Mahatma Gandhi Chitrakoot Gramodaya Vishwavidyalaya (MGCGV), formerly Chitrakoot Gramodaya Vishwavidhayalay and Mahatma Gandhi Gramodaya Vishwavidyalaya, is a first rural state university located at Chitrakoot, Madhya Pradesh, India. It was established in 1991.
In this paper, proposed an algorithm with the name LLCPT, that will trace out the offender/offenders related to a crime. The idea used in this algorithm takes into consideration that, almost everybody uses mobile phones now a days be it basic phone or smart phone. This leads us to notice that, offender/s too may use or carry a mobile phone at or near the site of crime. The LLCPT algorithm works on the principle of earth position and calculate path of mobile.
A field trial was conducted during rainy, winter and late winter seasons of 2015-16 and 2016-17 at the research farm of Krishi Vigyan Kendra, Dhar, Madhya Pradesh to study the influence of soybean [Glycine max (L.) Merrill] based cropping systems on nutrient uptake and soil fertility balance in Vertisols of Central India. In this study, 16 cropping sequences was sequenced with soybean and feasible winter viz. wheat (Triticum aestivum and Triticum durum L.), chickpea (Cicer arietinum L.), garlic (Allium sativum L.), onion (Allium cepa L.), potato (Solanum tuberosum L.), and garden pea (Pisum sativum L.) with inclusion of garlic (Allium sativum L.), onion (Allium cepa L.) in late winter and tested in randomized block design with four replications. Soybean yield equivalent (SEY) of cropping system as a whole were recorded significantly maximum in T-15-soybean (JS 93-05)-potato (Kufri jyoti)-onion (AFLR) cropping sequence (17.7 t/ha) and nitrogen use efficiency (126) as compared to existing cropping sequences (soybean-wheat and soybean-chick pea). The minimum productivity of the cropping sequence based on SEYs was registered in soybean (JS 95-60)-chickpea (JG-130) desi i.e. 4.28 t/ha however, nitrogen use efficiency (35.0) was recorded minimum in T-1-soybean (JS 95-60)-wheat (HI-1544) aestivum. The uptake of nitrogen (457 kg/ha) was observed higher under T-16-soybean (JS 93-05)-garden pea (Arkel)-garlic (G-282) while highest phosphorus (65.8 kg/ha) and potassium (562 kg/ha) uptake was recorded in T-15-soybean (JS 93-05)-potato (Kufri jyoti)-onion (AFLR) system.
The existent investigation deals with synthesis, characterization, computational analysis, and biological activities of some hydroxytriazene derivatives containing sulphonamide moiety. The compounds were screened for antidiabetic, antioxidant, and anti-inflammatory activities. The antidiabetic activity was assessed using α-glucosidase and α-amylase inhibition assays with IC50 values ranging from 32.0 to 759.13 μg/mL and 157.77 to 340.47 μg/mL while standard drug acarbose showed IC50 values 12.21 and 69.74 μg/mL, respectively. The antioxidant activity was evaluated using DPPH and ABTS radical scavenging assays with IC50 value ranging from 54.01 to 912.66 μg/mL and 33.22 to 128.11 μg/mL, and standard drug ascorbic acid showed IC50 values 29.12 μg/mL and 69.13 μg/mL, respectively. Anti-inflammatory activity was investigated using the carrageenan-induced paw edema method, where percentage inhibition was up to 93.0 and 98.57 for 2 h and 4 h, respectively, and all the compounds were found to exhibit excellent anti-inflammatory activity. Moreover, prediction of activity spectra for substance and molecular docking were also performed. The PASS prediction hypothesized the potential of the compounds for anti-inflammatory activity, and docking results suggested the best binding pose for compounds 1b and 2b with the least energy value from which compounds can be considered as potent COX-2 inhibitors. Furthermore, possible interactions between hydroxytriazene analogues and the targets of antioxidant NADPH oxidase and antidiabetic human maltase-glucoamylase enzyme have been identified. The HOMO and LUMO analysis revealed charge transfer within the compounds. These findings suggested that the synthesized compounds can be potential agents for the treatment of diabetes and inflammation.
The use of teleconsultation / telemedicine has recently undergone rapid growth and proliferation. Although the feasibility of many applications has been tested for nearly 30 years, data concerning the costs, effects, and effectiveness of telemedicine are limited. Teleconsultation / Telemedicine is a convenient tool for providing medical care remotely. It is routinely offered as an alternative to face-to-face consultations in healthcare settings all over the world. Due to the COVID-19 pandemic and increased use of telemedicine in everyday clinical practice, the effectiveness of this modality and patient satisfaction with telemedicine is a subject of growing concern. Researchgate, PubMed and Google Scholar databases were searched. Papers published between January 2020 and April 2022 which met inclusion and exclusion criteria were analyzed. During the COVID-19 pandemic patients have found telemedicine a beneficial tool for consulting healthcare providers. A high level of satisfaction with telehealth was observed in each study across every medical specialty. Telemedicine is undoubtedly a convenient tool that has helped ensure continuity of medical care during the COVID-19 pandemic thanks to its considerable potential. In particular situations, telehealth may adequately replace face-to-face consultation. Regular patients’ feedback is necessary to improve the use of telemedicine in the future.
The hydrazone Schiff base ligand isonicotinic acid (2-hydroxy-3-methoxy-benzylidene)-hydrazide ligand (H2L) has been synthesized. This ligand has been used to synthesized the six dioxidovandium(V) complexes [V(O)(2)(L)]ImH (1), [V(O)(2)(L)]2-MeImH (2), [V(O)(2)(L)]2-EthImH (3), [V(O)(2)(L)]1-MeImH (4), [V(O)(2)(L)]BezImH (5) and [V(O)(2)(L)]2-MeBenzImH (6). The ligand and complexes were characterized by FTIR, UV-Vis and other spectroscopic techniques. The used hydrazone Schiff base was also characterized by H-1 NMR, C-13 NMR and single-crystal X-ray analysis. The Hirshfeld analysis of ligand gives the most important interactions in the ligand is the O center dot center dot center dot H/H center dot center dot center dot O interactions and N center dot center dot center dot H/H center dot center dot center dot N interactions. The contribution of these interactions to the total Hirshfeld surface area is 18.7 and 8.1% respectively. The stability of vanadium was studied using cyclic voltammetry and differential pulse voltammetry. DFT calculations were carried out to correlate the electronic structures of complexes. The geometry of the vanadium(V) centre is distorted square pyramidal and distorted trigonal pyramidal. The VO2+ entity accommodated in the ONO binding site of tridentate ligand yields [V(O-2)L](-) anion.The tau(5) = 0.759-0.770 value for 1, 2 and 3 are very close to 1 authenticating the distorted trigonal bipyramidal geometry around the V(V) centre. For complexes 4, 5 and 6 the value of tau = 0.385, 0.198 and 0.010 suggesting the distorted square pyramidal geometry of V(V) centers. Antidiabetic properties of complexes were also explored using alpha-glucosidase, beta-glucosidase and alpha-amylase inhibition methods.
