
Chronic graft-versus-host disease (cGVHD) affects up to 54% of allogeneic hematopoietic cell transplantation recipients and is the leading cause of late non-relapse morbidity and mortality. Despite the availability of National Institutes of Health consensus criteria, Foundation for the Accreditation of Cellular Therapy accreditation standards, and CIBMTR reporting requirements, standardized screening practices remain inconsistent. The Engraft Learning Health Network (LHN) conducted a multicenter assessment to characterize cGVHD screening practices across participating transplant centers. To characterize current cGVHD screening practices across participating transplant centers within the Engraft LHN, identify areas of practice variation, and inform development of a standardized screening approach. This multicenter qualitative study included 10 transplant centers (8 pediatric and 2 adult) within the Engraft LHN. Thirty-three structured interviews were conducted with clinician representatives using a standardized guide addressing eight screening domains: assessment schedules, documentation practices, and organnary, and musculoskeletal systems. Interview summaries were validated by participants and analyzed to quantify screening practices across centers using descriptive statistics