Volgograd State Medical University is located in Volgograd which is situated in the southern part of Russia on the west bank of the Volga River. It started as Stalingrad Medical Institute founded in 1935. In 1993 it received the status of the Academy, and in 2003 it was granted the status of the University. It is currently headed by the prominent Russian scientist, Academician of the Russian Academy for Medical Sciences, Professor Vladimir I. Petrov.The University is accredited by the Russian Ministry for Education for the teaching of both Russian and overseas students. Since 2000 the Volgograd State Medical University has got an opportunity to teach foreign students in the English language.
This paper presents an annotated checklist of myxomycetes recorded from Kazakhstan, comprising 193 species accepted according to the current taxonomy. The checklist synthesizes data from a comprehensive evaluation of 26 relevant publications; species mentioned in these sources were treated as records unless explicitly referencing primary data of another study. Among the major vegetation zones, mountain coniferous forests where most diverse (115 taxa recorded), followed by forest steppe (87), semidesert (71), extra zonal forests in steppe (69), steppe (49), desert (48), and open mountain (25) biomes. Decaying wood was the most frequently reported substrate (157 records), closely followed by plant litter (155). Bark of living trees and shrubs (99) was also important, while living mosses (24) and dung (28) supported fewer, yet often highly specialized, species. Field surveys yielded 109 species, but an additional 48 species were detected via the moist chamber culture technique. Only 36 species were recovered at least once by both methods. These findings demonstrate that field surveys and moist chamber cultures complement each other, recovering distinct species assemblages. The latter method proved to be essential for detecting minute species, particularly those inhabiting desert environments.
Background. Lean principles are currently driving the development of primary healthcare, allowing organizations to reduce waste and address operational issues, as well as decrease the risk of burnout in healthcare workers. Professional burnout is a widely recognized workplace problem in both rich and poor countries, posing a serious threat not only to the social and professional lives of physicians but also to the health of their patients. Lean principles aim to improve the operational efficiency of healthcare organizations. Workforce optimization allows healthcare workers to better perform their duties, preventing (or mitigating) factors that contribute to professional burnout, and helps ensure the required accessibility and quality of healthcare.Objective. To analyze the relationship between the experience of healthcare workers in lean principles and the level of professional burnout among employees of healthcare organizations under modern conditions.Methods. A single-center prospective survey study was conducted based on a questionnaire survey completed by 201 healthcare workers from organizations providing primary care. In the study, the authors used an original questionnaire entitled “Lean Competencies of Healthcare Professionals,” as well as the burnout assessment tool developed by Christina Maslach and Susan Jackson and adapted for physicians by Natalia Vodopyanova (Attitude to Work and Professional Burnout). The survey was carried out using Online Test Pad, a multifunctional online service for conducting tests and training. The main focus of the study was to assess statistically significant correlations between the level of professional burnout in healthcare workers and their experience in lean principles. In order to assess the level of burnout among healthcare workers, the authors used a validated procedure developed by Natalia Vodopyanova, which is based on Maslach and Jackson’s three-dimensional model of burnout, comparing the results with those of a survey aimed at evaluating the experience in lean principles. The study results were statistically analyzed using IMB SPSS Statistics software (version 23; StatSoft, USA). The results were considered statistically significant at p < 0.05.Results. The study revealed that as healthcare workers gain experience in lean projects, they experience lower levels of professional burnout. Participation in project teams working to improve healthcare organizations was inversely correlated with emotional exhaustion, work-related stress, lack of on-the-job development, and low overall self-esteem: healthcare workers with a greater commitment to lean principles suffered less from reduced personal accomplishment, which is part of professional burnout.Conclusion. Further research into the relationship between the application of lean principles in medicine and the level of professional burnout among healthcare workers could improve the quality of healthcare and workforce productivity in this industry.
Existing incident management systems are based on the registration of all adverse events resulting from changes in operational circumstances and conditions that have caused or could potentially cause harm to patients or staff members. In higher education institutions, incidents may arise at any stage of the educational process and operational activities of the university, ranging from minor issues and technical failures to serious situations, violence, and security threats. In order to improve the efficiency of higher education institutions implementing professional medical and pharmaceutical educational programs, the Minister of Health of the Russian Federation, M.A. Murashko, instructed educational institutions to ensure the implementation of incident management systems in their operations. The authors propose an algorithm for implementing incident management in educational institutions based on the experience of Volgograd State Medical University.
The main objective in performing staged minimally invasive surgical correction of portal hypertension, as a basis for the prevention and treatment of portal bleeding, is the correct selection of initial and subsequent interventions while adhering to the concept of an individualized approach. Objective . To improve the outcomes of treatment and prevention of portal bleeding in patients with liver cirrhosis. Material and research methods . A comparative controlled study was conducted on the treatment outcomes of 295 patients with cirrhotic portal hypertension between 2006 and 2025. Group 1 ( n = 109) underwent staged combined minimally invasive surgical treatment and prevention of portal bleeding. Group 2 ( n = 84) consisted of patients who received only endoscopic methods. Group 3 ( n = 102) included patients who received only conservative therapy. Research results . The frequency of complications after endoscopic procedures didn’t depend on a history of bleeding and was the same in groups 1 and 2. The correlation between functional class and the development of complications after minimally invasive azygoportal disconnection ( n = 65) was not statistically significant ( p = 0.491). Inverse correlations were found between the initial sagittal size of the spleen and the baseline levels of thrombocytopenia and leukopenia in patients who received splenic blood flow reduction. After transjugular portosystemic shunting, regression of esophageal and gastric varices was noted in 81.58 % of cases ( p < 0.0001). The most common combination was endoscopic band ligation of esophageal varices, azygoportal disconnection surgery, and splenic blood flow reduction ( n = 21). The choice of the initial method depended on the presence or risk of bleeding. Group 3 had a much higher mortality (7 times higher) than group 2 ( p < 0.0001). In group 1, the mortality rate is 3 times lower than in group 2 ( p < 0.0001). Conclusion . The use of minimally invasive surgical correction of portal hypertension, following an individualized approach based on the predominant complication, allows for a reduction in mortality.
The antidepressant properties of DAB-21 a compound with anxiolytic activity, were studied in C57BL/6 mice after modeling chronic unpredictable mild stress. In the Porsolt swim and tail suspension tests, the effect of DAB-21 was similar to that of amitriptyline, imipramine, and fluoxetine. In the open field test, the substance did not stimulate the motor activity of animals, which excludes the pseudo-antidepressant effect. HPLC analysis of monoamines and their metabolites in the frontal cortex showed that the 5-HIAA/serotonin ratio in animals treated with DAB-21 was 0.1, which is closest to that in the fluoxetine group. These findings suggest that the anxiolytic and antidepressant effects of DAB-21 are mediated via the serotonergic pathway.
