Obesity and type 2 diabetes mellitus (T2DM) are global challenges, with obesity increasing risk of T2DM. Body mass index (BMI), the conventional measure of obesity, may not accurately predict metabolic risk, especially in Asian individuals. Evaluation of alternative anthropometric indices may offer additional approaches for risk assessment. The multicenter, cross-sectional study examined whether anthropometric indices—such as waist, hip, neck, calf, and wrist circumferences, as well as waist–hip, neck–height, and waist–calf ratios—are associated with T2DM in adults with obesity. The study included 750 adults (BMI ≥ 25 kg/m2) recruited from four endocrinology centers across India. Anthropometric and clinical data were recorded using a standardized electronic form. T2DM was present in 73
Acute kidney injury (AKI) in the setting of severe thrombocytopenia represents a formidable challenge in nephrology, where both the underlying disease and therapeutic interventions carry a high risk of bleeding. Conditions such as lupus nephritis, thrombotic thrombocytopaenic purpura (TTP), haemolytic uraemic syndrome (HUS), haematological malignancies, chemotherapy-induced marrow suppression, and severe viral infections including dengue or sepsis-related disseminated intravascular coagulation often present with simultaneous kidney dysfunction and profound thrombocytopenia. In such renothrombocytopenic syndromes, initiation of kidney replacement therapy (KRT) is often lifesaving but complicated by the heightened risk of haemorrhage because of various factors including anticoagulation use, vascular access placement, and fragile haemostasis. This article reviews the unique challenges of dialysis in patients with thrombocytopenia and proposes a structured "Dialysis Toolkit" for clinicians.
The "3 ACE Check List" is an innovative framework that aims to guide clinicians in selecting appropriate anti-obesity therapy. The 3ACE list consists of nine factors, attractively, alliteratively and accurately listed in three columns. These facets represent the entire biopsychosocio- environmental spectrum of determinants of obesity. It simplifies decision making, by helping clinicians match therapeutic choices with individual patient characteristics, so as to optimize outcomes and satisfaction. We suggest the use of this model in obesity counselling and care..
Superficially, primary health care seems to have nothing in common with the esoteric science of endocrinology. Changing trends of disease prevalence have facilitated a reappraisal of this attitude. Comprehensive endocrine services are now needed at the primary care level. Endocrine specialists have already taken on the mantle of working as bariatric physicians. The future will see qualified endocrinologists working at primary care level, handling metabolic and hormonal diseases, along with comorbid conditions. This will be a welcome trend, both for public health and for the specialty’s growth.
This meta-thinking communication explores the concept of metacrinology through various prisms. The Greek prefix 'meta' has place of pride in metabolism, metamorphosis, metastasis, and meta-analysis. We now suggest its use as part of metacrinology, to convey the ever-expanding vastness of hormonal anatomy and function, as well as homeostasis and ill-health. Metacrinology can be defined in various ways. The most comprehensive definitions, however, are the study of endocrinology, beyond currently accepted pathways, paradigms, and processes, in an openminded, evidence-based manner, so as to explore and elucidate newer physical and functional facets of hormonal health and disease.
