabeth Langley , Sean F. Maguire , Gavin K. Laird , David Lloyd , Emma Kenyon , Sarah Donaldson , Harminder Sehra , Jeff Almeida-King , Jane Loveland , Stephen Trevanion , Matt Jones , Mike Quail , Dave Willey , Adrienne Hunt , John Burton , Sarah Sims , Kirsten McLay , Bob Plumb , Joy Davis , Chris Clee , Karen Oliver , Richard Clark , Clare Riddle , David Elliott , Glen Threadgold , Glenn Harden , Darren Ware , Sharmin Begum , Beverley Mortimore , Giselle Kerry , Paul Heath , Benjamin Phillimore , Alan Tracey , Nicole Corby , Matthew Dunn , Christopher Johnson , Jonathan Wood , Susan Clark , Sarah Pelan , Guy Griffiths , Michelle Smith , Rebecca Glithero , Philip Howden , Nicholas Barker , Christine Lloyd , Christopher Stevens , Joanna Harley , Karen Holt , Georgios Panagiotidis , Jamieson Lovell , Helen Beasley , Carl Henderson , Daria Gordon , Katherine Auger , Deborah Wright , Joanna Collins , Claire Raisen , Lauren Dyer , Kenric Leung , Lauren Robertson , Kirsty Ambridge , Daniel Leongamornlert , Sarah McGuire , Ruth Gilderthorp , Coline Griffiths , Deepa Manthravadi , Sarah Nichol , Gary Barker , Siobhan Whitehead , Michael Kay , Jacqueline Brown , Clare Murnane , Emma Gray , Matthew Humphries , Neil Sycamore , Darren Barker , David Saunders , Justene Wallis , Anne Babbage , Sian Hammond , Maryam Mashreghi-Mohammadi , Lucy Barr , Sancha Martin , Paul Wray , Andrew Ellington , Nicholas Matthews , Matthew Ellwood , Rebecca Woodmansey , Graham Clark , James D. Cooper , Anthony Tromans , Darren Grafham , Carl Skuce , Richard Pandian , Robert Andrews , Elliot Harrison , Andrew Kimberley , Jane Garnett , Nigel Fosker , Rebekah Hall , Patrick Garner , Daniel Kelly , Christine Bird , Sophie Palmer , Ines Gehring , Andrea Berger , Christopher M. Dooley , Zübeyde Ersan-Ürün , Cigdem Eser , Horst Geiger , Maria Geisler , Lena Karotki , Anette Kirn , Judith Konantz , Martina Konantz , Martina Oberländer , Silke Rudolph-Geiger , Mathias Teucke , Christa Lanz , Günter Raddatz , Kazutoyo Osoegawa , Baoli Zhu , Amanda Rapp , Sara Widaa , Cordelia Langford , Fengtang Yang , Stephan C. Schuster , Nigel P. Carter , Jennifer Harrow , Zemin Ning , Javier Herrero , Steve M. J. Searle , Anton Enright , Robert Geisler , Ronald H. A. Plasterk , Charles Lee , Monte Westerfield , Pieter J. de Jong , Leonard I. Zon , John H. Postlethwait , Christiane Nüsslein-Volhard , Tim J. P. Hubbard , Hugues Roest Crollius , Jane Rogers , Derek L. Stemple NATURE（2013）
摘要
high-quality sequence assembly of the zebrafish genome reveals the largest gene set of any vertebrate and provides information on key genomic features, and comparison to the human reference genome shows that approximately 70% of human protein-coding genes have at least one clear zebrafish orthologue.
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