Bidar Institute of Medical Sciences, better and abbreviated as, BRIMS is a district Government Hospital and medical college in Bidar, Karnataka with a status of autonomous institute under Government of Karnataka. College is recognised by medical council of India and affiliated to Rajiv Gandhi University of Health Sciences Karnataka.Initially was tagged to district hospital of bidar which was of 300 beds strength and was later upgraded to new BRIMS teaching hospital of 750 beds. The new building has eight stories with various departmental OTs, central lab, upgraded equipments, which was inaugurated in 2017.The Institution runs UG and PG courses in various specialities. Intake for MBBS was initially 100 annually and had been increased to 150 per annum since 2017. Admissions are through NEET UG.PG seats are in the department of Anatomy, Physiology, Biochemistry, Pharmacology, Forensic medicine and Community medicine. Seats for clinical departments are expected to start from 2018 onwards in Medicine, Surgery, Ophthal, ENT and Pediatrics. Admissions are through NEET PG.The institute is tagged with zonal pharmacovigilance centre and NODAL reference lab under NTCP (National Tuberculosis Control Programme).
Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder among reproductive-age women and is frequently associated with metabolic derangements. The coexistence of Metabolic Syndrome (MetS) in PCOS increases the risk of cardiovascular disease and diabetes, making early detection clinically essential. Aim: To determine the prevalence of PCOS and its association with Metabolic Syndrome in reproductive-age women. Methods: A cross-sectional study was conducted among 180 women aged 18-40 years attending the outpatient department of a tertiary care hospital. PCOS was diagnosed using Rotterdam criteria (2003), while MetS was defined according to NCEP ATP III guidelines. Anthropometric measurements, blood pressure, fasting glucose, and lipid profile were recorded. Data were analyzed using SPSS v25.0, with χ² and t-tests applied as appropriate; p < 0.05 was considered statistically significant. Results: The mean age of participants was 27.9 ± 4.2 years, with a mean BMI of 26.8 ± 3.9 kg/m². The overall prevalence of PCOS was 34.4% (95% CI: 27.9-41.6%), while MetS prevalence was 26.7% (95% CI: 20.9-33.3%). Among women with PCOS, 41.9% had concurrent MetS compared to 18.6% among non-PCOS women (RR = 2.25; 95% CI: 1.40-3.63; p = 0.0008). Central obesity (56.5% vs 35.6%), elevated triglycerides (51.6% vs 33.1%), and low HDL-C (61.3% vs 42.4%) were significantly more common in the PCOS group. The prevalence of PCOS rose progressively with increasing BMI (p = 0.007). Conclusion: A strong association exists between PCOS and MetS in reproductive-age women, driven mainly by central obesity and dyslipidemia. Screening for metabolic risk factors should form an integral part of PCOS management to prevent future cardiometabolic complications. Key words: Polycystic Ovary Syndrome, Metabolic Syndrome, Reproductive-age Women
Background: Alcohol-related liver disease (ALD) is a leading cause of preventable morbidity and mortality. The neutrophil-to-lymphocyte ratio (NLR) and neutrophil–lymphocyte-to-albumin (NLA) ratio are inexpensive, readily available biomarkers reflecting inflammatory and synthetic status. Objective: To evaluate the prognostic utility of neutrophil-to-lymphocyte ratio (NLR) and neutrophil–lymphocyte-to-albumin (NLA) ratio in predicting 30-day and 90-day mortality in ALD.Methods: This prospective observational study was conducted over 18 months (June 2024–November 2025) at a tertiary care teaching hospital in South India. Seventy consecutive male patients aged >18 years with alcohol-related liver disease were enrolled. NLR was calculated as the ratio of absolute neutrophil count to absolute lymphocyte count, and NLA as NLR divided by serum albumin. Patients were followed up for 90 days after discharge with mortality assessed at admission, 30 days, and at 90 days. Results: In-hospital mortality was found to be 71.4%, with cumulative mortality of 20.0% at 30 days and 31.2% at 90 days among patients discharged from the hospital. NLR and NLA demonstrated high predictive performance at all time. At admission, NLR ≥8.6 (AUC 0.92) and NLA ≥32.5 (AUC 0.89) were found to be significantly associated with mortality (p≤0.001). Both markers maintained high sensitivity and specificity at 30 and 90 days.Conclusion: NLR and NLA are simple, cost-effective prognostic markers that can reliably predict short-term mortality in alcohol-related liver disease. Their integration into routine clinical assessment will enhance early risk stratification and guide timely management decisions in cases of alcoholic liver disease.
