The construction sector in South America is a driver of economic growth, but faces increasing pressure to address resource scarcity and environmental challenges. In response, the circular economy (CE) concept has gained traction as a framework for sustainable transformation. This study investigates the adoption of the CE model among major construction companies operating in South America. A total of 65 sustainability reports from 13 companies were analyzed to identify CE practices and indicators implemented across the building life cycle stages: pre-design and design, manufacturing, construction, operation and use, and end of life. The analysis also tracks impacts over time. Results reveal that companies prioritize the end-of-life stage, followed by pre-design and design, operation and use, and construction; manufacturing is the least addressed stage. Practices include improving the quality of recovered materials, reusing in-situ concrete, advancing circular supply chains, and applying both building information modeling and pre-assembly, prefabrication, and modularization methodologies. Measurement, however, remains a key challenge. Circularity indicators are primarily reported during the pre-design and design, construction, and end-of-life stages. While impacts vary across companies, some reports demonstrate improvements in water efficiency, recycling rates, and waste reuse. Overall, findings suggest a growing adoption of circular practices; nonetheless, the integration of circularity indicators remains incipient and highly heterogeneous across companies. This research contributes to the understanding of circularity in South American construction and provides insights to advance practice.
BACKGROUND:There is limited evidence regarding the safety and efficacy of advanced hybrid closed-loop (AHCL) systems during the perioperative period. Specific management guidelines for these systems are lacking. OBJECTIVE:To describe glycemic control metrics in patients with AHCL system during the intraoperative and postoperative periods. METHODS:Analytical study based on a prospective cohort of adults with type 1 diabetes (T1D) or type 2 diabetes who are treated with AHCL system (MiniMed™780G, Medtronic, USA) and are undergoing surgical procedures. The study compared time in range (%TIR) between 70 and 180 mg/dL, time below range (%TBR) <70 and <54 mg/dL, time above range (%TAR) >180 and >250 mg/dL, and time in normoglycemia range (%TINR) between 70 and 140 mg/dL during the intraoperative, immediate postoperative, and late postoperative periods, with baseline measurements. RESULTS:The analysis included 15 patients (86% T1D; 55.4 ± 16.3 years) and 17 surgical procedures (70% elective; mean duration 65.3 ± 36.3 min). Baseline data obtained 24 h prior to the admission: %TIR 78.4 ± 17.5%, %TINR 58.6 ± 22.9%, and %TBR <70 mg/dL 3.7 ± 4.2%. During the intraoperative period, %TIR increased to 99.6 ± 1.5% (P < 0.001), and %TBR <70 mg/dL decreased to 0 (P < 0.001). %TAR >180 mg/dL decreased from 17.8 ± 16.8% to 0.1 ± 1.5% (P < 0.001). No hypoglycemic events <70 mg/dL or <54 mg/dL were documented in the intraoperative and immediate postoperative periods. No severe adverse events related to device use were recorded. CONCLUSIONS:During the perioperative period, continuing insulin infusion using AHCL system is feasible, maintaining high levels of %TIR and %TINR, without hypoglycemia or serious adverse events. Randomized clinical trials are needed to compare the use of this technology with usual care.
Preclinical evaluations of glycaemic control algorithms often rely on simulators that underestimate real-world metabolic variability, leading to overly optimistic performance assessments. A novel type 1 diabetes (T1D) simulation framework, DT1-UAN v2, was developed to generate physiologically realistic and adaptive scenarios for an improved assessment of insulin therapies. DT1-UAN v2 integrates two disturbances of intrapatient variability: eight stochastically parameterised insulin sensitivity (SI) patterns and sixty data-driven profiles for the rate of blood glucose appearance (Ra). Incorporating these features exposed vulnerabilities in insulin therapies that previously relied on static physiological parameters. In silico trials on virtual T1D subjects, under both openand closed-loop therapies, revealed contrasts between outcomes obtained with DT1-UAN v2 and the earlier DT1UAN v1. One particular test showed that a well-known closed-loop control therapy produced inferior performances (-17.57% in TIR or + 121.78% in TAR) under a set of realistic and altered conditions defined in v2 compared to v1. Control strategies that appeared effective in non-realistic scenarios often produced different results in the enhanced framework, uncovering underestimated risks of post-prandial hypoglycaemia or sustained hyperglycaemia. These findings demonstrate that incorporating realistic SI and Ra variability is essential for rigorous preclinical testing, as simplified models can conceal clinically relevant risks. The proposed framework provides a valuable tool for identifying hidden design flaws and enabling the development of more adaptive, and safer control strategies for people with T1D. This enhanced realism provides a critical foundation for testing and optimising personalised insulin treatments.
En el siglo XXI, la vanguardia tecnológica ha configurado los ecosistemas en los que habitan las sociedades contemporáneas; a partir de ello, surge una pregunta central: ¿cómo la hipermediación tecnológica impacta el desarrollo sostenible? En ese sentido, este análisis documental mixto y no experimental tiene como objetivo analizar el impacto de la inmersión tecnológica en Singapur, a través de los Objetivos de Desarrollo Sostenible (ODS), los conceptos utópicos y distópicos formulados por Orwell y Jameson y documentación oficial de la iniciativa Smart Nation y la Organización de las Naciones Unidas (ONU) con el fin de comprender si la hipermediación tecnológica es positiva o negativa para el desarrollo de las ciudades. Los hallazgos muestran que las redes IoT y los sistemas automatizados de transporte contribuyen a la eficiencia energética y la inclusión social, aunque persisten desafíos normativos. A modo de conclusión, la ciudad se perfila como un epicentro del progreso, sin
Este estudio analiza la relación dinámica entre precios de vivienda y empleo formal registrado ante el IMSS en México, con énfasis en precedencia temporal y heterogeneidad territorial. Se emplean datos trimestrales de las 32 entidades federativas para 2006T1–2025T4, combinando el Índice SHF de Precios de la Vivienda con registros administrativos del IMSS sobre puestos de trabajo asociados a salario y remuneraciones promedio. Las variables se expresan como tasas de variación anual respecto del mismo trimestre del año previo. La estrategia empírica estima VAR bivariados por entidad y aplica pruebas de causalidad en el sentido de Granger, previa verificación de estacionariedad y selección de rezagos. Los resultados muestran patrones heterogéneos: en algunas entidades, empleo o salarios anteceden cambios en precios de vivienda; en otras, los precios anticipan la evolución del empleo formal. El estudio aporta evidencia estatal comparable sobre la interacción temporal entre los mercados laboral formal e inmobiliario y documenta diferencias territoriales relevantes para su interpretación económica.
