N.S.S College, Ottapalam is an institute of higher education in Ottapalam, India. The college was founded in 1961. It was funded by donations and was consecrated by Swami Vishadanandha, President of Sree Ramakrishna Ashram, Palappuram, and was formally inaugurated by Mrs. Prabhakaran Thampan on 10 July 1961. In July 1962, it was upgraded and was shifted to the present site. The premises of the College consist mostly of land donated by Smt. K.P.S. Menon and Sri. Vapala Sankaranarayana Menon. The college hosts a national seminar on economics, hosted by president-in-charge, Venkatesh Athreya. It is affiliated with the University of Calicut. The current principal is Dr. Rajesh. R. It is accredited with A Grade status by the National Assessment and Accreditation Council.
The COVID-19 outbreak has had a devastating effect on India's construction industry, causing many problems and setbacks. Examining the industry from multiple angles, including social, economic, and environmental concerns, this paper seeks to assess the post-COVID situation in India's construction industry. The study examines the immediate and future consequences of the global outbreak on India's construction industry by conducting an in-depth review of the literature. It delves into the difficulties encountered by construction companies as a result of shutdown restrictions, interruptions in the supply network, scarcity of workers, and budgetary restrictions. This research also delves into what the construction industry in India can expect from the post-COVID age in terms of developments and possibilities. Sustainable and resilient building practices are becoming more important, and this article looks at how digital technologies like Building Information Modeling (BIM) and remote collaboration tools are being used. The results of this study add to our knowledge of the situation in the construction industry of India after COVID. It helps researchers, professionals in the field, and lawmakers understand the opportunities and threats posed by the dynamic construction industry. In the wake of the COVID-19 global outbreak, India's construction industry has an opportunity to help the country achieve its sustainable development goals, create jobs, and boost the economy by adjusting to new circumstances.
The structural, vibrational, electronic, and nonlinear optical properties of 4-amino benzoic acid pyrazinoic acid were obtained using spectral methods and density functional theory calculation. The title compound was characterized by Fourier transform infrared, Fourier transform-Raman, UV-Vis spectral studies and single crystal x-ray diffraction technique. By using density functional theory (DFT) using B3LYP method with 6-31 G(d,p) basis sets. The molecular geometry and vibrational frequencies were calculated and compared with the experimental data. The intermolecular contact of title compound was studied by Hirshfeld surface analysis whereas an intra-molecular hydrogen bonding interaction was examined through reduced density gradient plot. Molecular electrostatic potential and Fukui functions were also performed. Wave functional study like electron localization functions were analyzed. Bader's theory of atoms-in-molecule conjointly with natural bond orbital have been analyzed. The natural bond orbital (NBO) analysis enabled in comprehending the stability and charge delocalization in the title molecule. The first hyperpolarizability which is an important parameter for future studies of nonlinear optics (NLO) was calculated to check the potential of the molecule to be an NLO material.
Piperazin-1-ium 4-aminobenzoate monohydrate (PPAB) single crystals were grown by slow evaporation method. The grown crystal PPAB has been characterized by single-crystal X-ray diffraction, FTIR, FT-Raman, and UV-visible analysis. The B3LYP method and 6-311G (d, p) basis set were used to optimize the structure. The title compound was investigated theoretically and experimentally by FT-IR, FT-Raman, and UV-Vis spectral analysis. The presence of various functional groups in the structure was elucidated by FTIR and FT-Raman spectral studies. The intermolecular interactions within the crystal structure were investigated using Hirshfeld surface analysis. The crystal packing diagram reveals interesting non-covalent interactions involving C–H···O, N–H···O, and N–H···N hydrogen bonds, leading to the generation of 3D supramolecular architecture. The charge transfer within the molecule was deeply analyzed by using the NBO approach. The molecular electrostatic potential (MEP) and the local reactivity descriptors, such as Fukui function (fk+, fk−) analyses were performed to determine the reactive sites within the molecule. The HOMO and LUMO analysis was used to determine the chemical reactivity and bioactivity of the molecule. Hole-electron analysis was performed to analyze the charge transfer in an excited state. Based on the hole-electron analysis, the inter-fragment charge transfer (IFCT) analysis establishes the amount of charge transfer among different fragments. Topological analyses, such as AIM, RDG, and ELF were carried out to identify the non-covalent interaction within the molecule. The molecular docking studies of the molecule are performed to investigate the binding affinity of the ligand with the protein receptor. Drug-likeness properties, such as Lipinski’s rule of five, adsorption, distribution, metabolism, excretion, and toxicity (ADMET) have been investigated by in silico web-based tools like SwissADME and ADMETlab.
The structure of sulfathiazole-4-nitrobenzoic acid (STZBA) was characterized by X-ray diffraction (XRD). The crystal was stabilized by C–H…O, N–H…O, and S–O…S intermolecular interaction along with C–H…π and π…π interactions. The experimental FT-IR, FT-Raman, and UV-Vis spectra of STZBA were recorded and the results were compared with quantum chemical computation using the DFT method. Molecular electron density, topology, and natural bond orbital (NBO) analysis were used to explain the strength of the interaction. The molecular electrostatic potential and Fukui function of STZBA was determined to give a visual representation of charge distribution and provide information about the electrophilic and nucleophilic site of the molecule. Hirshfeld surface analysis was carried out to analyze the stability of the crystal structure. The antimicrobial activity of STZBA was determined against anticancer, bacterial strain E. coli and fungal stain Candida albicans and Sars-cov. Molecular docking analysis was performed with antimicrobial proteins to confirm the bioactivity of the molecule and drug likeness factors were calculated to comprehend the biological assets of STZBA. The molecular dynamic (MD) simulation result explains the protein stability, ligand properties, and protein-ligand interactions. The compounds were assessed for their structural, physic-chemical, pharmacokinetic, and toxicological properties.
Geographical indications refer to a collective Intellectual property right conferred upon products that draw unique quality on account of the environmental or human skills unique to that place. In Kerala, there are 38 registered Geographical indications. Geographical indications are often viewed as a marketing tool that supports producers and consumers. The producers can use GIs as a product differentiation tool that helps them gain a competitive advantage. Whereas for consumers GIs act as a tool that helps them overcome information asymmetry and therefore choose genuine products. The present study is done to identify the factors determining the purchase intention of customers towards handloom textiles having geographical indications. The sample for the present study is drawn from the customers of Kuthampully Textiles, a geographical indication registered in Kerala. The data collected were analyzed using factor analysis and logistic regression. The factor analysis was done to identify the main factors affecting the purchase intention of GI-tagged textiles and the logistic regression was applied to determine factor interactions.