Background: Abnormal uterine bleeding (AUB) is one of the most common gynecological complaints among reproductive-age women, often resulting from hormonal imbalances. Thyroid hormones play a crucial role in maintaining menstrual regularity and endometrial stability. This study aimed to assess the correlation between thyroid dysfunction and AUB patterns in women of reproductive age. Methods: A hospital-based cross-sectional study was conducted on 150 women aged 15-45 years presenting with AUB at a tertiary care center. Detailed clinical history, menstrual pattern, physical examination, and ultrasonographic findings were recorded. Serum T3, T4, and TSH levels were estimated using enzyme-linked immunosorbent assay (ELISA). Patients were categorized as euthyroid or having thyroid dysfunction (subclinical hypothyroidism, overt hypothyroidism, or hyperthyroidism). Data were analyzed using SPSS v25 with appropriate statistical tests, and p<0.05 was considered significant. Results: The overall prevalence of thyroid dysfunction among women with AUB was 36.0% (95% CI: 28.8-43.9%). Subclinical hypothyroidism (18.7%) was the most common abnormality, followed by overt hypothyroidism (12.0%) and hyperthyroidism (5.3%). Women with thyroid dysfunction had significantly higher BMI (27.2 ± 3.9 vs. 24.9 ± 3.6 kg/m²; p<0.001), lower hemoglobin (11.1 ± 1.6 vs. 11.9 ± 1.4 g/dL; p=0.002), and higher PBAC scores (198 ± 74 vs. 142 ± 58; p<0.001) compared to euthyroid women. Oligomenorrhea was significantly associated with hypothyroidism (30.4% vs. 14.6%; p=0.026). TSH showed a positive correlation with menstrual blood loss (r=+0.41; p<0.001) and cycle-length variability (r=+0.35; p<0.001). Conclusion: Thyroid dysfunction, particularly subclinical hypothyroidism, is prevalent among women with AUB and contributes significantly to menstrual irregularities and heavy bleeding. Routine thyroid function testing should be incorporated into the diagnostic evaluation of AUB to ensure early detection, cost-effective management, and prevention of long-term complications. Key words: Thyroid dysfunction, Abnormal uterine bleeding, Subclinical hypothyroidism.
Objectives: Postpartum family planning is a cornerstone of maternal health, but the adoption of reversible contraceptive methods remains low in India. This study evaluates the distribution and predictors of postpartum contraceptive utilization among women at an Urban Health Training Center (UHTC), Bidar, Karnataka, India, with the objectives to determine the distribution and frequency of postpartum contraceptive methods among women delivering at UHTC, Bidar, and to analyze the association between delivery mode and contraceptive choice. Materials and Methods: A prospective cross-sectional study enrolled 159 postpartum women from June to September, 2025. Data were collected on demographics, delivery details, and contraceptive choices within 6 weeks post-delivery. Analyses included descriptive statistics, contingency tables, and Chi-square test to check association using Jamovi 2.6.44 software. Results: Most women (79.2%) opted for implants; 18.9% underwent tubectomy. Very few chose intrauterine devices or oral pills (0.6% each), with only one participant opting for no method. Cesarean delivery predominated (93.7%) and showed a significantly drastic ( P < 0.001) association with implant and tubectomy. Other demographic factors were not significant predictors of contraceptive use. Conclusion: Mode of delivery, particularly cesarean section, and immediate counselling decisively influence postpartum contraceptive choices, while individual sociodemographic factors have limited impact. More focus is required on enhanced counselling to improve the adoption of reversible methods.
