在中医学理论体系中,痹、痿两种疾病在病因病机、辨证论治方面均不相同,但痹病可以导致痿病的发生.类风湿关节炎主要影响肢体关节,亦可影响筋脉肌肉,从而形成痹痿并存的症状."脾虚"在痹与痿的发病、发展以及演变中具有重要作用.脾虚为本,营卫失和,外湿引动内湿,湿邪困脾,加重脾虚,影响五脏,故外及肢体,内及脏腑.病情进一步发展,脾虚失养,或脾虚湿阻,因痹致痿,故出现肉痿筋弛,肺痿咳喘.据此提出:健脾化湿,以调营卫、滋气血、利关节、濡肌肉、强筋骨,同时兼顾补脾养五脏,通五脏痹,养五脏痿.故从脾论治类风湿关节炎,可以涵盖类风湿关节炎各个病理阶段,实现痹与痿同治.
Double heart disease is a general term for a group of cardiovascular diseases combined with psychosomatic problems,which is a common disease in cardiology,but there are no effective cures"and"methods at present.In view of double heart disease,combining with the physiological function of"heart governs blood and heart governs Shen"in traditional Chinese medicine and the living characteristics of modern people,Professor Liu Hongxu believes that the pathological characteristics of double heart disease are liver excess and spleen deficiency,Yang excess and Yin deficiency,and the imbalance of the liver and the spleen is the important mechanism of the disease,so the general principle is to adjust the liver and the spleen together.Symptoms manifestation focuses on the emotional disturbances,poor appetite and fatigue,red tongue and stringy pulse,the treatment adopts the method which relieves the depression and clears away the heat,strengthens the spleen and nourishes the heart,the dispatch prescription uses the medicine to Danzhi Xiaoyao powder to add the subtraction,with the symptom to be tailored.This paper summarizes Professor Liu Hongxu based on the liver and spleen same adjustment theory of treatment of double heart disease ideas and experience with medicine,and attached to a medical case,to support the description.
Peroxisome proliferator-activated receptor(PPAR)is a kind of transcription factor that is involved in sugar and lipid metabolism,inflammatory response and cell proliferation,differentiation,and apoptosis.In recent years,an increasing number of studies have been conducted on the related pathways of the three subtypes of PPAR,and it has been found that PPAR played an important role in the transformation process of non-alcoholic fatty liver disease.From monomer and compound Chinese medicine to patent Chinese medicine and external treatment of traditional Chinese medicine(TCM),all of which showed that TCM intervention had a good clinical effect on the treatment of non-alcoholic fatty liver disease(NAFLD).The number of fundamental experiment studies to elucidate the mechanism of TCM in the prevention and treatment of NAFLD based on PPAR pathways is increasing.This article will review the experimental studies on the mechanism of TCM prevention and treatment of NAFLD in recent years from the perspective of PPAR pathways.
腹型过敏性紫癜是以腹部疼痛为主要表现的免疫紊乱性小血管炎性疾病,甚者可并发急腹症,严重危害患儿身心健康,目前认为其发病机制与"肠道微生态-免疫炎症"失调有关.糖皮质激素是西医推荐的首选用药.近年来中医药治疗本病疗效日渐显著,但具体机制不明.故本文从中医"阳明"为切入点,阐释肠道"微生态-免疫炎症"失衡与"阳明有余"二者之间的联系与内涵,为中医药靶向"微生态-免疫炎症"治疗和预防腹型过敏性紫癜提供新的研究思路.
Objective This study aims to examine the utilization of Elemene Emulsion Injection in combination with other drugs for the treatment of esophageal cancer.Method From 21 tertiary hospitals across the country,clinical records of 310 patients,who received Elemene Emulsion Injection for esophageal cancer,were retrieved from the Hospital Information System(HIS).These patient data were subjected to descriptive analysis focusing on their diagnostic and medication details.Applying the modularity optimization feature of the Louvain algorithm for multi-level networks,an exploration into the key medication regimens for the most effectively treated patient group was conducted.Results Among esophageal cancer patients treated with Elemene Emulsion Injection,hypertension,diabetes,coronary heart disease,and lung infection frequently co-occur.The predominant mode of administration is via intravenous drip.The range of dosage per administration is between 20 mL and 200 mL;most patients are treated with a course lasting no more than three days.Concomitant Western medicines primarily encompass nutritional supplements,vitamins,insulin injections,and their respective analogs.Additionally,co-administered Chinese Patent Medicine often include Xiaoaiping Injection,Yadanzi Oil Emulsion Injection,and Compound Bitter Sophora Injection.Moreover,Elemene Emulsion Injection is regularly paired with potassium chloride,heparins,thymopeptide,dexamethasone,vitamins,and furosemide.Conclusion The integration of Elemene Emulsion Injection in the clinical management of esophageal cancer adheres to pertinent clinical guidelines.The collaborative application of Chinese Patent Medicine and modern Western Medicine primarily addresses the nutritional status of patients,adverse reactions following surgery or radiation and chemotherapy,overlapping conditions,complications,and supportive treatment for symptoms.This offers a valuable reference point for esophageal cancer treatment strategies.
